Borror MB, Girotti M, Kar A, Cain MK, Gao X, MacKay VL, Herron B, Bhaskaran S, Becerra S, Novy N, Ventura N, Johnson TE, Kennedy BK, Rea SL: Inhibition of ATR reverses a mitochondrial respiratory insufficiency. Cells 11(11): 1731, 2022. doi: 10.3390/cells11111731
Tuesday, 24 May 2022
by Jana Freytag
New models for rare diseases provide new insights
Monday, 23 May 2022
by Christiane Klasen
A team of scientists from the Medical Faculty of the Heinrich Heine University Düsseldorf (HHU) and the IUF – Leibniz Research Institute for Environmental Medicine in Düsseldorf developed a multicellular model for human neurometabolic diseases associated with mitochondrial complex I deficiency and identified a potential therapeutic compound as well as its underlying mechanism. The results
- Published in Press
Larigot L, Bui LC, de Bouvier M, Pierre O, Pinon G, Fiocca J, Ozeir M, Tourette C, Ottolenghi C, Imbeaud S, Pontoizeau C, Blaise BJ, Chevallier A, Tomkiewicz C, Legrand B, Elena-Herrmann B, Néri C, Brinkmann V, Nioche P, Barouki R, Ventura N, Dairou J, Coumoul X: Identification of modulators of the C. elegans aryl hydrocarbon receptor and characterization of transcriptomic and metabolic AhR-1 profiles. Antioxidants (Basel) 11(5): 1030, 2022. doi: 10.3390/antiox11051030
Monday, 23 May 2022
by Jana Freytag
Maglioni S, Schiavi A, Melcher M, Brinkmann V, Luo Z, Laromaine A, Raimundo N, Meyer JN, Distelmaier F, Ventura N: Neuroligin-mediated neurodevelopmental defects are induced by mitochondrial dysfunction and prevented by lutein in C. elegans. Nat Commun 13: 2620, 2022. doi: 10.1038/s41467-022-29972-4
Thursday, 12 May 2022
by Jana Freytag
Greimel E, Adams L, Zsigo C, Berdel D, von Berg A, Koletzko S, Bauer CP, Schikowski T, Herberth G, Heinrich J, Schulte-Körne G, Standl M: Psychopathological symptoms as precursors of depressive symptoms in adolescence: a prospective analysis of the GINIplus and LISA birth cohort studies. Soc Psychiatry Psychiatr Epidemiol 57(8): 1627-1639, 2022. doi: 10.1007/s00127-022-02267-1
Friday, 15 April 2022
by Jana Freytag
Tanabe S, Beaton D, Chauhan V, Choi I, Danielsen PH, Delrue N, Esterhuizen M, Filipovska J, FitzGerald R, Fritsche E, Gant T, Garcia-Reyero N, Helm J, Huliganga E, Jacobsen N, Kay JE, Kim YJ, Klose J, La Rocca C, Luettich K, Mally A, O’Brien J, Poulsen SS, Rudel RA, Sovadinova I, Tollefsen KE, Vogel U, Yepiskoposyan H, Yauk C: Report of the 1st and 2nd Mystery of Reactive Oxygen Species conferences. ALTEX 39(2): 336-338, 2022. doi: 10.14573/altex.2203011
Monday, 11 April 2022
by Jana Freytag
Marb A, Libuda L, Standl M, Koletzko S, Bauer CP, Schikowski T, Berdel D, von Berg A, Herberth G, Bühlmeier J, Harris CP: Obesogenic eating behaviour and dietary intake in German children and adolescents: results from the GINIplus and LISA birth cohort studies. Eur J Clin Nutr 76(10): 1478-1485, 2022. doi: 10.1038/s41430-022-01125-2
Friday, 01 April 2022
by Jana Freytag