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Peters A, Rospleszcz S, Greiser KH, Dallavalle M, Berger K; Complete list of authors available under: Collaborators. The impact of the COVID-19 pandemic on self-reported health. Dtsch Arztebl Int 117(50): 861-867, 2020. doi: 10.3238/arztebl.2020.0861
Brinkmann V, Schiavi A, Shaik A, Puchta DR, Ventura N: Dietary and environmental factors have opposite AhR-dependent effects on C. elegans healthspan. Aging (Albany NY) 13(1): 104-133, 2020. doi: 10.18632/aging.202316
Vargas-Toscano A, Nickel A-C, Li G, Kamp MA, Muhammad S, Leprivier G, Fritsche E, Barker RA, Sabel M, Steiger HJ, Zhang W, Hänggi D, Kahlert UD: Rapalink-1 targets glioblastoma stem cells and acts synergistically with tumor treating fields to reduce resistance against temozolomide. Cancers 12(12): 3859, 2020. doi: 10.3390/cancers12123859
Fischer I, Nickel A-C, Qin N, Taban K, Pauck D, Steiger H-J, Kamp M, Muhammad S, Hänggi D, Fritsche E, Remke M, Kahlert UD: Different calculation strategies are congruent in determining chemotherapy resistance of brain tumors in vitro. Cells 9(12): 2689, 2020. doi: 10.3390/cells9122689
Nothdurft S, Thumser-Henner C, Breitenbücher F, Okimoto RA, Dorsch M, Opitz CA, Sadik A, Esser C, Hölzel M, Asthana S, Forster J, Beisser D, Kalmbach S, Grüner BM, Bivona TG, Schramm A, Schuler M: Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis. Oncogenesis 9(11): 102, 2020. doi: 10.1038/s41389-020-00286-8
Dahlem C, Kado SY, He F, Bein K, Wu D, Haarmann-Stemmann T, Kado NY, Vogel CF: AHR signaling interacting with nutritional factors regulating the expression of markers in vascular inflammation and atherogenesis. Int J Mol Sci 21(21): 8287, 2020. doi: 10.3390/ijms21218287
Tsiampali J, Neumann S, Giesen B, Koch K, Maciaczyk D, Janiak C, Hänggi D, Maciaczyk J: Enzymatic activity of CD73 modulates invasion of gliomas via epithelial-mesenchymal transition-like reprogramming. Pharmaceuticals 13(11): 378, 2020. doi: 10.3390/ph13110378
Kolling J, Tigges J, Hellack B, Albrecht C, Schins RP: Evaluation of the NLRP3 inflammasome activating effects of a large panel of TiO2 nanomaterials in macrophages. Nanomaterials 10(9): 1876, 2020. doi: 10.3390/nano10091876
Pavez-Lorie E, Stricker N, Plitta-Michalak B, Peng-Chen I, Volkmer B, Greinert R, Jauch A, Boukamp P, Rapp, A: Characterisation of the novel spontaneously immortalized and invasively growing human skin keratinocyte line HaSKpw. Sci Rep 10: 15196, 2020. doi: 10.1038/s41598-020-71315-0
Pemp D, Geppert LN, Wigmann C, Kleider C, Hauptstein R, Schmalbach K, Ickstadt K, Esch HL, Lehmann L: Influence of breast cancer risk factors and intramammary biotransformation on estrogen homeostasis in the human breast. Arch Toxicol 94(9): 3013-3025, 2020. doi: 10.1007/s00204-020-02807-1
Feng X, Flexeder C, Markevych I, Standl M, Heinrich J, Schikowski T, Koletzko S, Herberth G, Bauer CP, von Berg A, Berdel D, Astell-Burt T: Impact of residential green space on sleep quality and sufficiency in children and adolescents residing in Australia and Germany. Int J Environ Res Public Health 17(13): 4894, 2020. doi: 10.3390/ijerph17134894
Hippe A, Braun SA, Oláh P, Gerber PA, Schorr A, Seeliger S, Hotz S, Jannasch K, Pivarci A, Buhren B, Schrumpf H, Kislat A, Bünemann E, Steinhoff M, Fischer J, Lira SA, Boukamp P, Hevezi P, Stoecklein NH, Hoffmann T, Alves F, Sleeman J, Bauer T, Klufa J, Amberg N, Sibilia M, Zlotnik A, Müller-Homey A, Homey B: EGFR/Ras-induced CCL20 production modulates the tumour microenvironment. Br J Cancer 123: 942-954, 2020. doi: 10.1038/s41416-020-0943-2
Negele L, Flexeder C, Koletzko S, Bauer CP, von Berg A, Berdel D, Schikowski T, Standl M, Peters A, Schulz H: Association between objectively assessed physical activity and sleep quality in adolescence. Results from the GINIplus and LISA studies. Sleep Med 72: 65-74, 2020. doi: 10.1016/j.sleep.2020.03.007
Wahle T, Sofranko A, Dekkers S, Miller MR; Heusinkveld HJ, Albrecht C, Cassee FR, Schins RPF: Evaluation of neurological effects of cerium dioxide nanoparticles doped with different amounts of zirconium following inhalation exposure in mouse models of Alzheimer’s and vascular disease. Neurochem Int 138: 104755, 2020. doi: 10.1016/j.neuint.2020.104755
Kämpfer AAM, Busch M, Schins RPF: Advanced in vitro testing strategies and models of the intestine for nanosafety research. Chem Res Toxicol 33(5): 1163-1178, 2020. doi: 10.1021/acs.chemrestox.0c00079
Abramson MJ, Wigmann C, Altug H, Schikowski T: Ambient air pollution is associated with airway inflammation in older women: a nested cross-sectional analysis. BMJ Open Respir Res 7: e000549, 2020. doi: 10.1136/bmjresp-2019-000549
Baswan SM, Marini A, Klosner AE, Jaenicke T, Leverett J, Murray M, Gellenbeck KW, Krutmann J: Orally administered mixed carotenoids protect human skin against ultraviolet A-induced skin pigmentation: A double-blind, placebo-controlled, randomized clinical trial. Photodermatol Photoimmunol Photomed 36(3): 219-225, 2020. doi: 10.1111/phpp.12541
Häselbarth L, Ouwens DM, Teichweyde N, Hochrath K, Merches K, Esser C: The small chain fatty acid butyrate antagonizes the TCR-stimulation-induced metabolic shift in murine epidermal gamma delta T cells. EXCLI J 19: 334-350, 2020. doi: 10.17179/excli2020-1123
Madhusudhan N, Pausan MR, Halwachs B, Durdević M, Windisch M, Kehrmann J, Patra V, Wolf P, Boukamp P, Moissl-Eichinger C, Cerroni L, Becker JC, Gorkiewicz G: Molecular profiling of keratinocyte skin tumors links Staphylococcus aureus overabundance and increased human β-Defensin-2 expression to growth promotion of squamous cell carcinoma. Cancers (Basel) 12(3): 541, 2020. doi: 10.3390/cancers12030541
Boots AW, Veith C, Albrecht C, Bartholome R, Drittij MJ, Claessen SMH, Bast A, Rosenbruch M, Jonkers L, van Schooten FJ, Schins RPF: The dietary antioxidant quercetin reduces hallmarks of bleomycin-induced lung fibrogenesis in mice. BMC Pulm Med 20: 112, 2020. doi: 10.1186/s12890-020-1142-x
Nimtz L, Hartmann J, Tigges J, Masjosthusmann S, Schmuck M, Keßel E, Theiss S, Köhrer K, Petzsch P, Adjaye J, Wigmann C, Wieczorek D, Hildebrandt B, Bendt F, Hübenthal U, Brockerhoff G, Fritsche E: Characterization and application of electrically active neuronal networks established from human induced pluripotent stem cell-derived neural progenitor cells for neurotoxicity evaluation. Stem Cell Res 45: 101761, 2020. doi: 10.1016/j.scr.2020.101761
Pavez Loriè E, Boukamp P: Methods in cell biology: Cell-derived matrices. Methods Cell Biol 156: 309-332, 2020. doi: 10.1016/bs.mcb.2019.11.012
Merches K, Schiavi A, Weighardt H, Steinwachs S, Teichweyde N, Förster I, Hochrath K, Schumak B, Ventura N, Petzsch P, Köhrer K, Esser C: AHR signaling dampens inflammatory signature in neonatal skin γδ T cells. Int J Mol Sci 21(6): 2249, 2020. doi: 10.3390/ijms21062249
Wang Q, Zhao Q, Wang G, Wang B, Zhang Y, Zhang J, Li N, Zhao Y, Qiao H, Li W, Liu X, Liu L, Wang F, Zhang Y, Guo Y: The association between ambient temperature and clinical visits for inflammation-related diseases in rural areas in China. Environ Pollut 261: 114128, 2020. doi: 10.1016/j.envpol.2020.114128
Schikowski T*, Wigmann C*, Fuks KB*, et al.: Blutdruckmessung in der NAKO – methodische Unterschiede, Blutdruckverteilung und Bekanntheit der Hypertonie im Vergleich zu anderen bevölkerungsbezogenen Studien in Deutschland. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63(4): 452-464, 2020. doi: 10.1007/s00103-020-03109-8 (* equal contribution)
weitere Beiträge zur NAKO im Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz:
March 2020, issue 3: Die Basiserhebung der NAKO Gesundheitsstudie – Teil I: Erste Ergebnisse zu sozialen und medizinischen Faktoren
April 2020, issue 4: Die Basiserhebung der NAKO Gesundheitsstudie – Teil II: Erste Ergebnisse zu häufigen Volkskrankheiten
Altuğ H, Fuks KB, Hüls A, Mayer AK, Tham R, Krutmann J, Schikowski T: Air pollution is associated with depressive symptoms in elderly women with cognitive impairment. Environ Int 136: 105448, 2020. doi: 10.1016/j.envint.2019.105448
Tan Y, Wang F, Fan G, Yan Z, Li B, Li N, Liu Y, Wang X, Liu W, Krutmann J, Zou Y, Wang S: Identification of factors associated with minimal erythema dose variations in a large-scale population study of 22 146 subjects. J Eur Acad Dermatol Venereol 34(7): 1595-1600, 2020. doi: 10.1111/jdv.16206
Lademann J, Richter H, Patzelt A, Meinke MC, Gross I, Grether-Beck S, Krutmann J, Frazier L, Darvin ME: Laser scanning microscopy for control of skin decontamination efficacy from airborne particulates using highly absorbent textile nanofiber material in combination with PEG-12 dimethicone. Skin Res Technol 26(4): 558-563, 2020. doi: 10.1111/srt.12830
Uhlmann C, Kuhn LM, Tigges J, Fritsche E, Kahlert DU: Efficient modulation of TP53 expression in human induced pluripotent stem cells. Curr Protoc Stem Cell Biol 52(1): e102, 2020. doi: 10.1002/cpsc.102
Thyssen JP, Ahluwalia TS, Paternoster L, Ballardini N, Bergström A, Melén E, Chawes B, Stokholm J, Hourihane JO, O'Sullivan DM, Bager P, Maelbye M, Bustamante M, Torrent M, Esplugues A, Duijts L, Hu C, Elbert NJ, Pasmans SGMA, Nijsten TEC, von Berg A, Standl M, Schikowski T, Herberth G, Heinrich J, Lee YA, Marenholz I, Lau S, Curtin JA, Simpson A, Custovic A, Pennell CE, Wang CA, Holt PG, Bisgaard H, Bønnelykke K: Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis. Allergy 75(6): 1481-1485, 2020. doi: 10.1111/all.14162
Mekic S, Hamer MA, Wigmann C, Gunn DA, Kayser M, Jacobs LC, Schikowski T, Nijsten T, Pardo LM: Epidemiology and determinants of facial telangiectasia: a cross-sectional study. J Eur Acad Dermatol Venereol 34(4): 821-826, 2020. doi: 10.1111/jdv.15996
Grether-Beck S, Marini A, Jaenicke T, Goessens-Rück P, McElwee KJ, Hoffmann R, Krutmann J: Autologous cell therapy for aged human skin: a randomized, placebo-controlled, phase-I study. Skin Pharmacol Physiol 33: 9-16, 2020. doi: 10.1159/000502240
Trullàs C, Granger C, Lim HW, Krutmann J, Masson P: Linear and exponential sunscreen behaviours as an explanation for observed discrepancies in sun protection factor testing. Photodermatol Photoimmunol Photomed 36(5): 351-356, 2020. doi: 10.1111/phpp.12500
Fritsche E, Tigges J, Hartmann J, Kapr J, Serafini MM, Viviani B: Neural in vitro models for studying substances acting on the central nervous system. Handb Exp Pharmacol 2020. doi: 10.1007/164_367
White A, Kanninen K, Malm T, Schins RPF: Editorial: Air pollution and brain health. Neurochem Int 141: 104900, 2020. doi: 10.1016/j.neuint.2020.104900
Lettieri-Barbato D, Ventura N, Faraonio K, Aquilano K: Editorial: Advances in metabolic mechanisms of aging and its related diseases. Front Physiol 11: 594974, 2020. doi: 10.3389/fphys.2020.594974
Alkotob SS, Cannedy C, Harter K, Movassagh H, Paudel B, Prunicki M, Sampath V, Schikowski T, Smith E, Zhao Q, Traidl-Hoffmann C, Nadeau KC: Advances and novel developments in environmental influences on the development of atopic diseases. Allergy 75(12): 3077-3086, 2020. doi: 10.1111/all.14624
Samoli E, Rodopoulou S, Schneider A, Morawska L, Stafoggia M, Renzi M, Breitner S, Lanki T, Pickford R, Schikowski T, Okokon E, Zhang S, Zhao Q, Peters A: Meta-analysis on short-term exposure to ambient ultrafine particles and respiratory morbidity. Eur Respir Rev 29(158): 200116, 2020. doi: 10.1183/16000617.0116-2020
Masjosthusmann S, Blum J, Bartmann K, Dolde X, Holzer A-K, Stürzl L-C, Keßel EH, Förster N, Dönmez A, Klose J, Pahl M, Waldmann T, Bendt F, Kisitu J, Suciu I, Hübenthal U, Mosig A, Leist M, Fritsche E: Establishment of an priori protocol for the implementation and interpretatiom of an in-vitro testing battery for the assessment of developmental neurotoxicity. EFSA Supporting Publications 17(10): 1938E, 2020. doi: 10.2903/sp.efsa.2020.EN-1938
Sies H: Schrödingers Koffer. BIOspektrum 26: 345-346, 2020. doi: 10.1007/s12268-020-1364-8
Sies H: Oxidative stress: Concept and some practical aspects. Antioxidants 9(9): 852, 2020. doi: 10.3390/antiox9090852
Sies H: Findings in redox biology: from H2O2 to oxidative stress. J Biol Chem 295(39): 13458-13473, 2020. doi: 10.1074/jbc.X120.015651
Piechulek A, Berwanger L, Scharf A, von Mikecz A: The cell nucleus as sensor of environmental pollution: Amyloid, neurodegeneration and aging. Biopolym Cell 35: 195-196, 2019. doi: 10.7124/bc.0009CC
Fritsche E, Hogberg HT: A Brainer on Neurotoxicity. Frontiers in Toxicol 2: 3, 2020. doi: 10.3389/ftox.2020.00003
von Mikecz A, Schikowski T: Effects of airborne nanoparticles on the nervous system: amyloid protein aggregation, neurodegeneration and neurodegenerative diseases. Nanomaterials 10(7): 1349, 2020. doi: 10.3390/nano10071349
Passeron T, Krutmann J, Andersen ML, Katta R, Zouboulis CC: Clinical and biological impact of the exposome on the skin. J Eur Acad Dermatol Venereol 34 (Suppl 4): 4-25, 2020. doi: 10.1111/jdv.16614
Sies H, Parnham MJ: Potential therapeutic use of ebselen for COVID-19 and other respiratory viral infections. Free Radic Biol Med 156: 107-112, 2020. doi: 10.1016/j.freeradbiomed.2020.06.032
Esser C, Boots AM, Caignard A, Ciraci C, Grčević D, Knapp S, Montoya M, Di Rosa F, Saksida T, Stravinskiene D, Deniz G: The impact of COVID-19 lock-downs for European (female) immunologists – our views as members of the EFIS gender and diversity task force. Euro J Immunol 50(12): 1855-1862, 2020. doi: 10.1002/eji.202070125
Esser C, Hochrath K, Schikowski T, Haarmann-Stemmann T: COVID-19 research: toxicological input urgently needed! Arch Toxicol 94(7): 2547-2548, 2020. doi: 10.1007/s00204-020-02803-5
Lupu D, Andersson P, Bornehag CG, Demeneix B, Fritsche E, Gennings C, Lichtensteiger W, Leist M, Leonards PEG, Ponsonby AL, Scholze M, Testa G, Tresguerres JAF, Westerink RHS, Zalc B, Rüegg J: The ENDpoiNTs project: Novel testing strategies for endocrine disruptors linked to developmental neurotoxicity. Int J Mol Sci 21: 3978, 2020. doi: 10.3390/ijms21113978
Bernhard GH, Neale RE, Barnes PW, Neale PJ, Zepp RG, Wilson SR, Andrady AL, Bais AF, McKenzie RL, Aucamp PJ, Young PJ, Liley JB, Lucas RM, Yazar S, Rhodes LE, Byrne SN, Hollestein LM, Olsen CM, Young AR, Robson TM, Bornman JF, Jansen MAK, Robinson SA, Ballaré CL, Williamson CE, Rose KC, Banaszak AT, Häder DP, Hylander S, Wängberg SÅ, Austin AT, Hou WC, Paul ND, Madronich S, Sulzberger B, Solomon KR, Li H, Schikowski T, Longstreth J, Pandey KK, Heikkilä AM, White CC: Environmental effects of stratospheric ozone depletion, UV radiation and interactions with climate change: UNEP Environmental Effects Assessment Panel, update 2019. Photochem Photobiol Sci 19(5): 542-584, 2020. doi: 10.1039/d0pp90011g
Thurston GD, Balmes JR, Garcia E, Gilliland FD, Rice MB, Schikowski T, Van Winkle LS, Annesi-Maesano I, Burchard EG, Carlsten C, Harkema JR, Khreis H, Kleeberger SR, Kodavanti UP, London SJ, McConnell R, Peden DB, Pinkerton KE, Reibman J, White CW: Outdoor air pollution and new-onset airway disease. An official American Thoracic Society workshop report. Ann Am Thorac Soc 17(4): 387-398, 2020. doi: 10.1513/AnnalsATS.202001-046ST
Schiavi A, Strappazzon F, Ventura N: Mitophagy and iron: two actors sharing the stage in age-associated neuronal pathologies. Mech Ageing Dev 188: 111252, 2020. doi: 10.1016/j.mad.2020.111252
Vogel CFA, Van Winkle LS, Esser C, Haarmann-Stemmann T: The aryl hydrocarbon receptor as a target of environmental stressors – Implications for pollution mediated stress and inflammatory responses. Redox Biol 34: 101530, 2020. doi: 10.1016/j.redox.2020.101530
Sies H, Jones DP: Reactive oxygen species (ROS) as pleiotropic physiological signalling agents. Nat Rev Mol Cell Biol 21(7): 363-383, 2020. doi: 10.1038/s41580-020-0230-3
Schikowski T, Altug H: The role of air pollution in cognitive impairment and decline. Neurochem Int 21: 104708, 2020. doi: 10.1016/j.neuint.2020.104708
Schikowski T, Hüls A: Air pollution and skin aging. Curr Environ Health Rep 7(1): 58-64, 2020. doi: 10.1007/s40572-020-00262-9
Brinkmann V, Schiavi A, Shaik A, Puchta DR, Ventura N: Dietary and environmental factors have opposite AhR-dependent effects on C. elegans healthspan. Aging (Albany NY) 13(1): 104-133, 2020. doi: 10.18632/aging.202316
Krutmann J, Passeron T, Gilaberte Y, Granger C, Leone G, Narda M, Schalka S, Trullas C, Masson P, Lim HW: Photoprotection of the future: Challenges and opportunities. J Eur Acad Dermatol Venereol 34(3): 447-454, 2020. doi: 10.1111/jdv.16030
Barenys M, Reverte I, Masjosthusmann S, Gómez-Catalán J, Fritsche E: Developmental neurotoxicity of MDMA. A systematic literature review summarized in a putative adverse outcome pathway. Neurotoxicology 78: 209-241, 2020. doi: 10.1016/j.neuro.2019.12.007