Krutmann Archive

Brown A, Passeron T, Granger C, Gilaberte Y, Trullas C, Piquero-Casals J, Leone G, Schalka S, Lim HW, Krutmann J: Ingredients for oral photoprotection: An evidence-based classification. J Am Acad Dermatol 94(2): 699-703, 2026. doi: 10.1016/j.jaad.2025.10.062

Brown A, Passeron T, Gilaberte Y, Piquero-Casals J, Schalka S, Simonetto C, Foyaca M, Lim HW, Krutmann J: Biological Photoprotection: A Review of its Mechanisms, Evidence, and Clinical Implications. Dermatol Ther (Heidelb) 16(7): 3633-3648, 2026. doi: 10.1007/s13555-026-01805-y

Brown A, Passeron T, Gilaberte Y, Piquero-Casals J, Schalka S, Simonetto C, Foyaca M, Lim HW, Krutmann J: Biological...

Hamam-Marawi G, Papadopoulou M, Ramachandran H, Dobner J, Binder S, Hildebrandt B, Krutmann J, Rossi A: CRISPR/Cas9-mediated editing of ERCC6 in iPSCs: a disease model for Cockayne Syndrome type B. Stem Cell Res 95: 104044, 2026. doi: 10.1016/j.scr.2026.104044

Xia J, Kuzyakov Y, Krutmann J: Microbial diversity as a proxy for skin health: an ecological framework misapplied. Br J Dermatol 2026. doi: 10.1093/bjd/ljag251

Xia J, Kuzyakov Y, Krutmann J: Microbial diversity as a proxy for skin health: an ecological framework misapplied. B...

Krutmann J, Puig S, Dreno B, Ocampo Candiani J, Ly F, Schalka S, Wei L, Morita A, Goh CL, Kang HY, Demessant-Flavigny AL, Taieb C, Le Floc’h C, Kerob D, Lim HW, Alexis A, Passeron T: Prevalence and impact of solar lentigines: an international survey. J Eur Acad Dermatol Venereol 2026. doi: 10.1111/jdv.70522

Ramachandran H, Dobner J, Nguyen T, Binder S, Tolle I, Vykhlyantseva I, Krutmann J, Miccio A, Staerk C, Brusson M, Kontarakis Z, Prigione A, Rossi A: CleanFinder: a scalable framework for comprehensive genome editing analysis. Trends Biotechnol 2026. doi: 10.1016/j.tibtech.2026.04.024

Anarat A, Krutmann J, Schwender H: A nonparametric statistical method for deconvolving densities in the analysis of proteomic data. BMC Bioinformatics 27(1): 83, 2026. doi: 10.1186/s12859-026-06408-0

Dimmers F, Lück N, Wang Y, Staerk C, Zhang T, Krutmann J: Sunscreen efficacy against UVA1- and visible light-induced skin pigmentation is influenced by ancestry. Photodermatol Photoimmunol Photomed 42(3): e70094, 2026. doi: 10.1111/phpp.70094 (* equal contribution)

Lim HW, Schalka S, Trautinger F, Baptista MS, Chien AL, Cole C, Gilaberte Y, González S, Hamzavi I, Krutmann J, Kohli I, Osterwalder U, Rodrigues M, Passeron T: International modified Delphi consensus statement on visible light photoprotection: Effects, measurement, and recommendations. J Invest Dermatol 2026. doi: 10.1016/j.jid.2026.03.012

Piquero-Casals J, Bertold C, Alomar A, Morgado-Carrasco D, Gilaberte Y, López-Estebaranz JL, Massa A, de Castro CS, Leone G, Lim HW, Krutmann J, Ezzedine K, Passeron T: Exposome risk factors for vitiligo: A systematic evidence review. Am J Clin Dermatol 2026. doi: 10.1007/s40257-026-01012-7

Passeron T, Lim HW, Goh CL, Kang HY, Ly F, Morita A, Ocampo-Candiani J, Puig S, Schalka S, Wei L, Demessant AL, Taïeb C, Le Floc’h C, Kerob D, Krutmann J: Patterns of regret for inadequate sun protection: A population-based study [HELIOS]. J Eur Acad Dermatol Venereol 40(8): e706-e708, 2026. doi: 10.1111/jdv.70385

Dimmers F, Reichert D, Nguyen T, Lück N, Ramachandran H, Bremges A, Schild J, Humbek M, Grether-Beck S, Rossi A, Staerk C, Esser C, Krutmann J: Monocentric, vehicle-controlled, double-blind study to assess the short- and long-term effects of a Ceramide NP C15-containing emollient on the skin microbiome and the skin barrier function in sensitive skin. Skin Pharmacol Physiol 27: 1-18, 2026. doi: 10.1159/000551043

Singh N, Schikowski T, Krutmann J: Air pollution and skin diseases: A systematic review of epidemiological evidence. Am J Clin Dermatol 27(2): 261-276, 2026. doi: 10.1007/s40257-026-01006-5

Dimmers F, Reichert D, Wigmann C, Trullàs C, Piquero-Casals J, Brown A, Foyaca M, Esser C, Krutmann J: Effects of solar-simulated (UVB plus UVA) radiation on the skin microbiome: An exploratory study. Photochem Photobiol 2026. doi: 10.1111/php.70078

Krutmann J, Merk HF, Haarmann-Stemmann T: Umweltdermatologie. Dermatologie (Heidelb) 77(2): 71-72, 2026. doi: 10.1007/s00105-025-05629-3

Dimmers F, Wigmann C, Zhang T, Czech P, Wang S, Krutmann J, Schikowski T: The relationship between sensitive skin and skin aging in Han Chinese. Exp Dermatol 34(12): e70190, 2025. doi: 10.1111/exd.70190

Rolfes KM, Haarmann-Stemmann T, Krutmann J: Auswirkungen partikulärer Luftverschmutzung auf die menschliche Haut. Dermatologie (Heidelb) 77(2): 73-79, 2026 (online 2025). doi: 10.1007/s00105-025-05617-7

Papadopoulou M, Ramachandran H, Binder S, Hildebrandt B, Rossi A^#, Krutmann J^#: CRISPR/Cas9-mediated editing of XPA in induced pluripotent stem cells: A model for investigating Xeroderma Pigmentosum and NER dysfunction. Stem Cell Res 89: 103869, 2025. doi: 10.1016/j.scr.2025.103869

Passeron T, Liu W, Morita A, Goh CL, Alexis A, Dreno B, Kang HY, Ly F, Puig S, Schalka S, Candiani JO, Demessant A, Le Floc’h C, Kerob D, Krutmann J, Lim HW: Pigmentary disorders around the world: Self-reported prevalence and impact on quality of life and social stigmatization. J Invest Dermatol 146(6): 1661-1668.e5, 2025. doi: 10.1016/j.jid.2025.10.598

Rolfes MK, Singh N, Haarmann-Stemmann T, Krutmann J: The toxin of the year: Airborne PM_2.5. Dermatitis 37(3): 329-346, 2026. doi: 10.1177/17103568251385571

Krutmann J, Brown A, Passeron T, Granger C, Gilaberte Y, Trullas C, Piquero-Casals J, Leone G, Schalka S, Lim HW: PINGing sunshine: A review of the evidence for adding non-filtering photoprotective ingredients to sunscreens. Photodermatol Photoimmunol Photomed 41(6): e70062, 2025. doi: 10.1111/phpp.70062

Brown A, Passeron T, Granger C, Gilaberte Y, Trullas C, Piquero-Casals J, Leone G, Schalka S, Lim HW, Krutmann J: Ingredients for oral photoprotection: An evidence-based classification. J Am Acad Dermatol 94(2): 699-703, 2026 (online 2025). doi: 10.1016/j.jaad.2025.10.062

Li Z, Li S, Han C, Chen Y, Zhen H, Sun Y, Zhou X, Chen Y, Zheng Y, Han L, Krutmann J, Nie C, Wang J, Xia J: A comprehensive reference catalog of human skin DNA virome reveals novel viral diversity and microenvironmental influences. Microbiol Spectr e0117825, 2025. doi: 10.1128/spectrum.01178-25

Passeron T, Liu W, Morita A, Goh CL, Alexis A, Dreno B, Kang HY, Ly F, Puig S, Schalka S, Ocampo Candiani J, Demessant-Flavigny AL, Le Floc’h C, Kerob D, Krutmann J, Lim H, Taieb C, Ezzedine K: Stigmatization in patients with pigmentation disorders: the ISPOT study. Clin Exp Dermatol 51(1): 124-127, 2025. doi: 10.1093/ced/llaf381

Lichtenberg S, Vinnenberg L, Steffen F, Plegge I, Hanuscheck N, Dobelmann V, Gruchot J, Schroeter CB, Ramachandran H, Wasser B, Bachir D, Nelke C, Franz J, Riethmüller C, Tenzer S, Distler U, Vogelaar CF, Kusche-Vihrog K, Skryabin BV, Rozhdestvensky TS, Schwab A, Krutmann J, Rossi A, Budde T, Bittner S, Meuth SG, Ruck T: The potassium channel K2P2.1 shapes the morphology and function of brain endothelial cells via actin network remodeling. Nat Commun 16(1): 6622, 2025. doi: 10.1038/s41467-025-61816-9

Jaenicke T, Zhang T, Proksch E, Krutmann J, Luger T: Sensitive skin syndrome in the Chinese population – A critical discussion of current knowledge, clinical implications, and research needs. Exp Dermatol 34(6): e70124, 2025. doi: 10.1111/exd.70124

Liu Q, Wu J, Wang N, Burki C, Grether-Beck S, Krutmann J: A French maritime pine bark extract alleviates cellulite: A double-blinded, randomized, placebo-controlled clinical study. Phytomed Plus 5(3): 100821, 2025. doi: 10.1016/j.phyplu.2025.100821

Hartung F, Krutmann J, Haarmann-Stemmann T: Evidence that the aryl hydrocarbon receptor orchestrates oxinflammatory responses and contributes to airborne particulate matter-induced skin aging. Free Radic Biol Med 233: 264-278, 2025. doi: 10.1016/j.freeradbiomed.2025.03.040

Lim HW, Piquero-Casals J, Schalka S, Leone G, Trullàs C, Brown A, Foyaca M, Gilaberte Y, Krutmann J, Passeron T: Photoprotection in pregnancy: addressing safety concerns and optimizing skin health. Front Med 12: 1563369, 2025. doi: 10.3389/fmed.2025.1563369

Melzer N, Meuth SG, Barbaric I, Krutmann J, Rossi A: SPRINGing forward: Advancing RNA editing efficiency and precision with engineered ADAR2. Mol Ther Nucleic Acids 36(2): 102517, 2025. doi: 10.1016/j.omtn.2025.102517

Passeron T, Lim H, Krutmann J, Dreno B, Abdulla S, Ting P, Li M, Chemani N, Kerob D, Le Floch C, Dayeh NR: Here comes the sun! A study on sun exposure and associated risks in the Canadian population. J Cutan Med Surg 29(2_suppl): 3S-12S, 2025. doi: 10.1177/12034754251322778

Brown A, Passeron T, Granger C, Gilaberte Y, Trullas C, Piquero-Casals J, Leone G, Schalka S, Lim HW, Krutmann J: An evidence-driven classification of non-filtering ingredients for topical photoprotection. Br J Dermatol 192(6): 1132-1134, 2025. doi: 10.1093/bjd/ljaf055

Singh N, Wigmann C, Vijay P, Phuleria HC, Kress S, Majmudar G, Kong R, Krutmann J, Schikowski T: Combined effect of ambient temperature and relative humidity on skin aging phenotypes in the era of climate change: Results from an Indian cohort study. Dermatitis 36(1):72-79, 2025 (online 2024). doi: 10.1089/derm.2024.0301

Passeron T, Dreno B, Puig S, Goh CL, Kang HY, Ly F, Morita A, Candiani JO, Schalka S, Wei L, Demessant-Flavigny A-L, Le Floc’h C, Kerob D, Lim HW, Krutmann J: Sun exposure behaviors and knowledge among the at-risk population: Results from an international survey, the HELIOS project. Photodermatol Photoimmunol Photomed 40(6): e13014, 2024. doi: 10.1111/phpp.13014

Dobner J, Diecke S, Krutmann J, Prigione A, Rossi A: Reassessment of marker genes in human induced pluripotent stem cells for enhanced quality control. Nat Commun 15(1):8547, 2024. doi: 10.1038/s41467-024-52922-1

Chen H, Chen Y, Zhou Y, Cao S, Lu J, Han L, Worzfeld T, Krutmann J, Wang J, Xia J: Optimizing skin surface metabolomics: A comprehensive evaluation of sampling methods, extraction solvents, and analytical techniques. J Invest Dermatol S0022-202X(24)02105-5, 2024. doi: 10.1016/j.jid.2024.08.027

Xia J-j, Zhong Q, Li Z-m, Wei Q-z., Jiang L-y, Duan C, Jia H-j, Tan Y-m, Han L-y, Krutmann J, Wang J, Liu X: Culture dependent and independent approaches reveal the role of specific bacteria in human skin aging. iMetaOmics e26, 2024. doi:10.1002/imo2.26

Lim HW, Passeron T, Goh CL, Kang HY, Ly F, Morita A, Ocampo-Candiani J, Puig S, Schalka S, Wei L, Demessant AL, Le Floc’h C, Kerob D, Dreno B, Krutmann J: Evaluating the frequency of mole checks by a dermatologist and correlated variables in a global survey across 17 Countries: HELIOS Project. Acta Derm Venereol 104:adv40929, 2024. doi: 10.2340/actadv.v104.40929

Kapr J, Scharkin I, Ramachandran H, Westhoff P, Pollet M, Dangeleit S, Brockerhoff G, Rossi A, Koch K, Krutmann J, Fritsche E: HiPSC-derived 3D neural models reveal neurodevelopmental pathomechanisms of the Cockayne Syndrome B. Cell Mol Life Sci 81(1):368, 2024. doi: 10.1007/s00018-024-05406-w

Sant’Anna-Silva ACB, Botton T, Rossi A, Dobner J, Bzioueche H, Thach N, Blot L, Pagnotta S, Kleszczynski K, Steinbrink K, Mazure NM, Rocchi S, Krutmann J, Passeron T, Tulic MK: Vitiligo auto-immune response upon oxidative stress-related mitochondrial DNA release opens up new therapeutic strategies. Clin Transl Med 14(8): e1810, 2024. doi: 10.1002/ctm2.1810

Dreno B, Passeron T, Puig S, Lim HW, Goh CL, Kang HY, Ly F, Morita A, Ocampo-Candiani J, Schalka S, Wei L, Demessant AL, Le Floc’h C, Kerob D, Krutmann J: Are people more concerned about photoaging than skin cancer when raising awareness about risks of skin exposure? Clin Exp Dermatol 50(7): 1423-1424, 2025 (online 2024). doi: 10.1093/ced/llae225

Gilaberte Y, Piquero-Casals J, Schalka S, Leone G, Brown A, Trullàs C, Jourdan E, Lim HW, Krutmann J, Passeron T: Exploring the impact of solar radiation on skin microbiome to develop improved photoprotection strategies. Photochem Photobiol 2024. doi: 10.1111/php.13962

Morita A, Lim HW, Passeron T, Goh CL, Kang HY, Ly F, Ocampo-Candiani J, Puig S, Schalka S, Wei L, Demessant AL, Le Floc’h C, Kerob D, Dreno B, Krutmann J: Attitudes and behaviors regarding sun exposure in Japan compared to Europe and North America. J Dermatol 1(7): 1004-1009, 2024. doi: 10.1111/1346-8138.17217

Fehsel K, Bouvier M-L, Capobianco L, Lunetti P, Klein B, Oldiges M, Majora M, Löffler S: Neuroreceptor inhibition by Clozapine triggers mitohormesis and metabolic reprogramming in human blood cells. Cells 13(9): 762, 2024. doi: 10.3390/cells13090762

Loerch C, Szepanowski LP, Reiss J, Adjaye J and Graffmann N: Forskolin induces FXR expression and enhances maturation of iPSC-derived hepatocyte-like cells. Front Cell Dev Biol 12: 1383928, 2024. doi: 10.3389/fcell.2024.1383928

Passeron T, Dreno B, Puig S, Goh CL, Kang HY, Ly F, Morita A, Ocampo Candiani J, Schalka S, Wei L, Demessant-Flavigny AL, Le Floc’h C, Kerob D, Lim HW, Krutmann J: Outdoor workers and sun exposure: Results of an international survey on sun exposure behaviours and knowledge among 17 countries, the HELIOS project. J Eur Acad Dermatol Venereol, 2024. doi: 10.1111/jdv.20001

Szepanowski LP, Wruck W, Kapr J, Rossi A, Fritsche E, Krutmann J, Adjaye J: Cockayne syndrome patient iPSC-derived brain organoids and neurospheres show early transcriptional dysregulation of biological processes associated with brain development and metabolism. Cells 13(7): 591, 2024. doi: 10.3390/cells13070591

Dobner J, Nguyen T, Pavez-Giani MG, Cyganek L, Distelmaier F, Krutmann J, Prigione A, Rossi A: mtDNA Analysis using Mitopore. Mol Ther Methods Clin Dev 32(2): 101231, 2024. doi: 10.1016/j.omtm.2024.101231

Zhang R, Pu W, Zhang X, Di Y, Xu J, Zhu M, Tan Y, Liu W, Krutmann J, Wang J, Ma Y: Blue light protection factor: a method to assess the protective efficacy of cosmetics against blue light-induced skin damage in the Chinese population. Photochem Photobiol Sci 23(4): 711-718, 2024. doi: 10.1007/s43630-024-00546-1

Granger C, Trullàs C, Sokeechand NB, Jourdan E, Krutmann J, Francois-Newton V, Hosenally M: Evaluating the factors influencing sun protection factors (SPF): Pooling data from multiple studies involving two reference ISO 24444:2019 sunscreen products (P2 and P8). Photodermatol Photoimmunol Photomed 40:e12942, 2024. doi:10.1111/phpp.12942

Passeron T, Lim HW, Goh CL, Kang HY, Ribeyre C, Demessant-Flavigny AL, Le Floc’h C, Kerob D, Krutmann J, Comte C, Dreno B, Leccia MT: Thirty years of promoting sun safety in France: The messages are heard but not followed! J Eur Acad Dermatol Venereol 38(4): e306-e309, 2024. doi: 10.1111/jdv.19543

Passeron T, Lim HW, Goh CL, Kang HY, Ly F, Morita A, Ocampo-Candiani J, Puig S, Schalka S, Liu W, Demessant AL, Le Floc’h C, Kerob D, Dreno B, Krutmann J: Do regrets of parents about sun overexposure impact preventive measures applied on their children? J Eur Acad Dermatol Venereol 38: e199-e203, 2024. doi: 10.1111/jdv.19556

Krutmann J, Grether-Beck S, Makrantonaki E, Schikowski T: Hautalterungsexposom. Dermatologie 2023. doi: 10.1007/s00105-023-05210-w

Passeron T, Lim HW, Goh CL, Kang HY, Ly F, Morita A, Ocampo-Candiani J, Puig S, Schalka S, Liu W, Demessant-Flavigny AL, Le Flo’ch C, Kerob D, Dreno B, Krutmann J: Sun exposure behaviours as a compromise to paradoxical injunctions: Insight from a worldwide survey. J Eur Acad Dermatol Venereol 37: 2481-2489, 2023. doi: 10.1111/jdv.19421

Marini A, Aue N, Jaenicke T, Grether-Beck S, Trullas C, Granger C, Jourdan E, Krutmann J: Assessment of the protective effect against air pollution-induced skin pigmentation of an oral nutritional supplement containing antioxidants: A randomized, double-blinded, placebo-controlled study. J Eur Acad Dermatol Venereol 37(9): e1183-e1186, 2023. doi: 10.1111/jdv.19183

Piquero-Casals J, Morgado-Carrasco D, Rozas-Muñoz E, Mir-Bonafé JF, Trullàs C, Jourdan E, Piquero-Martin J, Zouboulis CC, Krutmann J: Sun exposure, a relevant exposome factor in acne patients and how photoprotection can improve outcomes. J Cosmet Dermatol 22(6): 1919-1928, 2023. doi: 10.1111/jocd.15726

Granger C, Passeron T, Trullas C, Hosenally M, Sokeechand BN, Krutmann J, Lim HW: Outdoor clinical testing with reference sunscreens to determine differences in skin response between populations of different ethnicity: A combined data analysis from 128 subjects. Photodermatol Photoimmunol Photomed, 39(5): 419-427, 2023. doi: 10.1111/phpp.12871

Na J, Li N, Yan L, Schikowski T, Ye R, Krutmann J, Li Z: Skin aging associated with chromium among rural housewives in northern China. Ecotoxicol Environ Saf 253: 114676, 2023. doi: 10.1016/j.ecoenv.2023.114676

Clahsen T, Hadrian K, Notara M, Schlereth SL, Howaldt A, Prokosch V, Volatier T, Hos D, Schroedl F, Kaser-Eichberger A, Heindl LM, Steven P, Bosch JJ, Steinkasserer A, Rokohl AC, Liu H, Mestanoglu M, Kashkar H, Schumacher B, Kiefer F, Schulte-Merker S, Matthaei M, Hou Y, Fassbender S, Jantsch J, Zhang W, Enders P, Bachmann B, Bock F, Cursiefen C: The novel role of lymphatic vessels in the pathogenesis of ocular diseases. Prog Retin Eye Res 96: 101157, 2023. doi: 10.1016/j.preteyeres.2022.101157

Cai C, Zeng B, Lin L, Zheng M, Burki C, Grether-Beck S, Krutmann J: An oral French maritime pine bark extract improves hair density in menopausal women: A randomized, placebo-controlled, double blind intervention study. Health Sci Rep 6(1): e1045, 2023. doi: 10.1002/hsr2.1045

Peng Q, Liu Y, Huels A, Zhang C, Yu Y, Qiu W, Cai X, Zhao Y, Schikowski T, Merches K, Liu Y, Yang Y, Wang J, Zhao Y, Jin L, Zhang L, Krutmann J, Wang S: Genetic variants in Telomerase Reverse Transcriptase contribute to solar lentigines. J Invest Dermatol 143(6): 1062-1072, 2023 (online 2022). doi: 10.1016/j.jid.2022.11.016 (*equal contribution)

Vogeley C, Kress S, Lang D, Vogel CFA, Hartung F, Brenden H, Nakamura M, Grether-Beck S, Rossi A, Krutmann J, Schikowski T, Haarmann-Stemmann T: A gene variant of AKR1C3 contributes to interindividual susceptibilities to atopic dermatitis triggered by particulate air pollution. Allergy 78(5): 1372-1375, 2023 (online 2022). doi: 10.1111/all.15622 (*equal contribution)

Sondermann NC, Faßbender S, Hartung F, Hätälä AM, Rolfes KM, Vogel CFA, Haarmann-Stemmann T: Functions of the aryl hydrocarbon receptor (AHR) beyond the canonical AHR/ARNT signaling pathway. Biochem Pharmacol 208: 115371, 2023 (online 2022). doi: 10.1016/j.bcp.2022.115371

Wigmann C, Hüls A, Krutmann J, Schikowski T: Estimating the relative contribution of environmental and genetic risk factors to different aging traits by combining correlated variables into weighted risk scores. Int J Environ Res Public Health 19(24): 16746, 2022. doi: 10.3390/ijerph192416746

Liu W, Krutmann J, Tian Y, Granger C, Piquero-Casals J, Trullàs C, Passeron T, Lim HW, Lai W: Commentary: Facial aesthetic dermatological procedures and photoprotection in Chinese populations. Dermatol Ther (Heidelb) 13(1): 13-27, 2023 (online 2022). doi: 10.1007/s13555-022-00862-3

Krutmann J, Piquero-Casals J, Morgado-Carrasco D, Granger C, Trullàs C, Passeron T, Lim HW: Photoprotection for people with skin of colour: needs and strategies. Br J Dermatol 188(2): 168-175, 2023 (online 2022). doi: 10.1093/bjd/ljac046

Chen H, Zhao Q, Zhong Q, Duan C, Krutmann J, Wang, J, Xia J: Skin microbiome, metabolome and skin phenome, from the perspectives of skin as an ecosystem. Phenomics 2: 363–382, 2022. doi: 10.1007/s43657-022-00073-y

Granger C, Petkar G, Hosenally M, Bustos J, Trullàs C, Passeron T, Krutmann J: Evaluation of a sunscreen product compared with reference standards P3, P5 and P8 in outdoor conditions: A randomized, double-blinded, intra-individual study in healthy subjects. Dermatol Ther (Heidelb) 12(11): 2531-2546, 2022. doi: 10.1007/s13555-022-00815-w

Krutmann J: Environmental Dermatitis. Dermatitis 33(5): 305. 2022. doi: 10.1097/DER.0000000000000944

Stermann T, Nguyen T, Stahlmecke B, Todea AM, Woeste S, Hacheney I, Krutmann J, Unfried K, Schins RPF, Rossi A: Carbon nanoparticles adversely affect CFTR expression and toxicologically relevant pathways. Sci Rep 12(1): 14255, 2022. doi: 10.1038/s41598-022-18098-8

Vogeley C, Nguyen T, Woeste S, Krutmann J, Haarmann-Stemmann T, Rossi A: Rapid and simple analysis of short and long sequencing reads using Duesselpore^TM. Front Genet 13: 931996, 2022. doi: 10.3389/fgene.2022.931996

Wei Q, Li Z, Gu Z, Liu X, Krutmann J, Wang J, Xia J: Shotgun metagenomic sequencing reveals skin microbial variability from different facial sites. Front Microbiol 13: 933189, 2022. doi: 10.3389/fmicb.2022.933189

Plitta-Michalak B, Stricker N, Pavez Loriè E, Chen I, Pollet M, Krutmann J, Volkmer B, Greinert R, Boukamp P, Rapp A: Development and characterisation of an irradiation device for biomedical studies covering the solar spectrum with individual regulated spectral bands. Photochem Photobiol Sci 21(9): 1701-1717, 2022. doi: 10.1007/s43630-022-00252-w

Duteil L, Queille-Roussel C, Aladren S, Bustos X, Trullas C, Granger C, Krutmann J, Passeron T: Prevention of polymorphic light eruption afforded by a very high broad-spectrum protection sunscreen containing Ectoin. Dermatol Ther (Heidelb) 12(7): 1603-1613, 2022. doi: 10.1007/s13555-022-00755-5

Nguyen T, Ramachandran H, Martins S, Krutmann J, Rossi A: Identification of genome edited cells using CRISPRnano. Nucleic Acids Res 50(W1): W199–203, 2022. doi: 10.1093/nar/gkac440

Surber C, Krutmann J: Sonnenschutz: Wichtiger denn je! [Sun protection measures: more important than ever!]. Hautarzt 73(4): 249-250, 2022. doi: 10.1007/s00105-022-04964-z

Wolf P, Krutmann J: Sonnenschutz der Zukunft: Herausforderungen und Möglichkeiten [Sunscreens of the future: challenges and opportunities]. Hautarzt 73(4): 257-265, 2022. doi: 10.1007/s00105-022-04959-w

Vogeley C, Rolfes KM, Krutmann J, Haarmann-Stemmann T: The aryl hydrocarbon receptor in the pathogenesis of environmentally-induced squamous cell carcinomas of the skin. Front Oncol 12: 841721, 2022. doi: 10.3389/fonc.2022.841721

Liu W, Jie L, Liu D, Makino ET, Krutmann J, Mehta RC: Protective effects of a day/night dual-antioxidant serum on skin: A randomized, regimen-controlled study in Chinese women exposed to air pollution. J Cosmet Dermatol 22(1): 245-254, 2023. doi: 10.1111/jocd.14839

Neves JR, Grether-Beck S, Krutmann J, Correia P, Gonçalves JE Jr, Sant’Anna B, Kerob D: Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs. J Cosmet Dermatol 21(10): 4462-4469, 2022. doi: 10.1111/jocd.14837

Li B, Cheng Y, Tan Y, Wang F, Hu W, Wang X, Liu W, Krutmann J, Wang S, Zou Y: Analysis of factors influencing skin reactions to sunscreens, skin whitening products, and deodorants: Results from a large-scale patch test dataset in China. J Cosmet Dermatol 21(9): 3986-3992, 2022 (online 2021). doi: 10.1111/jocd.14699

Greinert R, Krutmann J: Ultraviolette Strahlung. In: Wichmann HE, Fromme H (Hrsg.): Handbuch der Umweltmedizin, Kap. VII–2.2, 71. Erg.-Lfg. ecomed Medizin, Landsberg

Vogeley C, Sondermann NC, Woeste S, Momin AA, Gilardino V, Hartung F, Heinen M, Maaß SK, Mescher M, Pollet M, Rolfes KM, Vogel CFA, Rossi A, Lang D, Arold ST, Nakamura M, Haarmann-Stemmann T: Unraveling the differential impact of PAHs and dioxin-like compounds on AKR1C3 reveals the EGFR extracellular domain as a critical determinant of the AHR response. Environ Int 158: 106989, 2022 (online 2021). doi: 10.1016/j.envint.2021.106989

Piquero-Casals J, Morgado-Carrasco D, Granger C, Trullàs C, Jesús-Silva A, Krutmann J: Urea in dermatology. A review of its emollient, moisturizing, keratolytic, skin barrier enhancing and antimicrobial properties. Dermatol Ther (Heidelb) 11(6): 1905-1915, 2021. doi: 10.1007/s13555-021-00611-y

Faßbender S, Sondenheimer K, Majora M, Schindler J, Opitz FV, Pollet M, Haarmann-Stemmann T, Krutmann J, Weighardt H: Keratinocytes counteract UVB-induced immunosuppression in mice via HIF1a signaling. J Invest Dermatol 142(4):1183-1193, 2022 (online 2021). doi: 10.1016/j.jid.2021.07.185

Rolfes KM, Sondermann NC, Vogeley C, Dairou J, Gilardino V, Wirth R, Meller S, Homey B, Krutmann J, Lang D, Nakamura M, Haarmann-Stemmann T: Inhibition of 6-formylindolo[3,2-b]carbazole metabolism sensitizes keratinocytes to UVA-induced apoptosis: Implications for vemurafenib-induced phototoxicity. Redox Biol 46: 102110, 2021. doi: 10.1016/j.redox.2021.102110

Grether-Beck S, Marini A, Jaenicke T, Brenden H, Felsner I, Aue N, Brynjolfsdottir A, Krutmann J: Blue Lagoon Algae improve uneven skin pigmentation: Results from in vitro studies and from a monocentric, randomized, double-blind, vehicle-controlled, split-face study. Skin Pharmacol Physiol 35(2): 77-86, 2022 (online 2021). doi: 10.1159/000518781

Breuckmann P, Meinke MC, Jaenicke T, Krutmann J, Rasulev U, Keck CM, Müller RH, Klein AL, Lademann J, Patzelt A: Influence of nanocrystal size on the in vivo absorption kinetics of caffeine after topical application. Eur J Pharm Biopharm 167: 57-64, 2021. doi: 10.1016/j.ejpb.2021.07.006

Li B, Cheng Y, Tan Y, Wang F, Hu W, Wang X, Liu W, Krutmann J, Wang S, Zou Y: Analysis of factors influencing patch test reactions: Results from a large- population-based study in Chinese. J Cosmet Dermatol 21(5): 2183-2188, 2022 (online 2021). doi: 10.1111/jocd.14338

Martins S, Hacheney I, Teichweyde N, Hildebrandt B, Krutmann J, Rossi A: Generation of an induced pluripotent stem cell line (IUFi001) from a Cockayne syndrome patient carrying a mutation in the ERCC6 gene. Stem Cell Res 55: 102456, 2021. doi: 10.1016/j.scr.2021.102456

Passeron T, Zouboulis CC, Tan J, Andersen ML, Katta R, Lyu X, Aguilar L, Kerob D, Morita A, Krutmann J, Peters EMJ: Adult skin acute stress responses to short-term environmental and internal aggression from exposome factors. J Eur Acad Dermatol Venereol 35(10): 1963-1975, 2021. doi: 10.1111/jdv.17432

Granger C, Ong G, Andres P, Trullàs C, Hosenally M, Lai W, Liu W, Krutmann J, Passeron T, Lim HW: Outdoor sunscreen testing with high-intensity solar exposure in a Chinese and Caucasian population. Photodermatol Photoimmunol Photomed 38(1): 19-28, 2022 (online 2021). doi: 10.1111/phpp.12710

Krutmann J, Granger C, Trullàs C, Passeron T: Daily photoprotection: What does it really mean? Photodermatol Photoimmunol Photomed 37(6): 569-570, 2021. doi: 10.1111/phpp.12707

Lim H, Kohli I, Granger C, Trullas C, Piquero-Casals J, Narda M, Masson P, Krutmann J, Passeron T: Photoprotection of the skin from visible light-induced pigmentation: Current testing methods and proposed harmonization. J Invest Dermatol 141(11): 2569-2576, 2021. doi: 10.1016/j.jid.2021.03.012

Grether-Beck S, Felsner I, Brenden H, Marini A, Jaenicke T, Aue N, Welss T, Uthe I, Krutmann J: Air pollution-induced tanning of human skin. Br J Dermatol 185(5): 1026-1034, 2021. doi: 10.1111/bjd.20483

Budden T, Gaudy-Marqueste C, Porter A, Kay E, Gurung S, Earnshaw CH, Roeck K, Craig S, Traves V, Krutmann J, Muller P, Motta L, Zanivan S, Malliri A, Furney SJ, Nagore E, Virós A: Ultraviolet light-induced collagen degradation inhibits melanoma invasion. Nat Commun 12(1): 2742, 2021. doi: 10.1038/s41467-021-22953-z

Klose J, Pahl M, Bartmann K, Bendt F, Blum J, Dolde X, Förster N, Holzer AK, Hübenthal U, Keßel HE, Koch K, Masjosthusmann S, Schneider S, Stürzl LC, Woeste S, Rossi A, Covaci A, Behl M, Leist M, Tigges J, Fritsche E: Neurodevelopmental toxicity assessment of flame retardants using a human DNT in vitro testing battery. Cell Biol Toxicol 38(5): 781-807, 2022 (online 2021). doi: 10.1007/s10565-021-09603-2

Baswan SM, Klosner AE, Weir C, Salter-Venzon D, Gellenbeck KW, Leveret J, Krutmann J: Role of ingestible carotenoids in skin protection: A review of clinical evidence. Photodermatol Photoimmunol Photomed 37(6): 490-504, 2021. doi: 10.1111/phpp.12690

Ramachandran H, Martins S, Kontarakis Z, Krutmann J, Rossi A: Fast but not furious: a streamlined selection method for genome edited cells. Life Sci Alliance 4(6): e202101051, 2021. doi: 10.26508/lsa.202101051

Krutmann J, Schalka S, Watson REB, Liu W, Morita A: Daily photoprotection to prevent photoaging. Photodermatol Photoimmunol Photomed 37(6): 482-489, 2021. doi: 10.1111/phpp.12688

Zhao H, Wu J, Wang N, Grether-Beck S, Krutmann J, Wei L: Oral Pycnogenol® intake benefits the skin in urban Chinese outdoor workers: A randomized, placebo-controlled, double blind, and crossover intervention study. Skin Pharmacol Physiol 34: 135-145, 2021. doi: 10.1159/000514323

Passeron T, Lim HW, Goh CL, Kang HY, Ly F, Morita A, Ocampo Candiani J, Puig S, Schalka S, Wei L, Dréno B, Krutmann J: Photoprotection according to skin phototype and dermatoses: Practical recommendations from an expert panel. J Eur Acad Dermatol Venereol 35(7): 1460-1469, 2021. doi: 10.1111/jdv.17242

Haarmann-Stemmann T, Sutter TR, Krutmann J, Esser C: The mode of action of tapinarof may not only depend on the activation of cutaneous aryl hydrocarbon receptor signaling but also on its antimicrobial activity. J Am Acad Dermatol 85(1): e33-e34, 2021. doi: 10.1016/j.jaad.2021.01.103

Li Z, Xia J, Jiang L, Tan Y, An Y, Zhu X, Ruan J, Chen Z, Zhen H, Ma Y, Jie Z, Xiao L, Yang H, Wang J, Kristiansen K, Xu X, Jin L, Nie C, Krutmann J, Liu X, Wang J: Characterization of the human skin resistome and identification of two microbiota cutotypes. Microbiome* 9(1): 47, 2021. doi: 10.1186/s40168-020-00995-7 (*equal contribution)

Krutmann J, Schikowski T, Morita A, Berneburg M: Environmentally-induced (extrinsic) skin aging: Exposomal factors and underlying mechanisms. J Invest Dermatol 141(4S): 1096-1103, 2021. doi: 10.1016/j.jid.2020.12.011

Krutmann J, Berneburg M: Photodermatologie. Hautarzt 72(1): 1, 2021. doi: 10.1007/s00105-020-04746-5

Krutmann J, Berneburg M: Lichtalterung (Photoaging) der Haut: Was gibt es Neues? Hautarzt 72(1): 2-5, 2021 (online 2020). doi: 10.1007/s00105-020-04747-4

Passeron T, Krutmann J, Andersen ML, Katta R, Zouboulis CC: Clinical and biological impact of the exposome on the skin. J Eur Acad Dermatol Venereol 34 (Suppl 4): 4-25, 2020. doi: 10.1111/jdv.16614

Baswan SM, Marini A, Klosner AE, Jaenicke T, Leverett J, Murray M, Gellenbeck KW, Krutmann J: Orally administered mixed carotenoids protect human skin against ultraviolet A-induced skin pigmentation: A double-blind, placebo-controlled, randomized clinical trial. Photodermatol Photoimmunol Photomed 36(3): 219-225, 2020. doi: 10.1111/phpp.12541

Tan Y, Wang F, Fan G, Yan Z, Li B, Li N, Liu Y, Wang X, Liu W, Krutmann J, Zou Y, Wang S: Identification of factors associated with minimal erythema dose variations in a large-scale population study of 22 146 subjects. J Eur Acad Dermatol Venereol 34(7): 1595-1600, 2020. doi: 10.1111/jdv.16206

Lademann J, Richter H, Patzelt A, Meinke MC, Gross I, Grether-Beck S, Krutmann J, Frazier L, Darvin ME: Laser scanning microscopy for control of skin decontamination efficacy from airborne particulates using highly absorbent textile nanofiber material in combination with PEG-12 dimethicone. Skin Res Technol 26(4): 558-563, 2020. doi: 10.1111/srt.12830

Altuğ H, Fuks KB, Hüls A, Mayer AK, Tham R, Krutmann J, Schikowski T: Air pollution is associated with depressive symptoms in elderly women with cognitive impairment. Environ Int 136: 105448, 2020. doi: 10.1016/j.envint.2019.105448

Krutmann J, Passeron T, Gilaberte Y, Granger C, Leone G, Narda M, Schalka S, Trullas C, Masson P, Lim HW: Photoprotection of the future: Challenges and opportunities. J Eur Acad Dermatol Venereol 34(3): 447-454, 2020. doi: 10.1111/jdv.16030