Aktuelle Publikationen


Coppari S, Colomba M, Fraternale D, Brinkmann V, Romeo M, Rocchi MBL, Di Giacomo B, Mari M, Guidi L, Ramakrishna S, Ventura N, Albertini MC: Antioxidant and anti-inflammaging ability of prune (Prunus Spinosa L.) extract result in improved wound healing efficacy. Antioxidants 10(3): 374, 2021. doi: 10.3390/antiox10030374

Sofranko A, Wahle T, Heusinkveld HJ, Stahlmecke B, Dronov M, Pijnenburg D, Hilhorst R, Lamann K, Albrecht C, Schins RPF: Evaluation of the neurotoxic effects of engineered nanomaterials in C57BL/6J mice in 28-day oral exposure studies. Neurotoxicology 84: 155-171, 2021. doi: 10.1016/j.neuro.2021.03.005

Tacu I, Kokalari I, Abollino O, Albrecht C, Malandrino M, Ferretti AM, Schins RPF, Fenoglio I: Mechanistic insights into the role of iron, copper and carbonaceous component on the oxidative potential of ultrafine particulate matter. Chem Res Toxicol 34(3): 767-779, 2021. doi: 10.1021/acs.chemrestox.0c00399

Vogel CFA, Lazennec G, Kado SY, Dahlem C, He Y, Castaneda A, Ishihara Y, Vogeley C, Rossi A, Haarmann-Stemmann T, Jugan J, Mori H, Borowsky AD, La Merrill MA, Sweeney C: Targeting the aryl hydrocarbon receptor signaling pathway in breast cancer development. Front Immunol 12: 62534, 2021. doi: 10.3389/fimmu.2021.625346

Distler T, Lauria I, Detsch R, Sauter CM, Bendt F, Kapr J, Rütten S, Boccaccini AR, Fritsche E: Neuronal differentiation from induced pluripotent stem cell-derived neurospheres by the application of oxidized alginate-gelatin-laminin hydrogels. Biomedicines 9(3): 261, 2021. doi: 10.3390/biomedicines9030261

Li Z*, Xia J*, Jiang L, Tan Y, An Y, Zhu X, Ruan J, Chen Z, Zhen H, Ma Y, Jie Z, Xiao L, Yang H, Wang J, Kristiansen K, Xu X, Jin L, Nie C, Krutmann J*, Liu X*, Wang J*: Characterization of the human skin resistome and identification of two microbiota cutotypes. Microbiome 9(1): 47, 2021. doi: 10.1186/s40168-020-00995-7 (*equal contribution)

Zhao Q, Kress S, Markevych I, Berdel D, von Berg A, Gappa M, Koletzko S, Bauer CP, Schulz H, Standl M, Heinrich J, Schikowski T: Long-term air pollution exposure under European Union limits and adolescents' lung function: Modifying effect of abnormal weight in the GINIplus and LISA birth cohorts. Chest 2021. doi: 10.1016/j.chest.2021.02.007

Haarmann-Stemmann T, Sutter TR, Krutmann J, Esser C: The mode of action of tapinarof may not solely depend on the activation of cutaneous aryl hydrocarbon receptor signaling but also on its antimicrobial activity. J Am Acad Dermatol 2021. doi: 10.1016/j.jaad.2021.01.103

Zhao H, Wu J, Wang N, Grether-Beck S, Krutmann J, Wei L: Oral Pycnogenol® intake benefits skin in urban Chinese outdoor workers: A randomized, placebo-controlled, double blind, cross-over intervention study. Skin Pharmacol Physiol 2021. doi: 10.1159/000514323

Llewellyn SV, Kämpfer AAM, Keller JG, Vilsmeier K, Büttner V, Seleci DA, Schins RPF, Doak SH, Wohlleben W: Simulating nanomaterial transformation in cascaded biological compartments to enhance the physiological relevance of in vitro dosing regimes: Optional or required? Small 17(15): e2004630, 2021. doi: 10.1002/smll.202004630

Kämpfer AAM, Busch B, Büttner V, Bredeck G, Stahlmecke B, Hellack B, Masson I, Albrecht C, Schins RP: Model complexity as determining factor for in vitro nanosafety studies – Effects of silver and titanium dioxide nanomaterials in intestinal models. Small 17(15): e2004223, 2021. doi: 10.1002/smll.202004223

Lambert KA, Markevych I, Yang B-Y, Bauer C-P, Berdel D, von Berg A, Bergmann K-C, Lodge C, Koletzko S, Prendergast LA, Schikowski T, Schulz H, Werchan M, Heinrich J, Standl M, Erbas B: Association of early life and acute pollen exposure with lung function and exhaled nitric oxide (FeNO). A prospective study up to adolescence in the GINIplus and LISA cohort. Sci Total Environ 763: 143006, 2021. doi: 10.1016/j.scitotenv.2020.143006

Barenys M, Illa M, Hofrichter M, Loreiro C, Pla L, Klose J, Kühne BA, Gómez-Catalán J, Braun JM, Crispi F, Gratacós E, Fritsche E: Rabbit neurospheres as a novel in vitro tool for studying neurodevelopmental effects induced by intrauterine growth restriction. Stem Cells Transl Med 10(2): 209-221, 2021. doi: 10.1002/sctm.20-0223

Mekic S, Wigmann C, Gunn DA, Kayser M, Jacobs LC, Schikowski T, Nijsten T, Pardo LM: Genetics of facial telangiectasia in the Rotterdam study; a genome-wide association study and candidate gene approach. J Eur Acad Dermatol Venereol 35(3): 749-754, 2021. doi: 10.1111/jdv.17014

Ghashghaei O, Pedrola M, Seghetti F, Martin VV, Zavarce R, Babiak M, Novacek J, Hartung F, Rolfes KM, Haarmann-Stemmann T, Lavilla R:  Extended multicomponent reactions with indole aldehydes: Access to unprecedented polyheterocyclic scaffolds, ligands of the Aryl Hydrocarbon Receptor. Angew Chem Int Edit 60(5): 2603-2608, 2021. doi: 10.1002/anie.202011253

Melén E, Standl M, Gehring U, Altug H, Antó JM, Berdel D, Bergström A, Bousquet J, Heinrich J, Koppelman GH, Kull I, Lupinek C, Markevych I, Schikowski T, Thiering E, Valenta R, van Hage M, von Berg A, Vonk JM, Wickman M, Wijga A, Gruzieva O: Air pollution and IgE sensitization in 4 European birth cohorts - the MeDALL project. J Allergy Clin Immunol 47(2): 713-722, 2021. doi: 10.1016/j.jaci.2020.08.030

Busch M, Bredeck G, Kämpfer AAM, Schins RPF: Investigations of acute effects of polystyrene and polyvinyl chloride micro- and nanoplastics in an advanced in vitro triple culture model of the healthy and inflamed intestine. Environ Res 193: 110536, 2021. doi: 10.1016/j.envres.2020.110536

Strom A, Strassburger K, Schmuck M, Shevalye H, Davidson E, Zivehe F, Bönhof G, Reimer R, Belgardt BF, Fleming T, Biermann B, Burkart V, Müssig K, Szendroedi J, Yorek MA, Fritsche E, Nawroth PP, Roden M, Ziegler D; GDS Group: Interaction between magnesium and methylglyoxal in diabetic polyneuropathy and neuronal models. Mol Metab 43: 101114, 2021. doi: 10.1016/j.molmet.2020.101114

Zhao Q, Kress S, Markevych I, Berdel D, von Berg A, Gappa M, Koletzko S, Bauer CP, Schulz H, Standl M, Heinrich J, Schikowski T: Air pollution during infancy and lung function development into adolescence: The GINIplus/LISA birth cohorts study. Environ Int 146: 106195, 2021. doi: 10.1016/j.envint.2020.106195

Klose J, Tigges J, Masjosthusmann S, Schmuck K, Bend F, Hübenthal U, Petzsch P, Köhrer K, Koch K, Fritsche E: TBBPA targets converging key events of human oligodendrocyte development resulting in two novel AOPs. ALTEX 2021. doi: 10.14573/altex.2007201

Übersichtsarbeiten, Buchbeiträge u.a.

Annesi-Maesano I, Forastiere F, Balmes J, Garcia E, Harkema J, Holgate S, Kelly F, Khreis H, Hoffmann B, Maesano CN, McConnell R, Peden D, Pinkerton K, Schikowski T, Thurston G, Van Winkle LS, Carlsten C: The clear and persistent impact of air pollution on chronic respiratory diseases: a call for interventions. Eur Respir J 57(3): 2002981, 2021. doi: 10.1183/13993003.02981-2020

Esser C: Trajectory shifts in interdisciplinary research of the aryl hydrocarbon receptor - a personal perspective on thymus and skin. Int J Mol Sci 22(4): 1844, 2021. doi: 10.3390/ijms22041844

Neuhaus W*: Consensus statement from the European Network of 3R centres (EU3Rnet). ALTEX 38(1): 138-139, 2021. doi: 10.14573/altex.2010061 *Neuhaus has submitted the Consensus Statement on behalf of all participating centres, institutes and societies of EU3Rnet

Passeron T, Lim HW, Goh CL, Kang HY, Ly F, Morita A, Ocampo Candiani J, Puig S, Schalka S, Wei L, Dréno B, Krutmann J: Photoprotection according to skin phototype and dermatoses: Practical recommendations from an expert panel. J Eur Acad Dermatol Venereol 2021. doi: 10.1111/jdv.17242

Krutmann J, Schikowski T, Morita A, Berneburg M: Environmentally-induced (extrinsic) skin aging: Exposmal factors and underlying mechanisms. J Invest Dermatol 141(4S): 1096-1103, 2021. doi: 10.1016/j.jid.2020.12.011

Tham R, Schikowski T: The role of traffic-related air pollution on neurodegenerative diseases in older people: An epidemiological perspective. J Alzheimers Dis 79(3): 949-959, 2021. doi: 10.3233/JAD-200813

Krutmann J, Berneburg M: Photodermatologie. Hautarzt 72(1): 1, 2021. doi: 10.1007/s00105-020-04746-5

Krutmann J, Berneburg M: Lichtalterung (Photoaging) der Haut: Was gibt es Neues? Hautarzt 72(1): 2-5, 2021. doi: 10.1007/s00105-020-04747-4

Fritsche E, Haarmann-Stemmann T, Kapr J, Galanjuk S, Hartmann J, Mertens PR, Kämpfer AAM, Schins RPF, Tigges J, Koch K: Stem cells for next level toxicity testing in the 21st century. Small 17(15): e2006252, 2021. doi: 10.1002/smll.202006252