FF2 Archive

Brown A, Passeron T, Granger C, Gilaberte Y, Trullas C, Piquero-Casals J, Leone G, Schalka S, Lim HW, Krutmann J: Ingredients for oral photoprotection: An evidence-based classification. J Am Acad Dermatol 94(2): 699-703, 2026. doi: 10.1016/j.jaad.2025.10.062

Brown A, Passeron T, Gilaberte Y, Piquero-Casals J, Schalka S, Simonetto C, Foyaca M, Lim HW, Krutmann J: Biological Photoprotection: A Review of its Mechanisms, Evidence, and Clinical Implications. Dermatol Ther (Heidelb) 16(7): 3633-3648, 2026. doi: 10.1007/s13555-026-01805-y

Brown A, Passeron T, Gilaberte Y, Piquero-Casals J, Schalka S, Simonetto C, Foyaca M, Lim HW, Krutmann J: Biological...

Ntzani E R, Ramachandran H, Papadopoulou M, Binder S, Hildebrandt B, Haarmann-Stemmann T, Rossi A: CRISPR/Cpf1-mediated knockout of FLG in human induced pluripotent stem cells generates a model for studying epidermal barrier dysfunction. Stem Cell Res 2026. doi: 10.1016/j.scr.2026.104056

Busch M, Bredeck G, Bouwmeester H, Schins RPF: NLRP3 inflammasome activation by particles and fibers: implications for human hazard assessment. Arch Toxicol 2026. doi: 10.1007/s00204-026-04477-x

Xia J, Kuzyakov Y, Krutmann J: Microbial diversity as a proxy for skin health: an ecological framework misapplied. Br J Dermatol 2026. doi: 10.1093/bjd/ljag251

Xia J, Kuzyakov Y, Krutmann J: Microbial diversity as a proxy for skin health: an ecological framework misapplied. B...

Krutmann J, Puig S, Dreno B, Ocampo Candiani J, Ly F, Schalka S, Wei L, Morita A, Goh CL, Kang HY, Demessant-Flavigny AL, Taieb C, Le Floc’h C, Kerob D, Lim HW, Alexis A, Passeron T: Prevalence and impact of solar lentigines: an international survey. J Eur Acad Dermatol Venereol 2026. doi: 10.1111/jdv.70522

Hartung F, Dairou J, Ramamoorthy S, Rolfes KM, Meller S, Haarmann-Stemmann T: Erlotinib and leflunomide disrupt 6-formylindolo[3,2-b]carbazole metabolism and sensitize keratinocytes to UVA radiation-induced apoptosis. Photodermatol Photoimmunol Photomed 42(4): e70099, 2026. doi: 10.1111/phpp.70099

Ramachandran H, Dobner J, Nguyen T, Binder S, Tolle I, Vykhlyantseva I, Krutmann J, Miccio A, Staerk C, Brusson M, Kontarakis Z, Prigione A, Rossi A: CleanFinder: a scalable framework for comprehensive genome editing analysis. Trends Biotechnol 2026. doi: 10.1016/j.tibtech.2026.04.024

Anarat A, Krutmann J, Schwender H: A nonparametric statistical method for deconvolving densities in the analysis of proteomic data. BMC Bioinformatics 27(1): 83, 2026. doi: 10.1186/s12859-026-06408-0

Lim HW, Schalka S, Trautinger F, Baptista MS, Chien AL, Cole C, Gilaberte Y, González S, Hamzavi I, Krutmann J, Kohli I, Osterwalder U, Rodrigues M, Passeron T: International modified Delphi consensus statement on visible light photoprotection: Effects, measurement, and recommendations. J Invest Dermatol 2026. doi: 10.1016/j.jid.2026.03.012

Wu Q, Klinkhammer H, Kunwar K, Staerk C, Maj C, Mayr A: Detecting gene–environment interactions to guide personalized intervention: Boosting distributional regression for polygenic scores. Proc Natl Acad Sci USA 123(14): e2529164123, 2026. doi: 10.1073/pnas.2529164123

Piquero-Casals J, Bertold C, Alomar A, Morgado-Carrasco D, Gilaberte Y, López-Estebaranz JL, Massa A, de Castro CS, Leone G, Lim HW, Krutmann J, Ezzedine K, Passeron T: Exposome risk factors for vitiligo: A systematic evidence review. Am J Clin Dermatol 2026. doi: 10.1007/s40257-026-01012-7

Passeron T, Lim HW, Goh CL, Kang HY, Ly F, Morita A, Ocampo-Candiani J, Puig S, Schalka S, Wei L, Demessant AL, Taïeb C, Le Floc’h C, Kerob D, Krutmann J: Patterns of regret for inadequate sun protection: A population-based study [HELIOS]. J Eur Acad Dermatol Venereol 40(8): e706-e708, 2026. doi: 10.1111/jdv.70385

Dimmers F, Reichert D, Nguyen T, Lück N, Ramachandran H, Bremges A, Schild J, Humbek M, Grether-Beck S, Rossi A, Staerk C, Esser C, Krutmann J: Monocentric, vehicle-controlled, double-blind study to assess the short- and long-term effects of a Ceramide NP C15-containing emollient on the skin microbiome and the skin barrier function in sensitive skin. Skin Pharmacol Physiol 27: 1-18, 2026. doi: 10.1159/000551043

Singh N, Schikowski T, Krutmann J: Air pollution and skin diseases: A systematic review of epidemiological evidence. Am J Clin Dermatol 27(2): 261-276, 2026. doi: 10.1007/s40257-026-01006-5

Wajda A, Ejma-Multański A, Himida D, Stypińska B, Filipowicz G, Rossi A, Hacheney I, Haarmann-Stemmann T, Paradowska-Gorycka A, Esser C: Evidence for a fibrogenic interaction between the aryl hydrocarbon receptor and the Wnt/β-catenin pathways in human keratinocytes and fibroblasts. Cell Physiol Biochem 60(1): 44-62, 2026. doi: 10.33594/000000846

Dimmers F, Reichert D, Wigmann C, Trullàs C, Piquero-Casals J, Brown A, Foyaca M, Esser C, Krutmann J: Effects of solar-simulated (UVB plus UVA) radiation on the skin microbiome: An exploratory study. Photochem Photobiol 2026. doi: 10.1111/php.70078

Krutmann J, Merk HF, Haarmann-Stemmann T: Umweltdermatologie. Dermatologie (Heidelb) 77(2): 71-72, 2026. doi: 10.1007/s00105-025-05629-3

Coumoul X, Barouki R, Esser C, Haarmann-Stemmann T, Lawrence BP, Lehmann J, Moura-Alves P, Murray IA, Opitz CA, Perdew GH, Bourguet W: The aryl hydrocarbon receptor: structure, signaling, physiology and pathology. Signal Transduct Target Ther 11(1): 20, 2026. doi: 10.1038/s41392-025-02500-8

Esser C, Haarmann-Stemmann T: Per- und Polyfluoralkylsubstanzen – die „Ewigkeitschemikalien“ und Haut. Dermatologie (Heidelb) 77(2): 108-113, 2026 (online 2025). doi: 10.1007/s00105-025-05615-9

Dimmers F, Wigmann C, Zhang T, Czech P, Wang S, Krutmann J, Schikowski T: The relationship between sensitive skin and skin aging in Han Chinese. Exp Dermatol 34(12): e70190, 2025. doi: 10.1111/exd.70190

Rolfes KM, Haarmann-Stemmann T, Krutmann J: Auswirkungen partikulärer Luftverschmutzung auf die menschliche Haut. Dermatologie (Heidelb) 77(2): 73-79, 2026 (online 2025). doi: 10.1007/s00105-025-05617-7

Papadopoulou M, Ramachandran H, Binder S, Hildebrandt B, Rossi A^#, Krutmann J^#: CRISPR/Cas9-mediated editing of XPA in induced pluripotent stem cells: A model for investigating Xeroderma Pigmentosum and NER dysfunction. Stem Cell Res 89: 103869, 2025. doi: 10.1016/j.scr.2025.103869

Passeron T, Liu W, Morita A, Goh CL, Alexis A, Dreno B, Kang HY, Ly F, Puig S, Schalka S, Candiani JO, Demessant A, Le Floc’h C, Kerob D, Krutmann J, Lim HW: Pigmentary disorders around the world: Self-reported prevalence and impact on quality of life and social stigmatization. J Invest Dermatol 146(6): 1661-1668.e5, 2025. doi: 10.1016/j.jid.2025.10.598

Rolfes MK, Singh N, Haarmann-Stemmann T, Krutmann J: The toxin of the year: Airborne PM_2.5. Dermatitis 37(3): 329-346, 2026. doi: 10.1177/17103568251385571

Krutmann J, Brown A, Passeron T, Granger C, Gilaberte Y, Trullas C, Piquero-Casals J, Leone G, Schalka S, Lim HW: PINGing sunshine: A review of the evidence for adding non-filtering photoprotective ingredients to sunscreens. Photodermatol Photoimmunol Photomed 41(6): e70062, 2025. doi: 10.1111/phpp.70062

Brown A, Passeron T, Granger C, Gilaberte Y, Trullas C, Piquero-Casals J, Leone G, Schalka S, Lim HW, Krutmann J: Ingredients for oral photoprotection: An evidence-based classification. J Am Acad Dermatol 94(2): 699-703, 2026 (online 2025). doi: 10.1016/j.jaad.2025.10.062

Li Z, Li S, Han C, Chen Y, Zhen H, Sun Y, Zhou X, Chen Y, Zheng Y, Han L, Krutmann J, Nie C, Wang J, Xia J: A comprehensive reference catalog of human skin DNA virome reveals novel viral diversity and microenvironmental influences. Microbiol Spectr e0117825, 2025. doi: 10.1128/spectrum.01178-25

Mykicki N, Eble JA, Weighardt H, Gonnelli E, Schneeweiß M, Esser C, Weishaupt C, Rezaei M, Förster I, Schwab N, Wiendl H, Clausen BE, Meuth SG, Loser K: AhR signaling in skin-resident CD207+ cells is involved in UV-B-induced amelioration of neuroinflammation. Proc Natl Acad Sci U S A 122(36): e2424009122, 2025. doi: 10.1073/pnas.2424009122

Wajda A, Paradowska-Gorycka A, Esser C: Systemic sclerosis and AHR: Shedding light on a hidden connections. Autoimmun Rev 19: 103915, 2025. doi: 10.1016/j.autrev.2025.103915

Passeron T, Liu W, Morita A, Goh CL, Alexis A, Dreno B, Kang HY, Ly F, Puig S, Schalka S, Ocampo Candiani J, Demessant-Flavigny AL, Le Floc’h C, Kerob D, Krutmann J, Lim H, Taieb C, Ezzedine K: Stigmatization in patients with pigmentation disorders: the ISPOT study. Clin Exp Dermatol 51(1): 124-127, 2025. doi: 10.1093/ced/llaf381

Jaenicke T, Zhang T, Proksch E, Krutmann J, Luger T: Sensitive skin syndrome in the Chinese population – A critical discussion of current knowledge, clinical implications, and research needs. Exp Dermatol 34(6): e70124, 2025. doi: 10.1111/exd.70124

Standl M, Budu-Aggrey A, Johnston LJ, Elias MS, Arshad SH, Bager P, Bataille V, Blakeway H, Bønnelykke K, Boomsma D, Brumpton BM, Bustamante Pineda M, Campbell A, Curtin JA, Eliasen A, Fadista JPS, Feenstra B, Gerner T, Medina-Gomez C, Grosche S, Gutzkow KB, Halling AS, Hayward C, Henderson J, Herrera-Luis E, Holloway JW, Hottenga J, O’B Hourihane J, Hu C, Hveem K, Irizar A, Jacquemi B, Jessen L, Kress S, Kurukulaaratchy RJ, Lau S, Llop S, Løset M, Marenholz I, Mason D, McCartney DL, Melbye M, Melén E, Minica C, Murray CS, Nijsten T, Pardo LM, Pasmans S, Pennell CE, Rinnov MR, Santorelli G, Schikowski T, Sheehan D, Simpson A, Söderhäll C, Thomas LF, Thyssen JP, Torrent M, van Beijsterveldt T, Visconti A, Vonk JM, Wang CA, Xu CJ, Ziyab AH; UK Translational Research Network in Dermatology; BIOMAP Consortium; Custovic A, Di Meglio P, Duijts L, Flohr C, Irvine AD, Koppelman GH, Lee YA, Reynolds NJ, Smith C, Langan SM, Paternoster L, Brown SJ: Gene-environment interaction affects risk of atopic eczema: Population and in vitro studies. Allergy 80(8): 2201-2212, 2025. doi: 10.1111/all.16605

Haarmann-Stemmann T, Esser C: “Forever Chemicals” – Cutaneous exposure to per- and polyfluoroalkyl substances (PFAS): Cause for concern? J Invest Dermatol 145(8): 1846-1849, 2025. doi: 10.1016/j.jid.2025.03.030

Liu Q, Wu J, Wang N, Burki C, Grether-Beck S, Krutmann J: A French maritime pine bark extract alleviates cellulite: A double-blinded, randomized, placebo-controlled clinical study. Phytomed Plus 5(3): 100821, 2025. doi: 10.1016/j.phyplu.2025.100821

Nadal Rodríguez P, Hartung F, Pedrola M, Coomar S, Diaz-Moreno A, Hätälä AM, Rolfes KM, Sánchez-Vera I, Gil J, Molins E, Viayna A, Hanzl A, Thomä NH, Haarmann-Stemmann T^#, Luque FJ^#, Lavilla R^#, Ghashghaei O^#: A multicomponent reaction-based platform opens new avenues in aryl hydrocarbon receptor modulation. ACS Cent Sci 11(4): 629-641, 2025. doi: 10.1021/acscentsci.5c00194 (*equal contribution)

Nadal Rodríguez P*, Hartung F*, Pedrola M, Coomar S, Diaz-Moreno A, Hätälä AM, Rolfes KM, Sánchez-Vera I, Gil J, Mol...

Hartung F, Krutmann J, Haarmann-Stemmann T: Evidence that the aryl hydrocarbon receptor orchestrates oxinflammatory responses and contributes to airborne particulate matter-induced skin aging. Free Radic Biol Med 233: 264-278, 2025. doi: 10.1016/j.freeradbiomed.2025.03.040

Lim HW, Piquero-Casals J, Schalka S, Leone G, Trullàs C, Brown A, Foyaca M, Gilaberte Y, Krutmann J, Passeron T: Photoprotection in pregnancy: addressing safety concerns and optimizing skin health. Front Med 12: 1563369, 2025. doi: 10.3389/fmed.2025.1563369

Passeron T, Lim H, Krutmann J, Dreno B, Abdulla S, Ting P, Li M, Chemani N, Kerob D, Le Floch C, Dayeh NR: Here comes the sun! A study on sun exposure and associated risks in the Canadian population. J Cutan Med Surg 29(2_suppl): 3S-12S, 2025. doi: 10.1177/12034754251322778

Wolf K, Dallavalle M, Niedermayer F, Bolte G, Lakes T, Schikowski T, Greiser KH, Schwettmann L, Westerman R, Nikolaou N, Staab J, Wolff R, Stübs G, Rach S, Schneider A, Peters A, Hoffmann B: Environmental exposure assessment in the German National Cohort (NAKO). Environ Res 273: 121259, 2025. doi: 10.1016/j.envres.2025.121259

Haarmann-Stemmann T, Reichert D, Coumoul X, Lawrence BP, Perdew GH, Sherr DH, Weighardt H, Rolfes KM, Esser C: The Janus-facedness of the aryl hydrocarbon receptor pathway Report of the 6th International AHR Meeting: Research, Prevention, Therapy. Biochem Pharmacol 234: 116808, 2025. doi: 10.1016/j.bcp.2025.116808

Brown A, Passeron T, Granger C, Gilaberte Y, Trullas C, Piquero-Casals J, Leone G, Schalka S, Lim HW, Krutmann J: An evidence-driven classification of non-filtering ingredients for topical photoprotection. Br J Dermatol 192(6): 1132-1134, 2025. doi: 10.1093/bjd/ljaf055

Eberle OF, Hartung F, Benndorf P, Haarmann-Stemmann T: Skin sensitizers enhance superoxide formation by polycyclic aromatic hydrocarbons via the aldo-keto reductase pathway. Free Radic Biol Med 230: 50-57, 2025. doi: 10.1016/j.freeradbiomed.2025.02.005

Sondermann NC, Vogel CFA, Haarmann-Stemmann T: Dioxins do not only bind to AHR but also team up with EGFR at the cell-surface: A novel mode of action of toxicological relevance? EXCLI Journal 24: 184–197, 2025. doi: 10.17179/excli2024-8038

Rodriguez FS, Röhr S, Dragano N, Schmidt B, Becher H, Schikowski T, Gastell S, Harth V, Hoven H, Linseisen J, Greiser KH, Leitzmann M, Bohmann P, Castell S, Heise JK, Krist L, Keil T, Karch A, Teismann H, Moreno Velásquez I, Pischon T, Peters A, Führer A, Mikolajczyk R, Günther K, Brand T, Meinke-Franze C, Schipf S, Grabe HJ, Brenner H, Koch-Gallenkamp L, Berger K, Wagner M, Katzke V, Lieb W, Pabst A, Riedel-Heller SG: Low income, being without employment, and living alone: how they are associated with cognitive functioning-Results from the German national cohort (NAKO). Aging Neuropsychol Cogn 32(4): 542-557, 2025 (online 2024). doi: 10.1080/13825585.2024.2438825

Sondermann NC, Momin AA, Arold ST, Haarmann-Stemmann T: Polybrominated diphenyl ether flame retardants inhibit growth factor-induced activation of EGFR by binding to its extracellular domain. Arch Toxicol 99(2):745-753, 2024. doi: 10.1007/s00204-024-03926-9

Singh N, Schikowski T: Interactive effect of genetic and environmental risk factors on Psoriasis: current evidence and future directives. Br J Dermatol 192(3): 374-375, 2024. doi: 10.1093/bjd/ljae450

Singh N, Wigmann C, Vijay P, Phuleria HC, Kress S, Majmudar G, Kong R, Krutmann J, Schikowski T: Combined effect of ambient temperature and relative humidity on skin aging phenotypes in the era of climate change: Results from an Indian cohort study. Dermatitis 36(1):72-79, 2025 (online 2024). doi: 10.1089/derm.2024.0301

Passeron T, Dreno B, Puig S, Goh CL, Kang HY, Ly F, Morita A, Candiani JO, Schalka S, Wei L, Demessant-Flavigny A-L, Le Floc’h C, Kerob D, Lim HW, Krutmann J: Sun exposure behaviors and knowledge among the at-risk population: Results from an international survey, the HELIOS project. Photodermatol Photoimmunol Photomed 40(6): e13014, 2024. doi: 10.1111/phpp.13014

Klinkhammer H, Staerk C, Maj C, Krawitz PM, Mayr A: Genetic Prediction Modeling in large cohort studies via boosting targeted loss functions. Stat Med 43(28):5412-5430, 2024. doi: 10.1002/sim.10249

Kuenzel NA, Dobner J, Reichert D, Rossi A, Boukamp P, Esser C: Vδ1 T cells integrated in full thickness skin equivalents: a model for the role of human skin-resident γδT cells. J Invest Dermatol S0022-202X(24)02173-0, 2024. doi: 10.1016/j.jid.2024.08.037

Dobner J, Diecke S, Krutmann J, Prigione A, Rossi A: Reassessment of marker genes in human induced pluripotent stem cells for enhanced quality control. Nat Commun 15(1):8547, 2024. doi: 10.1038/s41467-024-52922-1

Kontarakis Z, Revah O, Rossi A: CRISPR-Cas13d: RNA’s own Jedi Master in the fight against viral darkness. Mol Ther Nucleic Acids 35(4):102321, 2024. doi: 10.1016/j.omtn.2024.102321

Chen H, Chen Y, Zhou Y, Cao S, Lu J, Han L, Worzfeld T, Krutmann J, Wang J, Xia J: Optimizing skin surface metabolomics: A comprehensive evaluation of sampling methods, extraction solvents, and analytical techniques. J Invest Dermatol S0022-202X(24)02105-5, 2024. doi: 10.1016/j.jid.2024.08.027

Xia J-j, Zhong Q, Li Z-m, Wei Q-z., Jiang L-y, Duan C, Jia H-j, Tan Y-m, Han L-y, Krutmann J, Wang J, Liu X: Culture dependent and independent approaches reveal the role of specific bacteria in human skin aging. iMetaOmics e26, 2024. doi:10.1002/imo2.26

Lim HW, Passeron T, Goh CL, Kang HY, Ly F, Morita A, Ocampo-Candiani J, Puig S, Schalka S, Wei L, Demessant AL, Le Floc’h C, Kerob D, Dreno B, Krutmann J: Evaluating the frequency of mole checks by a dermatologist and correlated variables in a global survey across 17 Countries: HELIOS Project. Acta Derm Venereol 104:adv40929, 2024. doi: 10.2340/actadv.v104.40929

Wang H, Geng M, Schikowski T, Areal AT, Hu K, Li W, Coelho MSZS, Saldiva PHN, Sun W, Zhou C, Lu L, Zhao Q, Ma W: Increased risk of influenza infection during cold spells in China: National time series study. JMIR Public Health Surveill 10: e55822, 2024. doi: 10.2196/55822

Sant’Anna-Silva ACB, Botton T, Rossi A, Dobner J, Bzioueche H, Thach N, Blot L, Pagnotta S, Kleszczynski K, Steinbrink K, Mazure NM, Rocchi S, Krutmann J, Passeron T, Tulic MK: Vitiligo auto-immune response upon oxidative stress-related mitochondrial DNA release opens up new therapeutic strategies. Clin Transl Med 14(8): e1810, 2024. doi: 10.1002/ctm2.1810

Sondermann NC, Momin AA, Arold ST, Haarmann-Stemmann T: Benzotriazole UV stabilizers disrupt epidermal growth factor receptor signaling in human cells. Environ Int 190: 108886, 2024. doi: 10.1016/j.envint.2024.108886

Dreno B, Passeron T, Puig S, Lim HW, Goh CL, Kang HY, Ly F, Morita A, Ocampo-Candiani J, Schalka S, Wei L, Demessant AL, Le Floc’h C, Kerob D, Krutmann J: Are people more concerned about photoaging than skin cancer when raising awareness about risks of skin exposure? Clin Exp Dermatol 50(7): 1423-1424, 2025 (online 2024). doi: 10.1093/ced/llae225

Haarmann-Stemmann T: The aryl hydrocarbon receptor in environmentally induced cancers. Biochem Pharmacol 225:116304, 2024. doi: 10.1016/j.bcp.2024.116304

Gilaberte Y, Piquero-Casals J, Schalka S, Leone G, Brown A, Trullàs C, Jourdan E, Lim HW, Krutmann J, Passeron T: Exploring the impact of solar radiation on skin microbiome to develop improved photoprotection strategies. Photochem Photobiol 2024. doi: 10.1111/php.13962

Morita A, Lim HW, Passeron T, Goh CL, Kang HY, Ly F, Ocampo-Candiani J, Puig S, Schalka S, Wei L, Demessant AL, Le Floc’h C, Kerob D, Dreno B, Krutmann J: Attitudes and behaviors regarding sun exposure in Japan compared to Europe and North America. J Dermatol 1(7): 1004-1009, 2024. doi: 10.1111/1346-8138.17217

Passeron T, Dreno B, Puig S, Goh CL, Kang HY, Ly F, Morita A, Ocampo Candiani J, Schalka S, Wei L, Demessant-Flavigny AL, Le Floc’h C, Kerob D, Lim HW, Krutmann J: Outdoor workers and sun exposure: Results of an international survey on sun exposure behaviours and knowledge among 17 countries, the HELIOS project. J Eur Acad Dermatol Venereol, 2024. doi: 10.1111/jdv.20001

Dobner J, Nguyen T, Pavez-Giani MG, Cyganek L, Distelmaier F, Krutmann J, Prigione A, Rossi A: mtDNA Analysis using Mitopore. Mol Ther Methods Clin Dev 32(2): 101231, 2024. doi: 10.1016/j.omtm.2024.101231

Zhang R, Pu W, Zhang X, Di Y, Xu J, Zhu M, Tan Y, Liu W, Krutmann J, Wang J, Ma Y: Blue light protection factor: a method to assess the protective efficacy of cosmetics against blue light-induced skin damage in the Chinese population. Photochem Photobiol Sci 23(4): 711-718, 2024. doi: 10.1007/s43630-024-00546-1

Dobner J, Nguyen T, Dunkel A, Prigione A, Krutmann J, Rossi A: Mitochondrial DNA integrity and metabolome profile are preserved in the human induced pluripotent stem cell reference line KOLF2.1J. Stem Cell Rep 19(3): 343-350, 2024. doi: 10.1016/j.stemcr.2024.01.009

Binder S, Ramachandran H, Hildebrandt B, Dobner J, Rossi A: Prime-Editing of human ACTB in induced pluripotent stem cells to model human ACTB Loss-of-Function diseases and compensatory mechanisms. Stem Cell Res 75:103304, 2024. doi: 10.1016/j.scr.2024.103304

Granger C, Trullàs C, Sokeechand NB, Jourdan E, Krutmann J, Francois-Newton V, Hosenally M: Evaluating the factors influencing sun protection factors (SPF): Pooling data from multiple studies involving two reference ISO 24444:2019 sunscreen products (P2 and P8). Photodermatol Photoimmunol Photomed 40:e12942, 2024. doi:10.1111/phpp.12942

Vijay P, Anand A, Singh N, Schikowski T, Phuleria HC: Examining the spatial and temporal variations in the indoor gaseous, PM2.5, BC concentrations in urban homes in India. Atmos Environ 319: 120287, 2024 (online 2023). doi: 10.1016/j.atmosenv.2023.120287

Passeron T, Lim HW, Goh CL, Kang HY, Ribeyre C, Demessant-Flavigny AL, Le Floc’h C, Kerob D, Krutmann J, Comte C, Dreno B, Leccia MT: Thirty years of promoting sun safety in France: The messages are heard but not followed! J Eur Acad Dermatol Venereol 38(4): e306-e309, 2024. doi: 10.1111/jdv.19543

Passeron T, Lim HW, Goh CL, Kang HY, Ly F, Morita A, Ocampo-Candiani J, Puig S, Schalka S, Liu W, Demessant AL, Le Floc’h C, Kerob D, Dreno B, Krutmann J: Do regrets of parents about sun overexposure impact preventive measures applied on their children? J Eur Acad Dermatol Venereol 38: e199-e203, 2024. doi: 10.1111/jdv.19556

Budu-Aggrey A, …, Schikowski T, …, Paternoster L: European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation. Nat Commun 14: 6172, 2023. doi: 10.1038/s41467-023-41180-2

Krutmann J, Grether-Beck S, Makrantonaki E, Schikowski T: Hautalterungsexposom. Dermatologie 2023. doi: 10.1007/s00105-023-05210-w

Passeron T, Lim HW, Goh CL, Kang HY, Ly F, Morita A, Ocampo-Candiani J, Puig S, Schalka S, Liu W, Demessant-Flavigny AL, Le Flo’ch C, Kerob D, Dreno B, Krutmann J: Sun exposure behaviours as a compromise to paradoxical injunctions: Insight from a worldwide survey. J Eur Acad Dermatol Venereol 37: 2481-2489, 2023. doi: 10.1111/jdv.19421

Marini A, Aue N, Jaenicke T, Grether-Beck S, Trullas C, Granger C, Jourdan E, Krutmann J: Assessment of the protective effect against air pollution-induced skin pigmentation of an oral nutritional supplement containing antioxidants: A randomized, double-blinded, placebo-controlled study. J Eur Acad Dermatol Venereol 37(9): e1183-e1186, 2023. doi: 10.1111/jdv.19183

Ondrová K, Zůvalová I, Vyhlídalová B, Krasulová K, Miková E, Vrzal R, Nádvorník P, Nepal B, Kortagere S, Kopečná M, Kopečný D, Šebela M, Rastinejad F, Pu H, Soural M, Rolfes KM, Haarmann-Stemmann T, Li H, Mani S, Dvořák Z: Monoterpenoid aryl hydrocarbon receptor allosteric antagonists protect against ultraviolet skin damage in female mice. Nat Commun 14(1): 2728, 2023. doi: 10.1038/s41467-023-38478-6

Piquero-Casals J, Morgado-Carrasco D, Rozas-Muñoz E, Mir-Bonafé JF, Trullàs C, Jourdan E, Piquero-Martin J, Zouboulis CC, Krutmann J: Sun exposure, a relevant exposome factor in acne patients and how photoprotection can improve outcomes. J Cosmet Dermatol 22(6): 1919-1928, 2023. doi: 10.1111/jocd.15726

Singh N, Schikowski T: Skin diseases and emerging determinants: the need for interactive research. Br J Dermatol 188(4): 457-458, 2023. doi: 10.1093/bjd/ljad008

Granger C, Passeron T, Trullas C, Hosenally M, Sokeechand BN, Krutmann J, Lim HW: Outdoor clinical testing with reference sunscreens to determine differences in skin response between populations of different ethnicity: A combined data analysis from 128 subjects. Photodermatol Photoimmunol Photomed, 39(5): 419-427, 2023. doi: 10.1111/phpp.12871

Nojiri Y, Nakamura M, Magara T, Yamamoto A, Ikumi K, Nakamura R, Nishida E, Haarmann-Stemmann T, Morita A: Influence of aldo-keto reductase 1C3 polymorphisms in early-onset female psoriasis patients. Sci Rep 13(1): 3280, 2023. doi: 10.1038/s41598-023-30464-8

Na J, Li N, Yan L, Schikowski T, Ye R, Krutmann J, Li Z: Skin aging associated with chromium among rural housewives in northern China. Ecotoxicol Environ Saf 253: 114676, 2023. doi: 10.1016/j.ecoenv.2023.114676

Clahsen T, Hadrian K, Notara M, Schlereth SL, Howaldt A, Prokosch V, Volatier T, Hos D, Schroedl F, Kaser-Eichberger A, Heindl LM, Steven P, Bosch JJ, Steinkasserer A, Rokohl AC, Liu H, Mestanoglu M, Kashkar H, Schumacher B, Kiefer F, Schulte-Merker S, Matthaei M, Hou Y, Fassbender S, Jantsch J, Zhang W, Enders P, Bachmann B, Bock F, Cursiefen C: The novel role of lymphatic vessels in the pathogenesis of ocular diseases. Prog Retin Eye Res 96: 101157, 2023. doi: 10.1016/j.preteyeres.2022.101157

Cai C, Zeng B, Lin L, Zheng M, Burki C, Grether-Beck S, Krutmann J: An oral French maritime pine bark extract improves hair density in menopausal women: A randomized, placebo-controlled, double blind intervention study. Health Sci Rep 6(1): e1045, 2023. doi: 10.1002/hsr2.1045

Peng Q, Liu Y, Huels A, Zhang C, Yu Y, Qiu W, Cai X, Zhao Y, Schikowski T, Merches K, Liu Y, Yang Y, Wang J, Zhao Y, Jin L, Zhang L, Krutmann J, Wang S: Genetic variants in Telomerase Reverse Transcriptase contribute to solar lentigines. J Invest Dermatol 143(6): 1062-1072, 2023 (online 2022). doi: 10.1016/j.jid.2022.11.016 (*equal contribution)

Vogeley C, Kress S, Lang D, Vogel CFA, Hartung F, Brenden H, Nakamura M, Grether-Beck S, Rossi A, Krutmann J, Schikowski T, Haarmann-Stemmann T: A gene variant of AKR1C3 contributes to interindividual susceptibilities to atopic dermatitis triggered by particulate air pollution. Allergy 78(5): 1372-1375, 2023 (online 2022). doi: 10.1111/all.15622 (*equal contribution)

Sondermann NC, Faßbender S, Hartung F, Hätälä AM, Rolfes KM, Vogel CFA, Haarmann-Stemmann T: Functions of the aryl hydrocarbon receptor (AHR) beyond the canonical AHR/ARNT signaling pathway. Biochem Pharmacol 208: 115371, 2023 (online 2022). doi: 10.1016/j.bcp.2022.115371

Wigmann C, Hüls A, Krutmann J, Schikowski T: Estimating the relative contribution of environmental and genetic risk factors to different aging traits by combining correlated variables into weighted risk scores. Int J Environ Res Public Health 19(24): 16746, 2022. doi: 10.3390/ijerph192416746

Liu W, Krutmann J, Tian Y, Granger C, Piquero-Casals J, Trullàs C, Passeron T, Lim HW, Lai W: Commentary: Facial aesthetic dermatological procedures and photoprotection in Chinese populations. Dermatol Ther (Heidelb) 13(1): 13-27, 2023 (online 2022). doi: 10.1007/s13555-022-00862-3

Sies H: Oxidativer Stress, Eustress und Distress: H₂O₂ als Signalmolekül. Biospektrum 28: 685–690, 2022. doi: 10.1007/s12268-022-1862-y

Krutmann J, Piquero-Casals J, Morgado-Carrasco D, Granger C, Trullàs C, Passeron T, Lim HW: Photoprotection for people with skin of colour: needs and strategies. Br J Dermatol 188(2): 168-175, 2023 (online 2022). doi: 10.1093/bjd/ljac046

Chen H, Zhao Q, Zhong Q, Duan C, Krutmann J, Wang, J, Xia J: Skin microbiome, metabolome and skin phenome, from the perspectives of skin as an ecosystem. Phenomics 2: 363–382, 2022. doi: 10.1007/s43657-022-00073-y

Granger C, Petkar G, Hosenally M, Bustos J, Trullàs C, Passeron T, Krutmann J: Evaluation of a sunscreen product compared with reference standards P3, P5 and P8 in outdoor conditions: A randomized, double-blinded, intra-individual study in healthy subjects. Dermatol Ther (Heidelb) 12(11): 2531-2546, 2022. doi: 10.1007/s13555-022-00815-w

Hiebert P, Martyts A, Schwestermann J, Janke K, Hafner J, Boukamp P, Mazza E, Werner S: Activation of Nrf2 in fibroblasts promotes a skin aging phenotype via an Nrf2-miRNA-collagen axis. Matrix Biol 113: 39-60, 2022. doi: 10.1016/j.matbio.2022.09.002

Krutmann J: Environmental Dermatitis. Dermatitis 33(5): 305. 2022. doi: 10.1097/DER.0000000000000944

von Mikecz A: Exposome, molecular pathways and one health: The invertebrate Caenorhabditis elegans. Int J Mol Sci 23(16): 9084, 2022. doi: 10.3390/ijms23169084

Dobner J, Ramachandran H, Rossi A: Genome editing in translational medicine: An inventory. Front Biosci (Landmark Ed) 27(8): 241, 2022. doi: 10.31083/j.fbl2708241

Vogeley C, Nguyen T, Woeste S, Krutmann J, Haarmann-Stemmann T, Rossi A: Rapid and simple analysis of short and long sequencing reads using Duesselpore^TM. Front Genet 13: 931996, 2022. doi: 10.3389/fgene.2022.931996

Wei Q, Li Z, Gu Z, Liu X, Krutmann J, Wang J, Xia J: Shotgun metagenomic sequencing reveals skin microbial variability from different facial sites. Front Microbiol 13: 933189, 2022. doi: 10.3389/fmicb.2022.933189

Plitta-Michalak B, Stricker N, Pavez Loriè E, Chen I, Pollet M, Krutmann J, Volkmer B, Greinert R, Boukamp P, Rapp A: Development and characterisation of an irradiation device for biomedical studies covering the solar spectrum with individual regulated spectral bands. Photochem Photobiol Sci 21(9): 1701-1717, 2022. doi: 10.1007/s43630-022-00252-w

Duteil L, Queille-Roussel C, Aladren S, Bustos X, Trullas C, Granger C, Krutmann J, Passeron T: Prevention of polymorphic light eruption afforded by a very high broad-spectrum protection sunscreen containing Ectoin. Dermatol Ther (Heidelb) 12(7): 1603-1613, 2022. doi: 10.1007/s13555-022-00755-5

Nguyen T, Ramachandran H, Martins S, Krutmann J, Rossi A: Identification of genome edited cells using CRISPRnano. Nucleic Acids Res 50(W1): W199–203, 2022. doi: 10.1093/nar/gkac440

Yusuf N, Haarmann-Stemmann T, Nakamura M: Editorial: Environment and skin cancer. Front Oncol 12: 924225, 2022. doi: 10.3389/fonc.2022.924225

Surber C, Krutmann J: Sonnenschutz: Wichtiger denn je! [Sun protection measures: more important than ever!]. Hautarzt 73(4): 249-250, 2022. doi: 10.1007/s00105-022-04964-z

Wolf P, Krutmann J: Sonnenschutz der Zukunft: Herausforderungen und Möglichkeiten [Sunscreens of the future: challenges and opportunities]. Hautarzt 73(4): 257-265, 2022. doi: 10.1007/s00105-022-04959-w

Rossi A, Lickfett S, Martins S, Prigione A: A call for consensus guidelines on monitoring the integrity of nuclear and mitochondrial genomes in human pluripotent stem cells. Stem Cell Rep 17(4): 707-710, 2022. doi: 10.1016/j.stemcr.2022.01.019

Vogeley C, Rolfes KM, Krutmann J, Haarmann-Stemmann T: The aryl hydrocarbon receptor in the pathogenesis of environmentally-induced squamous cell carcinomas of the skin. Front Oncol 12: 841721, 2022. doi: 10.3389/fonc.2022.841721

Sies H, Belousov VV, Chandel NS, Davies MJ, Jones DP, Mann GE, Murphy MP, Yamamoto M, Winterbourn C: Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology. Nat Rev Mol Cell Biol 23(7): 499-515, 2022. doi: 10.1038/s41580-022-00456-z

von Mikecz A, Scharf A: Pollution – bring the field into the lab. Nature 602(7897): 386, 2022. doi: 10.1038/d41586-022-00444-5

Liu W, Jie L, Liu D, Makino ET, Krutmann J, Mehta RC: Protective effects of a day/night dual-antioxidant serum on skin: A randomized, regimen-controlled study in Chinese women exposed to air pollution. J Cosmet Dermatol 22(1): 245-254, 2023. doi: 10.1111/jocd.14839

Neves JR, Grether-Beck S, Krutmann J, Correia P, Gonçalves JE Jr, Sant’Anna B, Kerob D: Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs. J Cosmet Dermatol 21(10): 4462-4469, 2022. doi: 10.1111/jocd.14837

Ishihara Y, Kado SY, Bein KJ, He Y, Pouraryan AA, Urban A, Haarmann-Stemmann T, Sweeney C and Vogel CFA: Aryl hydrocarbon receptor signaling synergizes with TLR/NF-κB-signaling for induction of IL-22 through canonical and non-canonical AhR pathways. Front Toxicol 3: 787360, 2022. doi: 10.3389/ftox.2021.787360

Tham M, Stark H-J, Jauch A, Harwood C, Pavez Lorie E, Boukamp P: Adverse effects of Vemurafenib on skin integrity: Hyperkeratosis and skin cancer initiation due to altered MEK/ERK-signaling and MMP activity. Front Oncol 12: 827985, 2022. doi: 10.3389/fonc.2022.827985

Fehsel K, Schwanke K, Kappel BA, Fahimi E, Meisenzahl-Lechner E, Esser C, Hemmrich K, Haarmann-Stemmann T, Kojda G, Lange-Asschenfeldt C: Activation of the aryl hydrocarbon receptor by clozapine induces preadipocyte differentiation and contributes to endothelial dysfunction. J Psychopharmacol 36(2): 191-201, 2022. doi: 10.1177/02698811211055811

Li B, Cheng Y, Tan Y, Wang F, Hu W, Wang X, Liu W, Krutmann J, Wang S, Zou Y: Analysis of factors influencing skin reactions to sunscreens, skin whitening products, and deodorants: Results from a large-scale patch test dataset in China. J Cosmet Dermatol 21(9): 3986-3992, 2022 (online 2021). doi: 10.1111/jocd.14699

Rossi A, Kontarakis Z: Beyond Mendelian inheritance: genetic buffering and phenotype variability. Phenomics 2: 79-87, 2022 (online 2021). doi: 10.1007/s43657-021-00030-1

Vogeley C, Sondermann NC, Woeste S, Momin AA, Gilardino V, Hartung F, Heinen M, Maaß SK, Mescher M, Pollet M, Rolfes KM, Vogel CFA, Rossi A, Lang D, Arold ST, Nakamura M, Haarmann-Stemmann T: Unraveling the differential impact of PAHs and dioxin-like compounds on AKR1C3 reveals the EGFR extracellular domain as a critical determinant of the AHR response. Environ Int 158: 106989, 2022 (online 2021). doi: 10.1016/j.envint.2021.106989

Piquero-Casals J, Morgado-Carrasco D, Granger C, Trullàs C, Jesús-Silva A, Krutmann J: Urea in dermatology. A review of its emollient, moisturizing, keratolytic, skin barrier enhancing and antimicrobial properties. Dermatol Ther (Heidelb) 11(6): 1905-1915, 2021. doi: 10.1007/s13555-021-00611-y

Faßbender S, Sondenheimer K, Majora M, Schindler J, Opitz FV, Pollet M, Haarmann-Stemmann T, Krutmann J, Weighardt H: Keratinocytes counteract UVB-induced immunosuppression in mice via HIF1a signaling. J Invest Dermatol 142(4):1183-1193, 2022 (online 2021). doi: 10.1016/j.jid.2021.07.185

Rolfes KM, Sondermann NC, Vogeley C, Dairou J, Gilardino V, Wirth R, Meller S, Homey B, Krutmann J, Lang D, Nakamura M, Haarmann-Stemmann T: Inhibition of 6-formylindolo[3,2-b]carbazole metabolism sensitizes keratinocytes to UVA-induced apoptosis: Implications for vemurafenib-induced phototoxicity. Redox Biol 46: 102110, 2021. doi: 10.1016/j.redox.2021.102110

Grether-Beck S, Marini A, Jaenicke T, Brenden H, Felsner I, Aue N, Brynjolfsdottir A, Krutmann J: Blue Lagoon Algae improve uneven skin pigmentation: Results from in vitro studies and from a monocentric, randomized, double-blind, vehicle-controlled, split-face study. Skin Pharmacol Physiol 35(2): 77-86, 2022 (online 2021). doi: 10.1159/000518781

Breuckmann P, Meinke MC, Jaenicke T, Krutmann J, Rasulev U, Keck CM, Müller RH, Klein AL, Lademann J, Patzelt A: Influence of nanocrystal size on the in vivo absorption kinetics of caffeine after topical application. Eur J Pharm Biopharm 167: 57-64, 2021. doi: 10.1016/j.ejpb.2021.07.006

Li B, Cheng Y, Tan Y, Wang F, Hu W, Wang X, Liu W, Krutmann J, Wang S, Zou Y: Analysis of factors influencing patch test reactions: Results from a large- population-based study in Chinese. J Cosmet Dermatol 21(5): 2183-2188, 2022 (online 2021). doi: 10.1111/jocd.14338

Martins S, Hacheney I, Teichweyde N, Hildebrandt B, Krutmann J, Rossi A: Generation of an induced pluripotent stem cell line (IUFi001) from a Cockayne syndrome patient carrying a mutation in the ERCC6 gene. Stem Cell Res 55: 102456, 2021. doi: 10.1016/j.scr.2021.102456

Sies H, Ursini F: Homeostatic control of redox status and health. IUBMB Life 74(1): 24-28, 2022 (online 2021). doi: 10.1002/iub.2519

Passeron T, Zouboulis CC, Tan J, Andersen ML, Katta R, Lyu X, Aguilar L, Kerob D, Morita A, Krutmann J, Peters EMJ: Adult skin acute stress responses to short-term environmental and internal aggression from exposome factors. J Eur Acad Dermatol Venereol 35(10): 1963-1975, 2021. doi: 10.1111/jdv.17432

Granger C, Ong G, Andres P, Trullàs C, Hosenally M, Lai W, Liu W, Krutmann J, Passeron T, Lim HW: Outdoor sunscreen testing with high-intensity solar exposure in a Chinese and Caucasian population. Photodermatol Photoimmunol Photomed 38(1): 19-28, 2022 (online 2021). doi: 10.1111/phpp.12710

Krutmann J, Granger C, Trullàs C, Passeron T: Daily photoprotection: What does it really mean? Photodermatol Photoimmunol Photomed 37(6): 569-570, 2021. doi: 10.1111/phpp.12707

van den Bogaard EH, Esser C, Perdew G: The aryl hydrocarbon receptor at the forefront of host-microbe interactions in the skin: a perspective on current knowledge gaps and directions for future research and therapeutic applications. Exp Dermatol 30(10): 1477-1483, 2021. doi: 10.1111/exd.14409

Lim H, Kohli I, Granger C, Trullas C, Piquero-Casals J, Narda M, Masson P, Krutmann J, Passeron T: Photoprotection of the skin from visible light-induced pigmentation: Current testing methods and proposed harmonization. J Invest Dermatol 141(11): 2569-2576, 2021. doi: 10.1016/j.jid.2021.03.012

Grether-Beck S, Felsner I, Brenden H, Marini A, Jaenicke T, Aue N, Welss T, Uthe I, Krutmann J: Air pollution-induced tanning of human skin. Br J Dermatol 185(5): 1026-1034, 2021. doi: 10.1111/bjd.20483

Budden T, Gaudy-Marqueste C, Porter A, Kay E, Gurung S, Earnshaw CH, Roeck K, Craig S, Traves V, Krutmann J, Muller P, Motta L, Zanivan S, Malliri A, Furney SJ, Nagore E, Virós A: Ultraviolet light-induced collagen degradation inhibits melanoma invasion. Nat Commun 12(1): 2742, 2021. doi: 10.1038/s41467-021-22953-z

Tigges J, Bielec K, Brockerhoff G, Hildebrandt B, Hübenthal U, Kapr J, Koch K, Teichweyde N, Wieczorek D, Rossi A, Fritsche E: Academic application of Good Cell Culture Practice for induced pluripotent stem cells. ALTEX 38(4): 595-614, 2021. doi: 10.14573/altex.2101221

Baswan SM, Klosner AE, Weir C, Salter-Venzon D, Gellenbeck KW, Leveret J, Krutmann J: Role of ingestible carotenoids in skin protection: A review of clinical evidence. Photodermatol Photoimmunol Photomed 37(6): 490-504, 2021. doi: 10.1111/phpp.12690

Luger T, Amagai M, Dreno B, Dagnelie MA, Liao W, Kabashima K, Schikowski T, Proksch E, Elias PM, Simon M, Simpson E, Grinich E, Schmuth M: Atopic dermatitis: Role of the skin barrier, environment, microbiome, and therapeutic agents. J Dermatol Sci 102(3): 142-157, 2021. doi: 10.1016/j.jdermsci.2021.04.007

Ramachandran H, Martins S, Kontarakis Z, Krutmann J, Rossi A: Fast but not furious: a streamlined selection method for genome edited cells. Life Sci Alliance 4(6): e202101051, 2021. doi: 10.26508/lsa.202101051

Krutmann J, Schalka S, Watson REB, Liu W, Morita A: Daily photoprotection to prevent photoaging. Photodermatol Photoimmunol Photomed 37(6): 482-489, 2021. doi: 10.1111/phpp.12688

Correia Carreira S, Taghavi M, Pavez Loriè E, Rossiter J: FleXert: A soft, actuatable multiwell plate insert for cell culture under stretch. ACS Biomater Sci Eng 7(6): 2225-2245, 2021. doi: 10.1021/acsbiomaterials.0c01448

Zhao H, Wu J, Wang N, Grether-Beck S, Krutmann J, Wei L: Oral Pycnogenol® intake benefits the skin in urban Chinese outdoor workers: A randomized, placebo-controlled, double blind, and crossover intervention study. Skin Pharmacol Physiol 34: 135-145, 2021. doi: 10.1159/000514323

Passeron T, Lim HW, Goh CL, Kang HY, Ly F, Morita A, Ocampo Candiani J, Puig S, Schalka S, Wei L, Dréno B, Krutmann J: Photoprotection according to skin phototype and dermatoses: Practical recommendations from an expert panel. J Eur Acad Dermatol Venereol 35(7): 1460-1469, 2021. doi: 10.1111/jdv.17242

Vogel CFA, Lazennec G, Kado SY, Dahlem C, He Y, Castaneda A, Ishihara Y, Vogeley C, Rossi A, Haarmann-Stemmann T, Jugan J, Mori H, Borowsky AD, La Merrill MA, Sweeney C: Targeting the aryl hydrocarbon receptor signaling pathway in breast cancer development. Front Immunol 12: 625346, 2021. doi: 10.3389/fimmu.2021.625346

Haarmann-Stemmann T, Sutter TR, Krutmann J, Esser C: The mode of action of tapinarof may not only depend on the activation of cutaneous aryl hydrocarbon receptor signaling but also on its antimicrobial activity. J Am Acad Dermatol 85(1): e33-e34, 2021. doi: 10.1016/j.jaad.2021.01.103

Coppari S, Colomba M, Fraternale D, Brinkmann V, Romeo M, Rocchi MBL, Di Giacomo B, Mari M, Guidi L, Ramakrishna S, Ventura N, Albertini MC: Antioxidant and anti-inflammaging ability of prune (Prunus Spinosa L.) extract result in improved wound healing efficacy. Antioxidants (Basel) 10(3): 374, 2021. doi: 10.3390/antiox10030374

Li Z, Xia J, Jiang L, Tan Y, An Y, Zhu X, Ruan J, Chen Z, Zhen H, Ma Y, Jie Z, Xiao L, Yang H, Wang J, Kristiansen K, Xu X, Jin L, Nie C, Krutmann J, Liu X, Wang J: Characterization of the human skin resistome and identification of two microbiota cutotypes. Microbiome* 9(1): 47, 2021. doi: 10.1186/s40168-020-00995-7 (*equal contribution)

Esser C: Trajectory shifts in interdisciplinary research of the aryl hydrocarbon receptor – a personal perspective on thymus and skin. Int J Mol Sci 22(4): 1844, 2021. doi: 10.3390/ijms22041844

Krutmann J, Schikowski T, Morita A, Berneburg M: Environmentally-induced (extrinsic) skin aging: Exposomal factors and underlying mechanisms. J Invest Dermatol 141(4S): 1096-1103, 2021. doi: 10.1016/j.jid.2020.12.011

Sies H: Oxidative eustress: On constant alert for redox homeostasis. Redox Biol 41: 101867, 2021. doi: 10.1016/j.redox.2021.101867

Neale RE, Barnes PW, Robson TM, Neale PJ, Williamson CE, Zepp RG, Wilson SR, Madronich S, Andrady AL, Heikkilä AM, Bernhard GH, Bais AF, Aucamp PJ, Banaszak AT, Bornman JF, Bruckman LS, Byrne SN, Foereid B, Häder DP, Hollestein LM, Hou WC, Hylander S, Jansen MAK, Klekociuk AR, Liley JB, Longstreth J, Lucas RM, Martinez-Abaigar J, McNeill K, Olsen CM, Pandey KK, Rhodes LE, Robinson SA, Rose KC, Schikowski T, Solomon KR, Sulzberger B, Ukpebor JE, Wang QW, Wängberg SÅ, White CC, Yazar S, Young AR, Young PJ, Zhu L, Zhu M: Environmental effects of stratospheric ozone depletion, UV radiation, and interactions with climate change: UNEP Environmental Effects Assessment Panel, update 2020. Photochem Photobiol Sci 20(1): 1-67, 2021. doi: 10.1007/s43630-020-00001-x

Krutmann J, Berneburg M: Photodermatologie. Hautarzt 72(1): 1, 2021. doi: 10.1007/s00105-020-04746-5

Krutmann J, Berneburg M: Lichtalterung (Photoaging) der Haut: Was gibt es Neues? Hautarzt 72(1): 2-5, 2021 (online 2020). doi: 10.1007/s00105-020-04747-4

Gappa M, Filipiak-Pittroff B, Libuda L, von Berg A, Koletzko S, Bauer CP, Heinrich J, Schikowski T, Berdel D, Standl M: Long-term effects of hydrolyzed formulae on atopic diseases in the GINI study. Allergy 76(6): 1903-1907, 2021 (online 2020). doi: 10.1111/all.14709

Mekić S, Wigmann C, Gunn DA, Kayser M, Jacobs LC, Schikowski T, Nijsten T, Pardo LM: Genetics of facial telangiectasia in the Rotterdam study; a genome-wide association study and candidate gene approach. J Eur Acad Dermatol Venereol 35(3): 749-754, 2021 (online 2020). doi: 10.1111/jdv.17014

Esser C, Boots AM, Caignard A, Ciraci C, Grčević D, Knapp S, Montoya M, Di Rosa F, Saksida T, Stravinskiene D, Deniz G: The impact of COVID-19 lock-downs for European (female) immunologists – our views as members of the EFIS gender and diversity task force. Euro J Immunol 50(12): 1855-1862, 2020. doi: 10.1002/eji.202070125

Ghashghaei O, Pedrola M, Seghetti F, Martin VV, Zavarce R, Babiak M, Novacek J, Hartung F, Rolfes KM, Haarmann-Stemmann T, Lavilla R: Extended multicomponent reactions with indole aldehydes: Access to unprecedented polyheterocyclic scaffolds, ligands of the aryl hydrocarbon receptor. Angew Chem Int Edit 60(5): 2603-2608, 2021 (online 2020). doi: 10.1002/anie.202011253

Alkotob SS, Cannedy C, Harter K, Movassagh H, Paudel B, Prunicki M, Sampath V, Schikowski T, Smith E, Zhao Q, Traidl-Hoffmann C, Nadeau KC: Advances and novel developments in environmental influences on the development of atopic diseases. Allergy 75(12): 3077-3086, 2020. doi: 10.1111/all.14624

Sies H: Findings in redox biology: from H₂O₂ to oxidative stress. J Biol Chem 295(39): 13458-13473, 2020. doi: 10.1074/jbc.X120.015651

Pavez-Lorie E, Stricker N, Plitta-Michalak B, Peng-Chen I, Volkmer B, Greinert R, Jauch A, Boukamp P, Rapp A: Characterisation of the novel spontaneously immortalized and invasively growing human skin keratinocyte line HaSKpw. Sci Rep 10(1): 15196, 2020. doi: 10.1038/s41598-020-71315-0

Sies H: Oxidative stress: Concept and some practical aspects. Antioxidants 9(9): 852, 2020. doi: 10.3390/antiox9090852

Passeron T, Krutmann J, Andersen ML, Katta R, Zouboulis CC: Clinical and biological impact of the exposome on the skin. J Eur Acad Dermatol Venereol 34 (Suppl 4): 4-25, 2020. doi: 10.1111/jdv.16614

Esser C, Hochrath K, Schikowski T, Haarmann-Stemmann T: COVID-19 research: toxicological input urgently needed! Arch Toxicol 94(7): 2547-2548, 2020. doi: 10.1007/s00204-020-02803-5

Sies H: Schrödingers Koffer. BIOspektrum 26: 345-346, 2020. doi: 10.1007/s12268-020-1364-8

Bernhard GH, Neale RE, Barnes PW, Neale PJ, Zepp RG, Wilson SR, Andrady AL, Bais AF, McKenzie RL, Aucamp PJ, Young PJ, Liley JB, Lucas RM, Yazar S, Rhodes LE, Byrne SN, Hollestein LM, Olsen CM, Young AR, Robson TM, Bornman JF, Jansen MAK, Robinson SA, Ballaré CL, Williamson CE, Rose KC, Banaszak AT, Häder DP, Hylander S, Wängberg SÅ, Austin AT, Hou WC, Paul ND, Madronich S, Sulzberger B, Solomon KR, Li H, Schikowski T, Longstreth J, Pandey KK, Heikkilä AM, White CC: Environmental effects of stratospheric ozone depletion, UV radiation and interactions with climate change: UNEP Environmental Effects Assessment Panel, update 2019. Photochem Photobiol Sci 19(5): 542-584, 2020. doi: 10.1039/d0pp90011g

Sies H, Jones DP: Reactive oxygen species (ROS) as pleiotropic physiological signalling agents. Nat Rev Mol Cell Biol 21(7): 363-383, 2020. doi: 10.1038/s41580-020-0230-3

Merches K, Schiavi A, Weighardt H, Steinwachs S, Teichweyde N, Förster I, Hochrath K, Schumak B, Ventura N, Petzsch P, Köhrer K, Esser C: AHR signaling dampens inflammatory signature in neonatal skin γδ T cells. Int J Mol Sci 21(6): 2249, 2020. doi: 10.3390/ijms21062249

Häselbarth L, Ouwens DM, Teichweyde N, Hochrath K, Merches K, Esser C: The small chain fatty acid butyrate antagonizes the TCR-stimulation-induced metabolic shift in murine epidermal gamma delta T cells. EXCLI J 19: 334-350, 2020. doi: 10.17179/excli2020-1123

Madhusudhan N, Pausan MR, Halwachs B, Durdević M, Windisch M, Kehrmann J, Patra V, Wolf P, Boukamp P, Moissl-Eichinger C, Cerroni L, Becker JC, Gorkiewicz G: Molecular profiling of keratinocyte skin tumors links Staphylococcus aureus overabundance and increased human β-Defensin-2 expression to growth promotion of squamous cell carcinoma. Cancers (Basel) 12(3): 541, 2020. doi: 10.3390/cancers12030541

Pavez Loriè E, Boukamp P: Methods in cell biology: Cell-derived matrices. Methods Cell Biol 156: 309-332, 2020. doi: 10.1016/bs.mcb.2019.11.012

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