2022
Vogeley C, Rolfes KM, Krutmann J, Haarmann-Stemmann T: The Aryl Hydrocarbon Receptor in the pathogenesis of environmentally-induced squamous cell carcinomas of the skin. Front Oncol 12: 841721, 2022. doi: 10.3389/fonc.2022.841721
Ishihara Y, Kado SY, Bein KJ, He Y, Pouraryan AA, Urban A, Haarmann-Stemmann T, Sweeney C and Vogel CFA: Aryl hydrocarbon receptor signaling synergizes with TLR/NF-κB-signaling for induction of IL-22 through canonical and non-canonical AhR pathways. Front Toxicol 3: 787360, 2022. doi: 10.3389/ftox.2021.787360
Fehsel K, Schwanke K, Kappel BA, Fahimi E, Meisenzahl-Lechner E, Esser C, Hemmrich K, Haarmann-Stemmann T, Kojda G, Lange-Asschenfeldt C: Activation of the aryl hydrocarbon receptor by clozapine induces preadipocyte differentiation and contributes to endothelial dysfunction. J Psychopharmacol 36(2): 191-201, 2022. doi: 10.1177/02698811211055811
2021
Vogeley C, Sondermann NC, Woeste S, Momin AA, Gilardino V, Hartung F, Heinen M, Maaß SK, Mescher M, Pollet M, Rolfes KM, Vogel CFA, Rossi A, Lang D, Arold ST, Nakamura M, Haarmann-Stemmann T: Unraveling the differential impact of PAHs and dioxin-like compounds on AKR1C3 reveals the EGFR extracellular domain as a critical determinant of the AHR response. Environ Int 158: 106989, 2022. doi: 10.1016/j.envint.2021.106989
Faßbender S, Sondenheimer K, Majora M, Schindler J, Opitz FV, Pollet M, Haarmann-Stemmann T, Krutmann J, Weighardt H: Keratinocytes counteract UVB-induced immunosuppression in mice via HIF1a signaling. J Invest Dermatol 142(4):1183-1193, 2022. doi: 10.1016/j.jid.2021.07.185
Rolfes KM, Sondermann NC, Vogeley C, Dairou J, Gilardino V, Wirth R, Meller S, Homey B, Krutmann J, Lang D, Nakamura M, Haarmann-Stemmann T: Inhibition of 6-formylindolo[3,2-b]carbazole metabolism sensitizes keratinocytes to UVA-induced apoptosis: Implications for vemurafenib-induced phototoxicity. Redox Biol 46: 102110, 2021. doi: 10.1016/j.redox.2021.102110
Vogel CFA, Lazennec G, Kado SY, Dahlem C, He Y, Castaneda A, Ishihara Y, Vogeley C, Rossi A, Haarmann-Stemmann T, Jugan J, Mori H, Borowsky AD, La Merrill MA, Sweeney C: Targeting the aryl hydrocarbon receptor signaling pathway in breast cancer development. Front Immunol 12: 62534, 2021. doi: 10.3389/fimmu.2021.625346
Haarmann-Stemmann T, Sutter TR, Krutmann J, Esser C: The mode of action of tapinarof may not only depend on the activation of cutaneous aryl hydrocarbon receptor signaling but also on its antimicrobial activity. J Am Acad Dermatol 85(1): e33-e34, 2021. doi: 10.1016/j.jaad.2021.01.103
Fritsche E, Haarmann-Stemmann T, Kapr J, Galanjuk S, Hartmann J, Mertens PR, Kämpfer AAM, Schins RPF, Tigges J, Koch K: Stem cells for next level toxicity testing in the 21st century. Small 17(15): e2006252, 2021. doi: 10.1002/smll.202006252
Ghashghaei O, Pedrola M, Seghetti F, Martin VV, Zavarce R, Babiak M, Novacek J, Hartung F, Rolfes KM, Haarmann-Stemmann T, Lavilla R: Extended multicomponent reactions with indole aldehydes: Access to unprecedented polyheterocyclic scaffolds, ligands of the Aryl Hydrocarbon Receptor. Angew Chem Int Edit 60(5): 2603-2608, 2021. doi: 10.1002/anie.202011253