Core Unit Modellentwicklung - Publikationen


Dobner J, Ramachandran H, Rossi A: Genome editing in translational medicine: An inventory. Front Biosci (Landmark Ed) 27(8): 241, 2022. doi: 10.31083/j.fbl2708241

Busch M, Bredeck G, Waag F, Rahimi K, Ramachandran H, Bessel T, Barcikowski S, Herrmann A, Rossi A, Schins RPF: Assessing the NLRP3 inflammasome activating potential of a large panel of micro- and nanoplastics in THP-1 cells. Biomolecules 12(8): 1095, 2022. doi: 10.3390/biom12081095

Stermann T, Nguyen T, Stahlmecke B, Todea AM, Woeste S, Hacheney I, Krutmann J, Unfried K, Schins RPF, Rossi A: Carbon nanoparticles adversely affect CFTR expression and toxicologically relevant pathways. Sci Rep 12(1): 14255, 2022. doi: 10.1038/s41598-022-18098-8

Vogeley C, Nguyen T, Woeste S, Krutmann J, Haarmann-Stemmann T, Rossi A: Rapid and simple analysis of short and long sequencing reads using DuesselporeTM. Front Genet 13: 931996, 2022. doi: 10.3389/fgene.2022.931996

Busch M, Ramachandran H, Wahle T, Rossi A, Schins RPF: Investigating the role of the NLRP3 inflammasome pathway in acute intestinal inflammation: use of THP-1 knockout cell lines in an advanced triple culture model. Front Immunol 13: 898039, 2022. doi: 10.3389/fimmu.2022.898039

Nguyen T, Ramachandran H, Martins S, Krutmann J, Rossi A: Identification of genome edited cells using CRISPRnano. Nucleic Acids Res, 2022. doi: 10.1093/nar/gkac440

Uhlmann C, Nickel AC, Picard D, Rossi A, Li G, Hildebrandt B, Brockerhoff G, Bendt F, Hübenthal U, Hewera M, Steiger HJ, Wieczorek D, Perrakis A, Zhang W, Remke M, Koch K, Tigges J, Croner RS, Fritsche E, Kahlert UD: Progenitor cells derived from gene-engineered human induced pluripotent stem cells as synthetic cancer cell alternatives for in vitro pharmacology. Biotechnol J 17(6): e2100693, 2022. doi: 10.1002/biot.202100693

Martins S, Erichsen L, Datsi A, Wruck W, Goering W, Chatzantonaki E, de Amorim VCM, Rossi A, Chrzanowska KH, Adjaye J: Impaired p53-mediated DNA damage response contributes to microcephaly in Nijmegen Breakage Syndrome patient-derived cerebral organoids. Cells 11(5): 802, 2022. doi: 10.3390/cells11050802

Rossi A, Lickfett S, Martins S, Prigione A: A call for consensus guidelines on monitoring the integrity of nuclear and mitochondrial genomes in human pluripotent stem cells. Stem Cell Rep 17(4): 707-710, 2022. doi: 10.1016/j.stemcr.2022.01.019


Rossi A, Kontarakis Z: Beyond Mendelian inheritance: genetic buffering and phenotype variability. Phenomics 2: 79–87, 2022. doi: 10.1007/s43657-021-00030-1

Vogeley C, Sondermann NC, Woeste S, Momin AA, Gilardino V, Hartung F, Heinen M, Maaß SK, Mescher M, Pollet M, Rolfes KM, Vogel CFA, Rossi A, Lang D, Arold ST, Nakamura M, Haarmann-Stemmann T: Unraveling the differential impact of PAHs and dioxin-like compounds on AKR1C3 reveals the EGFR extracellular domain as a critical determinant of the AHR response. Environ Int 158: 106989, 2022. doi: 10.1016/j.envint.2021.106989

Martins S, Hacheney I, Teichweyde N, Hildebrandt B, Krutmann J, Rossi A: Generation of an induced pluripotent stem cell line (IUFi001) from a Cockayne syndrome patient carrying a mutation in the ERCC6 gene. Stem Cell Res 55: 102456, 2021. doi: 10.1016/j.scr.2021.102456

Klose J, Pahl M, Bartmann K, Bendt F, Blum J, Dolde X, Förster N, Holzer A-K, Hübenthal U, Keßel HE, Koch K, Masjosthusmann S, Schneider S, Stürzl L-C, Woeste S, Rossi A, Covaci A, Behl M, Leist M, Tigges J, Fritsche E: Neurodevelopmental toxicity assessment of flame retardants using a human DNT in vitro testing battery. Cell Biol Toxicol, 2021. doi: 10.1007/s10565-021-09603-2

Tigges J, Bielec K, Brockerhoff G, Hildebrandt B, Hübenthal U, Kapr J, Koch K, Teichweyde N, Wieczorek D, Rossi A, Fritsche E: Academic application of Good Cell Culture Practice for induced pluripotent stem cells. ALTEX 38(4): 595-614, 2021. doi: 10.14573/altex.2101221

Ramachandran H, Martins S, Kontarakis Z, Krutmann J, Rossi A: Fast but not furious: a streamlined selection method for genome edited cells. Life Sci Alliance 4(6): e202101051, 2021. doi: 10.26508/lsa.202101051

Vogel CFA, Lazennec G, Kado SY, Dahlem C, He Y, Castaneda A, Ishihara Y, Vogeley C, Rossi A, Haarmann-Stemmann T, Jugan J, Mori H, Borowsky AD, La Merrill MA, Sweeney C: Targeting the aryl hydrocarbon receptor signaling pathway in breast cancer development. Front Immunol 12: 62534, 2021. doi: 10.3389/fimmu.2021.625346


El-Brolosy MA, Kontarakis Z, Rossi A, Kuenne C, Günther S, Fukuda N, Kikhi K, Boezio GLM, Takacs CM, Lai SL, Fukuda R, Gerri C, Giraldez AJ, Stainier DYR: Genetic compensation triggered by mutant mRNA degradation. Nature 568(7751): 193-197, 2019. doi: 10.1038/s41586-019-1064-z