Publikationen 2020

Originalarbeiten

Peters A, Rospleszcz S, Greiser KH, Dallavalle M, Berger K; Complete list of authors available under: Collaborators. The impact of the COVID-19 pandemic on self-reported health. Dtsch Arztebl Int 117(50): 861-867, 2020. doi: 10.3238/arztebl.2020.0861

Brinkmann V, Schiavi A, Shaik A, Puchta DR, Ventura N: Dietary and environmental factors have opposite AhR-dependent effects on C. elegans healthspan. Aging (Albany NY) 13(1): 104-133, 2020. doi: 10.18632/aging.202316

Vargas-Toscano A, Nickel A-C, Li G, Kamp MA, Muhammad S, Leprivier G, Fritsche E, Barker RA, Sabel M, Steiger HJ, Zhang W, Hänggi D, Kahlert UD: Rapalink-1 targets glioblastoma stem cells and acts synergistically with tumor treating fields to reduce resistance against temozolomide. Cancers 12(12): 3859, 2020. doi: 10.3390/cancers12123859

Fischer I, Nickel A-C, Qin N, Taban K, Pauck D, Steiger H-J, Kamp M, Muhammad S, Hänggi D, Fritsche E, Remke M, Kahlert UD: Different calculation strategies are congruent in determining chemotherapy resistance of brain tumors in vitro. Cells 9(12): 2689, 2020. doi: 10.3390/cells9122689

Nothdurft S, Thumser-Henner C, Breitenbücher F, Okimoto RA, Dorsch M, Opitz CA, Sadik A, Esser C, Hölzel M, Asthana S, Forster J, Beisser D, Kalmbach S, Grüner BM, Bivona TG, Schramm A, Schuler M: Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis. Oncogenesis 9(11): 102, 2020. doi: 10.1038/s41389-020-00286-8

Dahlem C, Kado SY, He F, Bein K, Wu D, Haarmann-Stemmann T, Kado NY, Vogel CF: AHR signaling interacting with nutritional factors regulating the expression of markers in vascular inflammation and atherogenesis. Int J Mol Sci 21(21): 8287, 2020. doi: 10.3390/ijms21218287

Tsiampali J, Neumann S, Giesen B, Koch K, Maciaczyk D, Janiak C, Hänggi D, Maciaczyk J: Enzymatic activity of CD73 modulates invasion of gliomas via epithelial-mesenchymal transition-like reprogramming. Pharmaceuticals 13(11): 378, 2020. doi: 10.3390/ph13110378

Kolling J, Tigges J, Hellack B, Albrecht C, Schins RP: Evaluation of the NLRP3 inflammasome activating effects of a large panel of TiO2 nanomaterials in macrophages. Nanomaterials 10(9): 1876, 2020. doi: 10.3390/nano10091876

Pavez-Lorie E, Stricker N, Plitta-Michalak B, Peng-Chen I, Volkmer B, Greinert R, Jauch A, Boukamp P, Rapp, A: Characterisation of the novel spontaneously immortalized and invasively growing human skin keratinocyte line HaSKpw. Sci Rep 10: 15196, 2020. doi: 10.1038/s41598-020-71315-0

Pemp D, Geppert LN, Wigmann C, Kleider C, Hauptstein R, Schmalbach K, Ickstadt K, Esch HL, Lehmann L: Influence of breast cancer risk factors and intramammary biotransformation on estrogen homeostasis in the human breast. Arch Toxicol 94(9): 3013-3025, 2020. doi: 10.1007/s00204-020-02807-1

Feng X, Flexeder C, Markevych I, Standl M, Heinrich J, Schikowski T, Koletzko S, Herberth G, Bauer CP, von Berg A, Berdel D, Astell-Burt T: Impact of residential green space on sleep quality and sufficiency in children and adolescents residing in Australia and Germany. Int J Environ Res Public Health 17(13): 4894, 2020. doi: 10.3390/ijerph17134894

Hippe A, Braun SA, Oláh P, Gerber PA, Schorr A, Seeliger S, Hotz S, Jannasch K, Pivarci A, Buhren B, Schrumpf H, Kislat A, Bünemann E, Steinhoff M, Fischer J, Lira SA, Boukamp P, Hevezi P, Stoecklein NH, Hoffmann T, Alves F, Sleeman J, Bauer T, Klufa J, Amberg N, Sibilia M, Zlotnik A, Müller-Homey A, Homey B: EGFR/Ras-induced CCL20 production modulates the tumour microenvironment. Br J Cancer 123: 942-954, 2020. doi: 10.1038/s41416-020-0943-2

Negele L, Flexeder C, Koletzko S, Bauer CP, von Berg A, Berdel D, Schikowski T, Standl M, Peters A, Schulz H: Association between objectively assessed physical activity and sleep quality in adolescence. Results from the GINIplus and LISA studies. Sleep Med 72: 65-74, 2020. doi: 10.1016/j.sleep.2020.03.007

Wahle T, Sofranko A, Dekkers S, Miller MR; Heusinkveld HJ, Albrecht C, Cassee FR, Schins RPF: Evaluation of neurological effects of cerium dioxide nanoparticles doped with different amounts of zirconium following inhalation exposure in mouse models of Alzheimer’s and vascular disease. Neurochem Int 138: 104755, 2020. doi: 10.1016/j.neuint.2020.104755

Kämpfer AAM, Busch M, Schins RPF: Advanced in vitro testing strategies and models of the intestine for nanosafety research. Chem Res Toxicol 33(5): 1163-1178, 2020. doi: 10.1021/acs.chemrestox.0c00079

Abramson MJ, Wigmann C, Altug H, Schikowski T: Ambient air pollution is associated with airway inflammation in older women: a nested cross-sectional analysis. BMJ Open Respir Res 7: e000549, 2020. doi: 10.1136/bmjresp-2019-000549

Baswan SM, Marini A, Klosner AE, Jaenicke T, Leverett J, Murray M, Gellenbeck KW, Krutmann J: Orally administered mixed carotenoids protect human skin against ultraviolet A-induced skin pigmentation: A double-blind, placebo-controlled, randomized clinical trial. Photodermatol Photoimmunol Photomed 36(3): 219-225, 2020. doi: 10.1111/phpp.12541

Häselbarth L, Ouwens DM, Teichweyde N, Hochrath K, Merches K, Esser C: The small chain fatty acid butyrate antagonizes the TCR-stimulation-induced metabolic shift in murine epidermal gamma delta T cells. EXCLI J 19: 334-350, 2020. doi: 10.17179/excli2020-1123

Madhusudhan N, Pausan MR, Halwachs B, Durdević M, Windisch M, Kehrmann J, Patra V, Wolf P, Boukamp P, Moissl-Eichinger C, Cerroni L, Becker JC, Gorkiewicz G: Molecular profiling of keratinocyte skin tumors links Staphylococcus aureus overabundance and increased human β-Defensin-2 expression to growth promotion of squamous cell carcinoma. Cancers (Basel) 12(3): 541, 2020. doi: 10.3390/cancers12030541

Boots AW, Veith C, Albrecht C, Bartholome R, Drittij MJ, Claessen SMH, Bast A, Rosenbruch M, Jonkers L, van Schooten FJ, Schins RPF: The dietary antioxidant quercetin reduces hallmarks of bleomycin-induced lung fibrogenesis in mice. BMC Pulm Med 20: 112, 2020. doi: 10.1186/s12890-020-1142-x

Nimtz L, Hartmann J, Tigges J, Masjosthusmann S, Schmuck M, Keßel E, Theiss S, Köhrer K, Petzsch P, Adjaye J, Wigmann C, Wieczorek D, Hildebrandt B, Bendt F, Hübenthal U, Brockerhoff G, Fritsche E: Characterization and application of electrically active neuronal networks established from human induced pluripotent stem cell-derived neural progenitor cells for neurotoxicity evaluation. Stem Cell Res 45: 101761, 2020. doi: 10.1016/j.scr.2020.101761

Pavez Loriè E, Boukamp P: Methods in cell biology: Cell-derived matrices. Methods Cell Biol 156: 309-332, 2020. doi: 10.1016/bs.mcb.2019.11.012

Merches K, Schiavi A, Weighardt H, Steinwachs S, Teichweyde N, Förster I, Hochrath K, Schumak B, Ventura N, Petzsch P, Köhrer K, Esser C: AHR signaling dampens inflammatory signature in neonatal skin γδ T cells. Int J Mol Sci 21(6): 2249, 2020. doi: 10.3390/ijms21062249

Wang Q, Zhao Q, Wang G, Wang B, Zhang Y, Zhang J, Li N, Zhao Y, Qiao H, Li W, Liu X, Liu L, Wang F, Zhang Y, Guo Y: The association between ambient temperature and clinical visits for inflammation-related diseases in rural areas in China. Environ Pollut 261: 114128, 2020. doi: 10.1016/j.envpol.2020.114128

Schikowski T*, Wigmann C*, Fuks KB*, et al.: Blutdruckmessung in der NAKO – methodische Unterschiede, Blutdruckverteilung und Bekanntheit der Hypertonie im Vergleich zu anderen bevölkerungsbezogenen Studien in Deutschland. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 63(4): 452-464, 2020. doi: 10.1007/s00103-020-03109-8 (* equal contribution)

weitere Beiträge zur NAKO im Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz:

March 2020, issue 3: Die Basiserhebung der NAKO Gesundheitsstudie – Teil I: Erste Ergebnisse zu sozialen und medizinischen Faktoren

April 2020, issue 4: Die Basiserhebung der NAKO Gesundheitsstudie – Teil II: Erste Ergebnisse zu häufigen Volkskrankheiten

Altuğ H, Fuks KB, Hüls A, Mayer AK, Tham R, Krutmann J, Schikowski T: Air pollution is associated with depressive symptoms in elderly women with cognitive impairment. Environ Int 136: 105448, 2020. doi: 10.1016/j.envint.2019.105448

Tan Y, Wang F, Fan G, Yan Z, Li B, Li N, Liu Y, Wang X, Liu W, Krutmann J, Zou Y, Wang S: Identification of factors associated with minimal erythema dose (MED) variations in a large-scale population study of 22,146 subjects. J Eur Acad Dermatol Venereol 34(7): 1595-1600, 2020. doi: 10.1111/jdv.16206

Lademann J, Richter H, Patzelt A, Meinke MC, Gross I, Grether-Beck S, Krutmann J, Frazier L, Darvin ME: Laser scanning microscopy for control of skin decontamination efficacy from airborne particulates using highly absorbent textile nanofiber material in combination with PEG-12 dimethicone. Skin Res Technol 26(4): 558-563, 2020. doi: 10.1111/srt.12830

Uhlmann C, Kuhn LM, Tigges J, Fritsche E, Kahlert DU: Efficient modulation of TP53 expression in human induced pluripotent stem cells. Curr Protoc Stem Cell Biol 52(1): e102, 2020. doi: 10.1002/cpsc.102

Thyssen JP, Ahluwalia TS, Paternoster L, Ballardini N, Bergström A, Melén E, Chawes B, Stokholm J, Hourihane JO, O'Sullivan DM, Bager P, Maelbye M, Bustamante M, Torrent M, Esplugues A, Duijts L, Hu C, Elbert NJ, Pasmans SGMA, Nijsten TEC, von Berg A, Standl M, Schikowski T, Herberth G, Heinrich J, Lee YA, Marenholz I, Lau S, Curtin JA, Simpson A, Custovic A, Pennell CE, Wang CA, Holt PG, Bisgaard H, Bønnelykke K: Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis. Allergy 75(6): 1481-1485, 2020. doi: 10.1111/all.14162

Mekic S, Hamer MA, Wigmann C, Gunn DA, Kayser M, Jacobs LC, Schikowski T, Nijsten T, Pardo LM: Epidemiology and determinants of facial telangiectasia: a cross-sectional study. J Eur Acad Dermatol Venereol 34(4): 821-826, 2020. doi: 10.1111/jdv.15996

Grether-Beck S, Marini A, Jaenicke T, Goessens-Rück P, McElwee KJ, Hoffmann R, Krutmann J: Autologous cell therapy for aged human skin: a randomized, placebo-controlled, phase-I study. Skin Pharmacol Physiol 33: 9-16, 2020. doi: 10.1159/000502240

Trullàs C, Granger C, Lim HW, Krutmann J, Masson P: Linear and exponential sunscreen behaviours as an explanation for observed discrepancies in sun protection factor testing. Photodermatol Photoimmunol Photomed 36(5): 351-356, 2020. doi: 10.1111/phpp.12500