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2024
Dobner J
, Diecke S,
Krutmann J
, Prigione A,
Rossi A
:
Reassessment of marker genes in human induced pluripotent stem cells for enhanced quality control
.
Nat Commun
15(1):8547, 2024. doi: 10.1038/s41467-024-52922-1
Lim HW, Passeron T, Goh CL, Kang HY, Ly F, Morita A, Ocampo-Candiani J, Puig S, Schalka S, Wei L, Demessant AL, Le Floc’h C, Kerob D, Dreno B,
Krutmann J
:
Evaluating the frequency of mole checks by a dermatologist and correlated variables in a global survey across 17 Countries: HELIOS Project.
Acta Derm Venereol
104:adv40929, 2024. doi: 10.2340/actadv.v104.40929
Kapr J
,
Scharkin I
,
Ramachandran H
, Westhoff P,
Pollet M
,
Dangeleit S
,
Brockerhoff G
,
Rossi A
,
Koch K
,
Krutmann J
,
Fritsche E
:
HiPSC-derived 3D neural models reveal neurodevelopmental pathomechanisms of the Cockayne Syndrome B
.
Cell Mol Life Sci
81(1):368, 2024. doi: 10.1007/s00018-024-05406-w
Sant’Anna-Silva ACB, Botton T,
Rossi A
,
Dobner J
, Bzioueche H,
Thach N
, Blot L, Pagnotta S, Kleszczynski K, Steinbrink K, Mazure NM, Rocchi S,
Krutmann J
, Passeron T, Tulic MK:
Vitiligo auto-immune response upon oxidative stress-related mitochondrial DNA release opens up new therapeutic strategies
.
Clin Transl Med
14(8): e1810, 2024. doi: 10.1002/ctm2.1810
Sondermann NS
, Momin AA, Arold ST,
Haarmann-Stemmann T
:
Benzotriazole UV stabilizers disrupt epidermal growth factor receptor signaling in human cells.
Environ Int
190: 108886, 2024. doi: 10.1016/j.envint.2024.108886
Zhao Z, Chu J, Ren J, Xu C, Xu X, Cao Y,
Schikowski T
,
Zhao Q
, Liu Q, Chen G, Lu Z, Guo X, Ma W, Wang H, Ma J:
Effect modification of heat-related mortality risk by air pollutants in Shandong, China
.
Am J Trop Med Hyg
111(2):440-446, 2024. doi: 10.4269/ajtmh.23-0295
Madronich S, Bernhard GH, Neale PJ, Heikkilä A, Andersen MPS, Andrady AL, Aucamp PJ, Bais AF, Banaszak AT, Barnes PJ, Bornman JF, Bruckman LS, Busquets R, Chiodo G, Häder DP, Hanson ML, Hylander S, Jansen MAK, Lingham G, Lucas RM, Calderon RM, Olsen C, Ossola R, Pandey KK, Petropavlovskikh I, Revell LE, Rhodes LE, Robinson SA, Robson TM, Rose KC,
Schikowski T
, Solomon KR, Sulzberger B, Wallington TJ, Wang QW, Wängberg SÅ, White CC, Wilson SR, Zhu L, Neale RE:
Continuing benefits of the Montreal Protocol and protection of the stratospheric ozone layer for human health and the environment
.
Photochem Photobiol Sci
23(6): 1087-1115, 2024. doi: 10.1007/s43630-024-00577-8
Piragine E, De Felice M, Germelli L, Brinkmann V, Flori L, Martini C, Calderone V,
Ventura N
, Da Pozzo E, Testai L:
The Citrus flavanone naringenin prolongs the lifespan in C. elegans and slows signs of brain aging in mice
.
Exp Gerontol
194:112495, 2024. doi: 10.1016/j.exger.2024.112495
Mikolajczyk R, Diexer S, Klee B, Pfrommer L, Purschke O, Fricke J, Ahnert P, Gabrysch S, Gottschick C, Bohn B, Brenner H, Buck C, Castell S, Gastell S, Greiser KH, Harth V, Heise JK, Holleczek B, Kaaks R, Keil T, Krist L, Leitzmann M, Lieb W, Meinke-Franze C, Michels KB, Velásquez IM, Obi N, Panreck L, Peters A, Pischon T,
Schikowski T
, Schmidt B, Standl M, Stang A, Völzke H, Weber A, Zeeb H, Karch A:
Likelihood of post-COVID condition in people with hybrid immunity; data from the German National Cohort (NAKO)
.
J Infect
89(2): 106206, 2024. doi: 10.1016/j.jinf.2024.106206
Kress S
, Lane TJ, Brown D, Smith CL, Gao CX, McCrabb T, Thomas M, Borg BM, Thompson BR, Abramson MJ:
Association between PM
2.5
from a coal mine fire and FeNO concentration 7.5 years later
.
BMC Pulm Med
24(1): 272, 2024. doi: 10.1186/s12890-024-03075-w
Mayer M, Cengiz-Dartenne SC, Thiem M, Hatzfeld P, Semeniuk A, Wang N, Strugnell RA, Förster I,
Weighardt H
:
Dysregulation of stress erythropoiesis and enhanced susceptibility to Salmonella Typhimurium infection in AhR-deficient mice
.
J Infect Dis
, 2024. doi: 10.1093/infdis/jiae304
Dreno B, Passeron T, Puig S, Lim HW, Goh CL, Kang HY, Ly F, Morita A, Ocampo-Candiani J, Schalka S, Wei L, Demessant AL, Le Floc’h C, Kerob D,
Krutmann J
:
Are people more concerned about photoaging than skin cancer when raising awareness about risks of skin exposure?
Clin Exp Dermatol
, 2024. doi: 10.1093/ced/llae225
Graelmann FJ, Gondorf F, Majlesain Y, Niemann B, Klepac K, Gosejacob D, Gottschalk M, Mayer M, Iriady I, Hatzfeld P, Lindenberg SK, Wunderling K, Thiele C, Abdullah Z, He W, Hiller K, Händler K, Beyer MD, Ulas T, Pfeifer A,
Esser C
,
Weighardt H
, Förster I, Reverte-Salisa L:
Differential cell type-specific function of the aryl hydrocarbon receptor and its repressor in diet-induced obesity and fibrosis.
Mol Metab
85: 101963, 2024. doi: 10.1016/j.molmet.2024.101963
Agostini F, Pereyra L, Dale J, Yambire KF,
Maglioni S
,
Schiavi A
,
Ventura N
, Milosevic I, Raimundo N:
Upregulation of cholesterol synthesis by lysosomal defects requires a functional mitochondrial respiratory chain
.
J Biol Chem
300(7): 107403, 2024. doi: 10.1016/j.jbc.2024.107403
Dugershaw-Kurzer B, Bossart J, Buljan M, Hannig Y, Zehnder S, Gupta G, Kissling VM, Nowak-Sliwinska P, van Beijnum JR, Griffioen AW,
Masjosthusmann S
,
Zühr E
,
Fritsche E
, Hornung R, Rduch T, Buerki-Thurnherr T:
Nanoparticles dysregulate the human placental secretome with consequences on angiogenesis and vascularization
.
Adv Sci (Weinh)
20: e2401060, 2024. doi: 10.1002/advs.202401060
Haarmann-Stemmann T
:
The aryl hydrocarbon receptor in environmentally induced cancers
.
Biochem Pharmacol
225:116304, 2024. doi: 10.1016/j.bcp.2024.116304
Hara A, Sato T,
Kress S
, Suzuki K, Pham KO, Tajima A,
Schikowski T
, Nakamura H:
Sex-specific associations between air pollutants and asthma prevalence in Japanese adults: a population-based study
.
Int J Environ Health Res
, 2024. doi: 10.1080/09603123.2024.2352597
Gilaberte Y, Piquero-Casals J, Schalka S, Leone G, Brown A, Trullàs C, Jourdan E, Lim HW,
Krutmann J
, Passeron T:
Exploring the impact of solar radiation on skin microbiome to develop improved photoprotection strategies.
Photochem Photobiol
2024. doi: 10.1111/php.13962
Morita A, Lim HW, Passeron T, Goh CL, Kang HY, Ly F, Ocampo-Candiani J, Puig S, Schalka S, Wei L, Demessant AL, Le Floc’h C, Kerob D, Dreno B,
Krutmann J
:
Attitudes and behaviors regarding sun exposure in Japan compared to Europe and North America
.
J Dermatol
1(7): 1004-1009, 2024. doi: 10.1111/1346-8138.17217
Sies H
, Mailloux RJ, Jakob U:
Fundamentals of redox regulation in biology
.
Nat Rev Mol Cell Biol,
2024. doi: 10.1038/s41580-024-00730-2
Fehsel K, Bouvier M-L, Capobianco L, Lunetti P, Klein B, Oldiges M,
Majora M
, Löffler S:
Neuroreceptor inhibition by Clozapine triggers mitohormesis and metabolic reprogramming in human blood cells
.
Cells
13(9): 762, 2024. doi: 10.3390/cells13090762
Tal T, Myhre O,
Fritsche E
, Rüegg J, Craenen K, Aiello-Holden K, Agrillo C, Babin PJ, Escher BI, Dirven H, Hellsten K, Dolva K, Hessel E, Heusinkveld HJ, Hadzhiev Y, Hurem S, Jagiello K, Judzinska B, Klüver N, Knoll-Gellida A, Kühne BA, Leist M, Lislien M, Lyche JL, Müller F, Colbourne JK, Neuhaus W, Pallocca G, Seeger B,
Scharkin I
, Scholz S, Spjuth O, Torres-Ruiz M,
Bartmann K
:
New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project
.
Front Toxicol
6: 1359507, 2024. doi: 10.3389/ftox.2024.1359507
Singh N
,
Areal AT
, Breitner S, Zhang S, Agewall S,
Schikowski T
, Schneider A:
Heat and cardiovascular mortality: An epidemiological perspective
.
Circ Res
134(9): 1098-1112, 2024. doi: 10.1161/CIRCRESAHA.123.323615
Bredeck G
, Dos S Souza EJ,
Wigmann C
, Fomba KW, Herrmann H,
Schins RPF:
The influence of long-range transported Saharan dust on the inflammatory potency of ambient PM
2.5
and PM
10
.
Environ Res
252(3): 119008, 2024. doi: 10.1016/j.envres.2024.119008
Loerch C,
Szepanowski LP
, Reiss J, Adjaye J and Graffmann N:
Forskolin induces FXR expression and enhances maturation of iPSC-derived hepatocyte-like cells
.
Front Cell Dev Biol
12: 1383928, 2024. doi: 10.3389/fcell.2024.1383928
Holz A, Obi N, Ahrens W, Berger K, Bohn B, Brenner H, Fischer B, Fricke J, Führer A, Gastell S, Greiser KH, Harth V, Heise JK, Holleczek B, Keil T, Klett-Tammen CJ, Leitzmann M, Lieb W, Meinke-Franze C, Michels KB, Mikolajczyk R, Nimptsch K, Peters A, Pischon T, Riedel O,
Schikowski T
, Schipf S, Schmidt B, Schulze MB, Stang A, Hellwig K, Riemann-Lorenz K, Heesen C, Becher H:
Childhood and adolescence factors and multiple sclerosis: results from the German National Cohort (NAKO)
.
BMC Neurol
24(1): 123, 2024. doi: 10.1186/s12883-024-03620-4
Passeron T, Dreno B, Puig S, Goh CL, Kang HY, Ly F, Morita A, Ocampo Candiani J, Schalka S, Wei L, Demessant-Flavigny AL, Le Floc’h C, Kerob D, Lim HW,
Krutmann J:
Outdoor workers and sun exposure: Results of an international survey on sun exposure behaviours and knowledge among 17 countries, the HELIOS project
.
J Eur Acad Dermatol Venereol,
2024. doi: 10.1111/jdv.20001
Szepanowski LP
, Wruck W,
Kapr J
,
Rossi A
,
Fritsche E
,
Krutmann J
, Adjaye J:
Cockayne syndrome patient iPSC-derived brain organoids and neurospheres show early transcriptional dysregulation of biological processes associated with brain development and metabolism
.
Cells
13(7): 591, 2024. doi: 10.3390/cells13070591
Binder S
,
Ramachandran H
, Haslinger D, Hildebrandt B,
Dobner J
,
Haarmann-Stemmann T
, Chiocchetti A,
Rossi A:
CRISPR/Cas9-mediated editing of ACTB in induced pluripotent stem cells: A model for investigating human ACTB loss-of-function and genetic adaptive responses
.
Stem Cell Res
77:103395, 2024. doi: 10.1016/j.scr.2024.103395
Bredeck G
,
Dobner J
,
Rossi A
,
Schins RPF
:
Saharan dust induces the lung disease-related cytokines granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor.
Environ Int
186: 108580, 2024. doi: 10.1016/j.envint.2024.108580
Dobner J
,
Nguyen T
, Pavez-Giani MG, Cyganek L, Distelmaier F,
Krutmann J
, Prigione A,
Rossi A
:
mtDNA Analysis using Mitopore.
Mol Ther Methods Clin Dev
32(2): 101231, 2024. doi: 10.1016/j.omtm.2024.101231
Jaylet T, Coustillet T, Smith NM, Viviani B, Lindeman B, Vergauwen L, Myhre O, Yarar N, Gostner JM, Monfort-Lanzas P, Jornod F, Holbech H, Coumoul X, Sarigiannis DA, Antczak P, Bal-Price A,
Fritsche E
,
Kuchovska E
, Stratidakis AK, Barouki R, Kim MJ, Taboureau O, Wojewodzic MW, Knapen D, Audouze K:
Comprehensive mapping of the AOP-Wiki database: identifying biological and disease gaps
.
Front Toxicol
6: 1285768, 2024. doi: 10.3389/ftox.2024.1285768
Zhang R, Pu W, Zhang X, Di Y, Xu J, Zhu M, Tan Y, Liu W,
Krutmann J
, Wang J, Ma Y:
Blue light protection factor: a method to assess the protective efficacy of cosmetics against blue light-induced skin damage in the Chinese population
.
Photochem Photobiol Sci
23(4): 711-718, 2024. doi: 10.1007/s43630-024-00546-1
Dobner J
,
Nguyen T
, Dunkel A, Prigione A,
Krutmann J
,
Rossi A
:
Mitochondrial DNA integrity and metabolome profile are preserved in the human induced pluripotent stem cell reference line KOLF2.1J
.
Stem Cell Rep
19(3): 343-350, 2024. doi: 10.1016/j.stemcr.2024.01.009
Cibelli A, Mola MG, Saracino E, Barile B, Abbrescia P, Mogni G, Spray DC, Scemes E,
Rossi A
, Spennato D, Svelto M, Frigeri A, Benfenati V, Nicchia GP:
Aquaporin-4 and transient receptor potential vanilloid 4 balance in early postnatal neurodevelopment
.
Glia
72(5): 938-959, 2024. doi: 10.1002/glia.24512
Herbolsheimer F, Peters A, Wagner S, Willich SN, Krist L, Pischon T, Nimptsch K, Gastell S, Brandes M, Brandes B,
Schikowski T
, Schmidt B, Michels KB, Mikolajczyk R, Harth V, Obi N, Castell S, Heise JK, Lieb W, Franzpötter K, Karch A, Teismann H, Völzke H, Meinke-Franze C, Leitzmann M, Stein MJ, Brenner H, Holleczek B, Weber A, Bohn B, Kluttig A, Steindorf K:
Changes in physical activity and sedentary behavior during the first COVID-19 pandemic- restrictions in Germany: a nationwide survey.
BMC Public Health
24: 433, 2024. https://doi.org/10.1186/s12889-024-17675-y
Diemar MG, Vinken M, Teunis M, Krul CAM, Busquet F, Zajac JD, Kandarova H, Corvi R, Rosso MZ, Kharina A, Bryndum LS, Santillo M, Bloch D, Kucheryavenko O, Panagiotakos D, Rogiers V, Beekhuijzen M, Giusti A, Najjar A, Courage C, Koenig T, Kolle S, Boonen H, Dhalluin S, Boberg J, Müller BP, Kukic P, Ritskes-Hoitinga M, Grasselli E, Zietek T, Stoddart G, Heusinkveld HJ, Castell JV, Benfenati E, Yang H, Perera S, Paini A, Kramer NI, Hartung T, Janssen M, Fritsche E, Jennen DGJ, Piumatti M, Rathman J, Marusczyk J, Milec L, Roggen EL: Report of the first ONTOX stakeholder network meeting: Digging under the surface of ONTOX together with the stakeholders. Altern Lab Anim 52(2): 117-131, 2024. doi: 10.1177/02611929231225730
Liu BP, Huxley RR,
Schikowski T
, Hu KJ, Zhao Q, Jia CX:
Exposure to residential green and blue space and the natural environment is associated with a lower incidence of psychiatric disorders in middle-aged and older adults: findings from the UK Biobank
.
BMC Med
22: 15, 2024. https://doi.org/10.1186/s12916-023-03239-1
Limke A
, Poschmann G, Stühler K, Petzsch P, Wachtmeister T,
von Mikecz A
:
Silica nanoparticles disclose a detailed neurodegeneration profile throughout the life span of a model organism
.
J Xenobiotics
14(1): 135-153, 2024. doi: 10.3390/jox14010008
Binder S
,
Ramachandran H
, Hildebrandt B,
Dobner J
,
Rossi A:
Prime-Editing of human ACTB in induced pluripotent stem cells to model human ACTB Loss-of-Function diseases and compensatory mechanisms
.
Stem Cell Res
75:103304, 2024. doi: 10.1016/j.scr.2024.103304
Sortieren:
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All
2023
Areal AT
,
Singh N,
Zhao Q
, Berdel D, Koletzko S, von Berg A, Gappa M, Heinrich J, Standl M, Abramson MJ,
Schikowski T
:
The influence of short-term weather parameters and air pollution on adolescent airway inflammation.
Int J Environ Res Public Health
20(19): 6827, 2023. doi: 10.3390/ijerph20196827
Areal AT
,
Singh N
,
Zhao Q
, Berdel D, Koletzko S, von Berg A, Gappa M, Heinrich J, Standl M,
Schikowski T
:
The association of relative humidity and air pollution interaction on lung function in adolescents.
Front Environ Health
2: 1250523, 2023. doi: 10.3389/fenvh.2023.1250523
Bartmann K
,
Bendt F
,
Dönmez A
, Haag D,
Keßel HE
,
Masjosthusmann S
, Noel C, Wu J, Zhou P,
Fritsche E
:
A human iPSC-based in vitro neural network formation assay to investigate neurodevelopmental toxicity of pesticides
.
ALTEX
40(3): 452–470, 2023. doi: 10.14573/altex.2206031
Bernhard GH, Madronich S, Lucas RM, Byrne SN,
Schikowski T
, Neale RE:
Linkages between COVID-19, solar UV radiation, and the Montreal Protocol.
Photochem Photobiol Sci
22(5): 991-1009, 2023. doi: 10.1007/s43630-023-00373-w
Bloch S, Lévêque L, Hertz-Picciotto I, Puschner B,
Fritsche E
,
Klose J
, I Kramer N, Bouchard MF, Chandrasekera PC, Verner MA:
Using in vitro data to derive acceptable exposure levels: A case study on PBDE developmental neurotoxicity.
Environ Int 183: 108411, 2024 (online 2023). doi: 10.1016/j.envint.2023.108411
Bredeck G
,
Busch M
,
Rossi A
, Stahlmecke B, Fomba KW, Herrmann H,
Schins RPF
:
Inhalable Saharan dust induces oxidative stress, NLRP3 inflammasome activation, and inflammatory cytokine release
.
Environ Int
172: 107732, 2023. doi: 10.1016/j.envint.2023.107732
Bredeck G
,
Dobner J
, Stahlmecke B, Fomba KW, Herrmann H,
Rossi A
,
Schins RPF
:
Saharan dust induces NLRP3-dependent inflammatory cytokines in an alveolar air-liquid interface co-culture model
.
Part Fibre Toxicol
20: 39, 2023. doi: 10.1186/s12989-023-00550-w
Budu-Aggrey A, …,
Schikowski T
, …, Paternoster L:
European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.
Nat Commun
14: 6172, 2023. doi: 10.1038/s41467-023-41180-2
Busch M, Brouwer H, Aalderink G,
Bredeck G
,
Kämpfer AAM
,
Schins RPF
, Bouwmeester H:
Investigating nanoplastics toxicity using advanced stem cell-based intestinal and lung
in vitro
models
.
Front Toxicol
5: 1112212, 2023. doi: 10.3389/ftox.2023.1112212
Cadenas E,
Sies H
:
Lester Packer: On his life and his legacy
.
Antioxid Redox Signal
38(10-12): 768-774, 2023. doi: 10.1089/ars.2022.0097
Cai C, Zeng B, Lin L, Zheng M, Burki C,
Grether-Beck S
,
Krutmann J
:
An oral French maritime pine bark extract improves hair density in menopausal women: A randomized, placebo-controlled, double blind intervention study
.
Health Sci Rep
6(1): e1045, 2023. doi: 10.1002/hsr2.1045
Choudhary RK, Joshi P, Ghosh S, Ganguly D, Balakrishnan K,
Singh N
, Mall RK, Kumar A, Dey S:
Excess mortality risk due to heat stress in different climatic zones of India
.
Environ Sci Technol
, 58(1):342-351, 2024 (online 2023). doi: 10.1021/acs.est.3c05218
Clahsen T, Hadrian K, Notara M, Schlereth SL, Howaldt A, Prokosch V, Volatier T, Hos D, Schroedl F, Kaser-Eichberger A, Heindl LM, Steven P, Bosch JJ, Steinkasserer A, Rokohl AC, Liu H, Mestanoglu M, Kashkar H, Schumacher B, Kiefer F, Schulte-Merker S, Matthaei M, Hou Y,
Fassbender S
, Jantsch J, Zhang W, Enders P, Bachmann B, Bock F, Cursiefen C:
The novel role of lymphatic vessels in the pathogenesis of ocular diseases
.
Prog Retin Eye Res
96: 101157, 2023. doi: 10.1016/j.preteyeres.2022.101157
De Castelbajac T, Aiello K, Arenas CG, Svingen T, Ramhøj L, Zalko D, Barouki R, Vanhaecke T, Rogiers V, Audebert M, Oelgeschlaeger M, Braeuning A, Blanc E, Tal T, Rüegg J,
Fritsche E
, Marx-Stoelting P, Rivière G:
Innovative tools and methods for toxicity testing within PARC work package 5 on hazard assessment
.
Front Toxicol
5:1216369, 2023. doi: 10.3389/ftox.2023.1216369
Dobner J
,
Rossi A
:
Moderne Sequenzierungstechnologien und ihre Anwendungen
.
Biospektrum
29, 479–4822023. doi: 10.1007/s12268-023-1989-5
Dönmez A
:
On the ambiguity in classification
.
NeurIPS Workshop on Symmetry and Geometry in Neural Representations,
Proc Mach Learn Res
197: 158-170, 2023
Granger C, Passeron T, Trullas C, Hosenally M, Sokeechand BN,
Krutmann J
, Lim HW:
Outdoor clinical testing with reference sunscreens to determine differences in skin response between populations of different ethnicity: A combined data analysis from 128 subjects
.
Photodermatol Photoimmunol Photomed
, 39(5): 419-427, 2023. doi: 10.1111/phpp.12871
Granger C, Trullàs C, Sokeechand NB, Jourdan E,
Krutmann J
, Francois-Newton V, Hosenally M:
Evaluating the factors influencing sun protection factors (SPF): Pooling data from multiple studies involving two reference ISO 24444:2019 sunscreen products (P2 and P8)
.
Photodermatol Photoimmunol Photomed
40:e12942, 2024. doi:10.1111/phpp.12942
Haendeler J* and
Ventura N
*:
Role of mitochondria in environmentally and dietary modulated age-associated diseases
.
Cells
12: 404, 2023. doi:10.3390/cells12030404
Hartmann J
,
Henschel N
,
Bartmann K
,
Dönmez A
,
Brockerhoff G
,
Koch K
,
Fritsche E
:
Molecular and functional characterization of different BrainSphere models for use in neurotoxicity testing on microelectrode arrays
.
Cells
12(9): 1270, 2023. doi: 10.3390/cells12091270
Kado SY, Bein K, Castaneda AR, Pouraryan AA, Garrity N, Ishihara Y,
Rossi A
,
Haarmann-Stemmann T
, Sweeney C, Vogel CFA:
Regulation of IDO2 by the aryl hydrocarbon receptor (AhR) in breast cancer
.
Cells
12(10): 1433, 2023. doi: 10.3390/cells12101433
Kessel HE
,
Masjosthusmann S
,
Bartmann K
, Blum J,
Dönmez A
, Förster N,
Klose J
, Mosig A,
Pahl M
, Leist M, Scholze M,
Fritsche E
:
The impact of biostatistics on hazard characterization using in vitro developmental neurotoxicity assays
.
ALTEX
40(4): 619–634, 2023. doi: 10.14573/altex.2210171
Koch K
:
Editorial: Rising stars in neurotoxicology: 2021
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Front Toxicol
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Psychopathological symptoms as precursors of depressive symptoms in adolescence: a prospective analysis of the GINIplus and LISA birth cohort studies
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Soc Psychiatry Psychiatr Epidemiol
57(8): 1627-1639, 2022. doi: 10.1007/s00127-022-02267-1
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Eur Respir Rev
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Adv Mater Interfaces
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Cell Biol Toxicol
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Front Toxicol
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The role of polygenic susceptibility on air pollution-associated asthma between German and Japanese elderly women
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Int J Environ Res Public Health
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Sci Total Environ
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Respir Res
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Environmental Dermatitis
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Br J Dermatol
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Food Chem Toxicol
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BMC Bioinformatics
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J Cosmet Dermatol
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Liu W,
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Cells
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Allergy
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Altern Lab Anim
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Nucleic Acids Res
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J Invest Dermatol
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Peters A, German National Cohort (NAKO) Consortium; …, Schikowski T, …:
Framework and baseline examination of the German National Cohort (NAKO)
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Eur J Epidemiol
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Development and characterisation of an irradiation device for biomedical studies covering the solar spectrum with individual regulated spectral bands
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Photochem Photobiol Sci
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Front Public Health
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Environ Pollut
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Front Cell Dev Biol
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Schröter L
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Nat Rev Mol Cell Biol
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Part Fibre Toxicol
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Biochem Pharmacol
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RNA-based generation of iPSCs from a boy carrying the mutation m.9185 T>C in the mitochondrial gene MT-ATP6 and from his healthy mother
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Stem Cell Res
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Carbon nanoparticles adversely affect CFTR expression and toxicologically relevant pathways
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Sci Rep
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Sonnenschutz: Wichtiger denn je!
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Hautarzt
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Front Toxicol
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Int J Environ Res Public Health
19(17): 10880, 2022. doi: 10.3390/ijerph191710880
Tham M, Stark H-J, Jauch A, Harwood C,
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Front Oncol
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Uhlmann C, Nickel AC, Picard D,
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Progenitor cells derived from gene-engineered human induced pluripotent stem cells as synthetic cancer cell alternatives for in vitro pharmacology
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Biotechnol J
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Stem Cell Res
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A gene variant of AKR1C3 contributes to interindividual susceptibilities to atopic dermatitis triggered by particulate air pollution
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Allergy
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Front Genet
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Front Oncol
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Nature
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Sleep Med
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Wei Q, Li Z, Gu Z, Liu X,
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Front Microbiol
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Estimating the relative contribution of environmental and genetic risk factors to different aging traits by combining correlated variables into weighted risk scores
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Int J Environ Res Public Health
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Front Oncol
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Ale-Agha N, Jakobs P,
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von Ameln F
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, Brack F, Grandoch M, Thielmann M, Kamler M, Gedik N, Kleinbongard P, Heinen A, Heusch G, Gödecke A,
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Mitochondrial telomerase reverse transcriptase protects from myocardial ischemia/reperfusion injury by improving complex I composition and function
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.
Chest
160(1): 249-258, 2021. doi: 10.1016/j.chest.2021.02.007
Zhao Q
,
Wigmann C
,
Areal AT
,
Altug H
,
Schikowski T
:
Effect of non-optimum ambient temperature on cognitive function of elderly women in Germany.
Environ Pollut
285: 117474, 2021. doi: 10.1016/j.envpol.2021.117474
Zhao T, Triebner K, Markevych I, Standl M,
Altug H
, de Hoogh K,
Schikowski T
, Berdel D, Koletzko S, Bauer CP, von Berg A, Nowak D, Heinrich J:
Outdoor air pollution and hormone-assessed pubertal development in children: Results from the GINIplus and LISA birth cohorts
.
Environ Int
152: 106476, 2021. doi: 10.1016/j.envint.2021.106476
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Datum
Richtung
ASC
DESC
All
2020
Abramson MJ,
Wigmann C
,
Altug H
,
Schikowski T
:
Ambient air pollution is associated with airway inflammation in older women: a nested cross-sectional analysis.
BMJ Open Respir Res
7: e000549, 2020. doi: 10.1136/bmjresp-2019-000549
Alkotob SS, Cannedy C, Harter K, Movassagh H, Paudel B, Prunicki M, Sampath V,
Schikowski T
, Smith E,
Zhao Q
, Traidl-Hoffmann C, Nadeau KC:
Advances and novel developments in environmental influences on the development of atopic diseases.
Allergy
75(12): 3077-3086, 2020. doi: 10.1111/all.14624
Altuğ H
,
Fuks KB
,
Hüls A
, Mayer AK, Tham R,
Krutmann J
,
Schikowski T
:
Air pollution is associated with depressive symptoms in elderly women with cognitive impairment.
Environ Int
136: 105448, 2020. doi: 10.1016/j.envint.2019.105448
Barenys M
, Illa M,
Hofrichter M
, Loreiro C, Pla L,
Klose J
, Kühne BA, Gómez-Catalán J,
Braun JM
, Crispi F, Gratacós E,
Fritsche E
:
Rabbit neurospheres as a novel in vitro tool for studying neurodevelopmental effects induced by intrauterine growth restriction.
Stem Cells Transl Med
10(2): 209-221, 2021 (online 2020). doi: 10.1002/sctm.20-0223
Baswan SM,
Marini A
, Klosner AE,
Jaenicke T
, Leverett J, Murray M, Gellenbeck KW,
Krutmann J
:
Orally administered mixed carotenoids protect human skin against ultraviolet A-induced skin pigmentation: A double-blind, placebo-controlled, randomized clinical trial.
Photodermatol Photoimmunol Photomed
36(3): 219-225, 2020. doi: 10.1111/phpp.12541
Bernhard GH, Neale RE, Barnes PW, Neale PJ, Zepp RG, Wilson SR, Andrady AL, Bais AF, McKenzie RL, Aucamp PJ, Young PJ, Liley JB, Lucas RM, Yazar S, Rhodes LE, Byrne SN, Hollestein LM, Olsen CM, Young AR, Robson TM, Bornman JF, Jansen MAK, Robinson SA, Ballaré CL, Williamson CE, Rose KC, Banaszak AT, Häder DP, Hylander S, Wängberg SÅ, Austin AT, Hou WC, Paul ND, Madronich S, Sulzberger B, Solomon KR, Li H,
Schikowski T
, Longstreth J, Pandey KK, Heikkilä AM, White CC:
Environmental effects of stratospheric ozone depletion, UV radiation and interactions with climate change: UNEP Environmental Effects Assessment Panel, update 2019.
Photochem Photobiol Sci
19(5): 542-584, 2020. doi: 10.1039/d0pp90011g
Boots AW
, Veith C,
Albrecht C
, Bartholome R, Drittij MJ, Claessen SMH, Bast A, Rosenbruch M, Jonkers L, van Schooten FJ,
Schins RPF
:
The dietary antioxidant quercetin reduces hallmarks of bleomycin-induced lung fibrogenesis in mice.
BMC Pulm Med
20: 112, 2020. doi: 10.1186/s12890-020-1142-x
Brinkmann V
, Ale-Agha N, Haendeler J,
Ventura N
:
The Aryl hydrocarbon Receptor (AhR) in the aging process: Another puzzling role for this highly conserved transcription factor.
Front Physiol
10: 1561, 2020. doi: 10.3389/fphys.2019.01561
Brinkmann V,
Schiavi A
,
Shaik A
,
Puchta DR
,
Ventura N
:
Dietary and environmental factors have opposite AhR-dependent effects on
C. elegans
healthspan.
Aging (Albany NY)
13(1): 104-133, 2020. doi: 10.18632/aging.202316
Busch M
,
Bredeck G
,
Kämpfer AAM
,
Schins RPF
:
Investigations of acute effects of polystyrene and polyvinyl chloride micro- and nanoplastics in an advanced in vitro triple culture model of the healthy and inflamed intestine.
Environ Res
193: 110536, 2021 (online 2020). doi: 10.1016/j.envres.2020.110536
Dahlem C, Kado SY, He F, Bein K, Wu D,
Haarmann-Stemmann T
, Kado NY, Vogel CFA:
AHR signaling interacting with nutritional factors regulating the expression of markers in vascular inflammation and atherogenesis.
Int J Mol Sci
21(21): 8287, 2020. doi: 10.3390/ijms21218287
Esser C
, Boots AM, Caignard A, Ciraci C, Grčević D, Knapp S, Montoya M, Di Rosa F, Saksida T, Stravinskiene D, Deniz G:
The impact of COVID-19 lock-downs for European (female) immunologists – our views as members of the EFIS gender and diversity task force.
Euro J Immunol
50(12): 1855-1862, 2020. doi: 10.1002/eji.202070125
Esser C
,
Hochrath K
,
Schikowski T
,
Haarmann-Stemmann T
:
COVID-19 research: toxicological input urgently needed!
Arch Toxicol
94(7): 2547-2548, 2020. doi: 10.1007/s00204-020-02803-5
Feng X, Flexeder C, Markevych I, Standl M, Heinrich J,
Schikowski T
, Koletzko S, Herberth G, Bauer CP, von Berg A, Berdel D, Astell-Burt T:
Impact of residential green space on sleep quality and sufficiency in children and adolescents residing in Australia and Germany.
Int J Environ Res Public Health
17(13): 4894, 2020. doi: 10.3390/ijerph17134894
Fischer I, Nickel A-C, Qin N, Taban K, Pauck D, Steiger H-J, Kamp M, Muhammad S, Hänggi D,
Fritsche E
, Remke M, Kahlert UD:
Different calculation strategies are congruent in determining chemotherapy resistance of brain tumors in vitro.
Cells
9(12): 2689, 2020. doi: 10.3390/cells9122689
Fritsche E
,
Haarmann-Stemmann T,
Kapr J
,
Galanjuk S
,
Hartmann J
, Mertens PR,
Kämpfer AAM,
Schins RPF
,
Tigges J,
Koch K
:
Stem cells for next level toxicity testing in the 21st century.
Small
17(15): e2006252, 2021 (online 2020). doi: 10.1002/smll.202006252
Fritsche E
, Hogberg HT:
A brainer on neurotoxicity.
Frontiers in Toxicol
2: 3, 2020. doi: 10.3389/ftox.2020.00003
Gappa M, Filipiak-Pittroff B, Libuda L, von Berg A, Koletzko S, Bauer CP, Heinrich J,
Schikowski T
, Berdel D, Standl M:
Long-term effects of hydrolyzed formulae on atopic diseases in the GINI study.
Allergy
76(6): 1903-1907, 2021 (online 2020). doi: 10.1111/all.14709
Ghashghaei O, Pedrola M, Seghetti F, Martin VV, Zavarce R, Babiak M, Novacek J, Hartung F,
Rolfes KM
,
Haarmann-Stemmann T
, Lavilla R:
Extended multicomponent reactions with indole aldehydes: Access to unprecedented polyheterocyclic scaffolds, ligands of the aryl hydrocarbon receptor.
Angew Chem Int Edit
60(5): 2603-2608, 2021 (online 2020). doi: 10.1002/anie.202011253
Häselbarth L
, Ouwens DM,
Teichweyde N
,
Hochrath K
,
Merches K
,
Esser C
:
The small chain fatty acid butyrate antagonizes the TCR-stimulation-induced metabolic shift in murine epidermal gamma delta T cells
.
EXCLI J
19: 334-350, 2020. doi: 10.17179/excli2020-1123
Hippe A, Braun SA, Oláh P, Gerber PA, Schorr A, Seeliger S, Hotz S, Jannasch K, Pivarci A, Buhren B, Schrumpf H, Kislat A, Bünemann E, Steinhoff M, Fischer J, Lira SA,
Boukamp P
, Hevezi P, Stoecklein NH, Hoffmann T, Alves F, Sleeman J, Bauer T, Klufa J, Amberg N, Sibilia M, Zlotnik A, Müller-Homey A, Homey B:
EGFR/Ras-induced CCL20 production modulates the tumour microenvironment.
Br J Cancer
123: 942-954, 2020. doi: 10.1038/s41416-020-0943-2
Kämpfer AAM
,
Busch M
,
Schins RPF
:
Advanced
in vitro
testing strategies and models of the intestine for nanosafety research.
Chem Res Toxicol
33(5): 1163-1178, 2020. doi: 10.1021/acs.chemrestox.0c00079
Klose J,
Tigges J,
Masjosthusmann S
,
Schmuck K
,
Bend F
,
Hübenthal U
, Petzsch P, Köhrer K,
Koch K
,
Fritsche E
:
TBBPA targets converging key events of human oligodendrocyte development resulting in two novel AOPs
.
ALTEX
38(2): 215-234, 2021 (online 2020). doi: 10.14573/altex.2007201
Kolling J
,
Tigges J
, Hellack B,
Albrecht C
,
Schins RP
:
Evaluation of the NLRP3 inflammasome activating effects of a large panel of TiO
2
nanomaterials in macrophages
.
Nanomaterials
10(9): 1876, 2020. doi: 10.3390/nano10091876
Krutmann J
, Berneburg M:
Lichtalterung (Photoaging) der Haut: Was gibt es Neues?
Hautarzt
72(1): 2-5, 2021 (online 2020). doi: 10.1007/s00105-020-04747-4
Krutmann J
, Passeron T, Gilaberte Y, Granger C, Leone G, Narda M, Schalka S, Trullas C, Masson P, Lim HW:
Photoprotection of the future: Challenges and opportunities.
J Eur Acad Dermatol Venereol
34(3): 447-454, 2020. doi: 10.1111/jdv.16030
Lademann J, Richter H, Patzelt A, Meinke MC, Gross I,
Grether-Beck S
,
Krutmann J
, Frazier L, Darvin ME:
Laser scanning microscopy for control of skin decontamination efficacy from airborne particulates using highly absorbent textile nanofiber material in combination with PEG-12 dimethicone.
Skin Res Technol
26(4): 558-563, 2020. doi: 10.1111/srt.12830
Lambert KA, Markevych I, Yang B-Y, Bauer C-P, Berdel D, von Berg A, Bergmann K-C, Lodge C, Koletzko S, Prendergast LA,
Schikowski T
, Schulz H, Werchan M, Heinrich J, Standl M, Erbas B:
Association of early life and acute pollen exposure with lung function and exhaled nitric oxide (FeNO).
A prospective study up to adolescence in the GINIplus and LISA cohort.
Sci Total Environ
763: 143006, 2021 (online 2020). doi: 10.1016/j.scitotenv.2020.143006
Lettieri-Barbato D,
Ventura N
, Faraonio K, Aquilano K:
Editorial: Advances in metabolic mechanisms of aging and its related diseases.
Front Physiol
11: 594974, 2020. doi: 10.3389/fphys.2020.594974
Lupu D, Andersson P, Bornehag CG, Demeneix B,
Fritsche E
, Gennings C, Lichtensteiger W, Leist M, Leonards PEG, Ponsonby AL, Scholze M, Testa G, Tresguerres JAF, Westerink RHS, Zalc B, Rüegg J:
The ENDpoiNTs project: Novel testing strategies for endocrine disruptors linked to developmental neurotoxicity.
Int J Mol Sci
21: 3978, 2020. doi: 10.3390/ijms21113978
Madhusudhan N, Pausan MR, Halwachs B, Durdević M, Windisch M, Kehrmann J, Patra V, Wolf P,
Boukamp P
, Moissl-Eichinger C, Cerroni L, Becker JC, Gorkiewicz G:
Molecular profiling of keratinocyte skin tumors links Staphylococcus aureus overabundance and increased human
β
-Defensin-2 expression to growth promotion of squamous cell carcinoma.
Cancers
(Basel) 12(3): 541, 2020. doi: 10.3390/cancers12030541
Masjosthusmann S
, Blum J,
Bartmann K
, Dolde X, Holzer A-K,
Stürzl L-C
,
Keßel EH
, Förster N,
Dönmez A
,
Klose J
,
Pahl M
, Waldmann T,
Bendt F
, Kisitu J, Suciu I,
Hübenthal U
, Mosig A, Leist M,
Fritsche E
:
Establishment of an priori protocol for the implementation and interpretation of an in-vitro testing battery for the assessment of developmental neurotoxicity.
EFSA Supporting Publications
17(10): 1938E, 2020. doi: 10.2903/sp.efsa.2020.EN-1938
Mekić S,
Wigmann C
, Gunn DA, Kayser M, Jacobs LC,
Schikowski T
, Nijsten T, Pardo LM:
Genetics of facial telangiectasia in the Rotterdam study; a genome-wide association study and candidate gene approach
.
J Eur Acad Dermatol Venereol
35(3): 749-754, 2021 (online 2020). doi: 10.1111/jdv.17014
Melén E, Standl M, Gehring U,
Altug H
, Antó JM, Berdel D, Bergström A, Bousquet J, Heinrich J, Koppelman GH, Kull I, Lupinek C, Markevych I,
Schikowski T
, Thiering E, Valenta R, van Hage M, von Berg A, Vonk JM, Wickman M, Wijga A, Gruzieva O:
Air pollution and IgE sensitization in 4 European birth cohorts – the MeDALL project.
J Allergy Clin Immunol
47(2): 713-722, 2021 (online 2020). doi: 10.1016/j.jaci.2020.08.030
Merches K
,
Schiavi A
, Weighardt H,
Steinwachs S
,
Teichweyde N
, Förster I,
Hochrath K
, Schumak B,
Ventura N
, Petzsch P, Köhrer K,
Esser C
:
AHR signaling dampens inflammatory signature in neonatal skin γδ T cells.
Int J Mol Sci
21(6): 2249, 2020. doi: 10.3390/ijms21062249
Negele L, Flexeder C, Koletzko S, Bauer CP, von Berg A, Berdel D,
Schikowski T
, Standl M, Peters A, Schulz H:
Association between objectively assessed physical activity and sleep quality in adolescence. Results from the GINIplus and LISA studies.
Sleep Med
72: 65-74, 2020. doi: 10.1016/j.sleep.2020.03.007
Nimtz L
,
Hartmann J
,
Tigges J
,
Masjosthusmann S
,
Schmuck M
,
Keßel E
, Theiss S, Köhrer K, Petzsch P, Adjaye J,
Wigmann C
, Wieczorek D, Hildebrandt B,
Bendt F
,
Hübenthal U
,
Brockerhoff G
,
Fritsche E
:
Characterization and application of electrically active neuronal networks established from human induced pluripotent stem cell-derived neural progenitor cells for neurotoxicity evaluation.
Stem Cell Res
45: 101761, 2020. doi: 10.1016/j.scr.2020.101761
Nothdurft S, Thumser-Henner C, Breitenbücher F, Okimoto RA, Dorsch M, Opitz CA, Sadik A,
Esser C
, Hölzel M, Asthana S, Forster J, Beisser D, Kalmbach S, Grüner BM, Bivona TG, Schramm A, Schuler M:
Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis.
Oncogenesis
9(11): 102, 2020. doi: 10.1038/s41389-020-00286-8
Passeron T,
Krutmann J
, Andersen ML, Katta R, Zouboulis CC:
Clinical and biological impact of the exposome on the skin
.
J Eur Acad Dermatol Venereol
34 (Suppl 4): 4-25, 2020. doi: 10.1111/jdv.16614
Pavez Loriè E
,
Boukamp P
:
Methods in cell biology: Cell-derived matrices
.
Methods Cell Biol
156: 309-332, 2020. doi: 10.1016/bs.mcb.2019.11.012
Pavez-Lorie E
, Stricker N, Plitta-Michalak B, Peng-Chen I, Volkmer B, Greinert R, Jauch A,
Boukamp P
, Rapp A:
Characterisation of the novel spontaneously immortalized and invasively growing human skin keratinocyte line HaSKpw.
Sci Rep
10(1): 15196, 2020. doi: 10.1038/s41598-020-71315-0
Pemp D, Geppert LN,
Wigmann C
, Kleider C, Hauptstein R, Schmalbach K, Ickstadt K, Esch HL, Lehmann L:
Influence of breast cancer risk factors and intramammary biotransformation on estrogen homeostasis in the human breast.
Arch Toxicol
94(9): 3013-3025, 2020. doi: 10.1007/s00204-020-02807-1
Peters A, Rospleszcz S, Greiser KH, Dallavalle M, …,
Schikowski T
, …, Berger K; Complete list of authors available under: Collaborators.
The impact of the COVID-19 pandemic on self-reported health
.
Dtsch Arztebl Int
117(50): 861-867, 2020. doi: 10.3238/arztebl.2020.0861
Samoli E, Rodopoulou S, Schneider A, Morawska L, Stafoggia M, Renzi M, Breitner S, Lanki T, Pickford R,
Schikowski T
, Okokon E, Zhang S,
Zhao Q
, Peters A:
Meta-analysis on short-term exposure to ambient ultrafine particles and respiratory morbidity.
Eur Respir Rev
29(158): 200116, 2020. doi: 10.1183/16000617.0116-2020
Schiavi A
, Strappazzon F,
Ventura N
:
Mitophagy and iron: two actors sharing the stage in age-associated neuronal pathologies.
Mech Ageing Dev
188: 111252, 2020. doi: 10.1016/j.mad.2020.111252
Schikowski T
,
Altug H
:
The role of air pollution in cognitive impairment and decline
.
Neurochem Int
136: 104708, 2020. doi: 10.1016/j.neuint.2020.104708
Schikowski T
, Hüls A:
Air pollution and skin aging
.
Curr Environ Health Rep
7(1): 58-64, 2020. doi: 10.1007/s40572-020-00262-9
Schikowski T*
,
Wigmann C*
,
Fuks KB*
, et al.:
Blutdruckmessung in der NAKO – methodische Unterschiede, Blutdruckverteilung und Bekanntheit der Hypertonie im Vergleich zu anderen bevölkerungsbezogenen Studien in Deutschland.
[Blood pressure measurement in the NAKO German National Cohort (GNC) – differences in methods, distribution of blood pressure values, and awareness of hypertension compared to other population-based studies in Germany]
Bundesgesundheitsblatt-Gesund
63(4): 452-464, 2020. doi: 10.1007/s00103-020-03109-8 (* equal contribution)
Sies H
:
Findings in redox biology: from H
2
O
2
to oxidative stress.
J Biol Chem
295(39): 13458-13473, 2020. doi: 10.1074/jbc.X120.015651
Sies H
, Jones DP:
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents.
Nat Rev Mol Cell Biol
21(7): 363-383, 2020. doi: 10.1038/s41580-020-0230-3
Sies H
:
Oxidative stress: Concept and some practical aspects.
Antioxidants
9(9): 852, 2020. doi: 10.3390/antiox9090852
Sies H
, Parnham MJ:
Potential therapeutic use of ebselen for COVID-19 and other respiratory viral infections
.
Free Radic Biol Med
156: 107-112, 2020. doi: 10.1016/j.freeradbiomed.2020.06.032
Sies H
:
Schrödingers Koffer.
BIOspektrum
26: 345-346, 2020. doi: 10.1007/s12268-020-1364-8
Strom A, Strassburger K,
Schmuck M
, Shevalye H, Davidson E, Zivehe F, Bönhof G, Reimer R, Belgardt BF, Fleming T, Biermann B, Burkart V, Müssig K, Szendroedi J, Yorek MA,
Fritsche E
, Nawroth PP, Roden M, Ziegler D; GDS Group:
Interaction between magnesium and methylglyoxal in diabetic polyneuropathy and neuronal models.
Mol Metab
43: 101114, 2021 (online 2020). doi: 10.1016/j.molmet.2020.101114
Tan Y, Wang F, Fan G, Yan Z, Li B, Li N, Liu Y, Wang X, Liu W,
Krutmann J
, Zou Y, Wang S:
Identification of factors associated with minimal erythema dose variations in a large-scale population study of 22 146 subjects.
J Eur Acad Dermatol Venereol
34(7): 1595-1600, 2020. doi: 10.1111/jdv.16206
Thurston GD, Balmes JR, Garcia E, Gilliland FD, Rice MB,
Schikowski T
, Van Winkle LS, Annesi-Maesano I, Burchard EG, Carlsten C, Harkema JR, Khreis H, Kleeberger SR, Kodavanti UP, London SJ, McConnell R, Peden DB, Pinkerton KE, Reibman J, White CW:
Outdoor air pollution and new-onset airway disease.
An official American Thoracic Society workshop report.
Ann Am Thorac Soc
17(4): 387-398, 2020. doi: 10.1513/AnnalsATS.202001-046ST
Tsiampali J, Neumann S, Giesen B,
Koch K
, Maciaczyk D, Janiak C, Hänggi D, Maciaczyk J:
Enzymatic activity of CD73 modulates invasion of gliomas via epithelial-mesenchymal transition-like reprogramming
.
Pharmaceuticals
13(11): 378, 2020. doi: 10.3390/ph13110378
Vargas-Toscano A, Nickel A-C, Li G, Kamp MA, Muhammad S, Leprivier G,
Fritsche E
, Barker RA, Sabel M, Steiger HJ, Zhang W, Hänggi D, Kahlert UD:
Rapalink-1 targets glioblastoma stem cells and acts synergistically with tumor treating fields to reduce resistance against temozolomide.
Cancers
12(12): 3859, 2020. doi: 10.3390/cancers12123859
Vogel CFA, Van Winkle LS,
Esser C
,
Haarmann-Stemmann T
:
The aryl hydrocarbon receptor as a target of environmental stressors – Implications for pollution mediated stress and inflammatory responses.
Redox Biol
34: 101530, 2020. doi: 10.1016/j.redox.2020.101530
von Mikecz A
,
Schikowski T
:
Effects of airborne nanoparticles on the nervous system: amyloid protein aggregation, neurodegeneration and neurodegenerative diseases
.
Nanomaterials
10(7): 1349, 2020. doi: 10.3390/nano10071349
Wahle T
,
Sofranko A
, Dekkers S, Miller MR, Heusinkveld HJ,
Albrecht C
, Cassee FR,
Schins RPF
:
Evaluation of neurological effects of cerium dioxide nanoparticles doped with different amounts of zirconium following inhalation exposure in mouse models of Alzheimer’s and vascular disease
.
Neurochem Int
138: 104755, 2020. doi: 10.1016/j.neuint.2020.104755
Wang Q,
Zhao Q
, Wang G, Wang B, Zhang Y, Zhang J, Li N, Zhao Y, Qiao H, Li W, Liu X, Liu L, Wang F, Zhang Y, Guo Y:
The association between ambient temperature and clinical visits for inflammation-related diseases in rural areas in China
.
Environ Pollut
261: 114128, 2020. doi: 10.1016/j.envpol.2020.114128
White A, Kanninen K, Malm T,
Schins RPF
:
Editorial: Air pollution and brain health.
Neurochem Int
141: 104900, 2020. doi: 10.1016/j.neuint.2020.104900
Zhao Q
,
Kress S
, Markevych I, Berdel D, von Berg A, Gappa M, Koletzko S, Bauer CP, Schulz H, Standl M, Heinrich J,
Schikowski T
:
Air pollution during infancy and lung function development into adolescence: The GINIplus/LISA birth cohorts study
.
Environ Int
146: 106195, 2021 (online 2020). doi: 10.1016/j.envint.2020.106195
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FF1
Dobner J
, Diecke S,
Krutmann J
, Prigione A,
Rossi A
:
Reassessment of marker genes in human induced pluripotent stem cells for enhanced quality control
.
Nat Commun
15(1):8547, 2024. doi: 10.1038/s41467-024-52922-1
Zhao Z, Chu J, Ren J, Xu C, Xu X, Cao Y,
Schikowski T
,
Zhao Q
, Liu Q, Chen G, Lu Z, Guo X, Ma W, Wang H, Ma J:
Effect modification of heat-related mortality risk by air pollutants in Shandong, China
.
Am J Trop Med Hyg
111(2):440-446, 2024. doi: 10.4269/ajtmh.23-0295
Madronich S, Bernhard GH, Neale PJ, Heikkilä A, Andersen MPS, Andrady AL, Aucamp PJ, Bais AF, Banaszak AT, Barnes PJ, Bornman JF, Bruckman LS, Busquets R, Chiodo G, Häder DP, Hanson ML, Hylander S, Jansen MAK, Lingham G, Lucas RM, Calderon RM, Olsen C, Ossola R, Pandey KK, Petropavlovskikh I, Revell LE, Rhodes LE, Robinson SA, Robson TM, Rose KC,
Schikowski T
, Solomon KR, Sulzberger B, Wallington TJ, Wang QW, Wängberg SÅ, White CC, Wilson SR, Zhu L, Neale RE:
Continuing benefits of the Montreal Protocol and protection of the stratospheric ozone layer for human health and the environment
.
Photochem Photobiol Sci
23(6): 1087-1115, 2024. doi: 10.1007/s43630-024-00577-8
Mikolajczyk R, Diexer S, Klee B, Pfrommer L, Purschke O, Fricke J, Ahnert P, Gabrysch S, Gottschick C, Bohn B, Brenner H, Buck C, Castell S, Gastell S, Greiser KH, Harth V, Heise JK, Holleczek B, Kaaks R, Keil T, Krist L, Leitzmann M, Lieb W, Meinke-Franze C, Michels KB, Velásquez IM, Obi N, Panreck L, Peters A, Pischon T,
Schikowski T
, Schmidt B, Standl M, Stang A, Völzke H, Weber A, Zeeb H, Karch A:
Likelihood of post-COVID condition in people with hybrid immunity; data from the German National Cohort (NAKO)
.
J Infect
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Kress S
, Lane TJ, Brown D, Smith CL, Gao CX, McCrabb T, Thomas M, Borg BM, Thompson BR, Abramson MJ:
Association between PM
2.5
from a coal mine fire and FeNO concentration 7.5 years later
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BMC Pulm Med
24(1): 272, 2024. doi: 10.1186/s12890-024-03075-w
Hara A, Sato T,
Kress S
, Suzuki K, Pham KO, Tajima A,
Schikowski T
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Sex-specific associations between air pollutants and asthma prevalence in Japanese adults: a population-based study
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Int J Environ Health Res
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Singh N
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Areal AT
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Schikowski T
, Schneider A:
Heat and cardiovascular mortality: An epidemiological perspective
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Circ Res
134(9): 1098-1112, 2024. doi: 10.1161/CIRCRESAHA.123.323615
Bredeck G
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Wigmann C
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Schins RPF:
The influence of long-range transported Saharan dust on the inflammatory potency of ambient PM
2.5
and PM
10
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Environ Res
252(3): 119008, 2024. doi: 10.1016/j.envres.2024.119008
Bredeck G
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Rossi A
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Schins RPF
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Saharan dust induces the lung disease-related cytokines granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor.
Environ Int
186: 108580, 2024. doi: 10.1016/j.envint.2024.108580
Dobner J
,
Nguyen T
, Pavez-Giani MG, Cyganek L, Distelmaier F,
Krutmann J
, Prigione A,
Rossi A
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mtDNA Analysis using Mitopore.
Mol Ther Methods Clin Dev
32(2): 101231, 2024. doi: 10.1016/j.omtm.2024.101231
Dobner J
,
Nguyen T
, Dunkel A, Prigione A,
Krutmann J
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Rossi A
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Mitochondrial DNA integrity and metabolome profile are preserved in the human induced pluripotent stem cell reference line KOLF2.1J
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Stem Cell Rep
19(3): 343-350, 2024. doi: 10.1016/j.stemcr.2024.01.009
Herbolsheimer F, Peters A, Wagner S, Willich SN, Krist L, Pischon T, Nimptsch K, Gastell S, Brandes M, Brandes B,
Schikowski T
, Schmidt B, Michels KB, Mikolajczyk R, Harth V, Obi N, Castell S, Heise JK, Lieb W, Franzpötter K, Karch A, Teismann H, Völzke H, Meinke-Franze C, Leitzmann M, Stein MJ, Brenner H, Holleczek B, Weber A, Bohn B, Kluttig A, Steindorf K:
Changes in physical activity and sedentary behavior during the first COVID-19 pandemic- restrictions in Germany: a nationwide survey.
BMC Public Health
24: 433, 2024. https://doi.org/10.1186/s12889-024-17675-y
Binder S
,
Ramachandran H
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Dobner J
,
Rossi A:
Prime-Editing of human ACTB in induced pluripotent stem cells to model human ACTB Loss-of-Function diseases and compensatory mechanisms
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Stem Cell Res
75:103304, 2024. doi: 10.1016/j.scr.2024.103304
Areal AT
,
Singh N
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Zhao Q
, Berdel D, Koletzko S, von Berg A, Gappa M, Heinrich J, Standl M,
Schikowski T
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The association of relative humidity and air pollution interaction on lung function in adolescents.
Front Environ Health
2: 1250523, 2023. doi: 10.3389/fenvh.2023.1250523
Silvonen V, Salo L, Raunima T, Vojtisek-Lom M, Ondracek J, Topinka J,
Schins RPF
, Lepistö T, Lintusaari H, Saarikoski S, Barreira L, Hoivala J, Markkula L, Kulmala I, Vinha J, Karjalainen P, Rönkkö T:
Lung-depositing surface area (LDSA) of particles in office spaces around Europe: Size-distributions, I/O-ratios and infiltration
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Build Environ
246:110999, 2023. doi: 10.1016/j.buildenv.2023.110999
Bredeck G
,
Dobner J
, Stahlmecke B, Fomba KW, Herrmann H,
Rossi A
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Schins RPF
:
Saharan dust induces NLRP3-dependent inflammatory cytokines in an alveolar air-liquid interface co-culture model
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Part Fibre Toxicol
20: 39, 2023. doi: 10.1186/s12989-023-00550-w
Areal AT
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Singh N,
Zhao Q
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Schikowski T
:
The influence of short-term weather parameters and air pollution on adolescent airway inflammation.
Int J Environ Res Public Health
20(19): 6827, 2023. doi: 10.3390/ijerph20196827
Lepistö T, Lintusaari H, Oudin A, Barreira LMF, Niemi JV, Karjalainen P, Salo L, Silvonen V, Markkula L, Hoivala J, Marjanen P, Martikainen S, Aurela M, Reyes Reyes F, Oyola P, Kuuluvainen H, Manninen HE,
Schins RPF
, Vojtisek-Lom M, Ondracek J, Topinka J, Timonen H, Jalava P, Saarikoski S, Rönkkö T:
Particle lung deposited surface area (LDSA
al
) size distributions in different urban environments and geographical regions: Towards understanding of the PM
2.5
dose–response.
Environ Int
180: 108224, 2023. doi: 10.1016/j.envint.2023.108224
Bernhard GH, Madronich S, Lucas RM, Byrne SN,
Schikowski T
, Neale RE:
Linkages between COVID-19, solar UV radiation, and the Montreal Protocol.
Photochem Photobiol Sci
22(5): 991-1009, 2023. doi: 10.1007/s43630-023-00373-w
Busch M, Brouwer H, Aalderink G,
Bredeck G
,
Kämpfer AAM
,
Schins RPF
, Bouwmeester H:
Investigating nanoplastics toxicity using advanced stem cell-based intestinal and lung
in vitro
models
.
Front Toxicol
5: 1112212, 2023. doi: 10.3389/ftox.2023.1112212
Bredeck G
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Busch M
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Rossi A
, Stahlmecke B, Fomba KW, Herrmann H,
Schins RPF
:
Inhalable Saharan dust induces oxidative stress, NLRP3 inflammasome activation, and inflammatory cytokine release
.
Environ Int
172: 107732, 2023. doi: 10.1016/j.envint.2023.107732
Zhao Z, Chu J, Xu X, Cao Y,
Schikowski T
, Geng M, Chen G, Bai G, Hu K, Xia J, Ma W, Liu Q, Lu Z, Guo X, Zhao Q:
Association between ambient cold exposure and mortality risk in Shandong Province, China: Modification effect of particulate matter size.
Front Public Health
10: 1093588, 2023. doi: 10.3389/fpubh.2022.1093588
Wigmann C
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Krutmann J
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Schikowski T
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Estimating the relative contribution of environmental and genetic risk factors to different aging traits by combining correlated variables into weighted risk scores
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Int J Environ Res Public Health
19(24): 16746, 2022. doi: 10.3390/ijerph192416746
Sies H
:
Oxidativer Stress, Eustress und Distress: H
2
O
2
als Signalmolekül
.
Biospektrum
28: 685–690, 2022. doi: 10.1007/s12268-022-1862-y
Peters A, German National Cohort (NAKO) Consortium; …, Schikowski T, …:
Framework and baseline examination of the German National Cohort (NAKO)
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Eur J Epidemiol
37(10): 1107-1124, 2022. doi: 10.1007/s10654-022-00890-5
Zhang S, Breitner S, Pickford R, Lanki T, Okokon E, Morawska L, Samoli E, Rodopoulou S, Stafoggia M, Renzi M,
Schikowski T
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Zhao Q
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Short-term effects of ultrafine particles on heart rate variability:
A systematic review and meta-analysis
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Environ Pollut
314: 120245, 2022. doi: 10.1016/j.envpol.2022.120245
Kress S
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Wigmann C
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Zhao Q
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Schikowski T
:
Chronic air pollution-induced subclinical airway inflammation and polygenic susceptibility
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Respir Res
23(1): 265, 2022. doi: 10.1186/s12931-022-02179-3
Stermann T
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Nguyen T
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Woeste S
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Hacheney I
,
Krutmann J
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Unfried K
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Schins RPF
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Rossi A
:
Carbon nanoparticles adversely affect CFTR expression and toxicologically relevant pathways
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Sci Rep
12(1): 14255, 2022. doi: 10.1038/s41598-022-18098-8
von Mikecz A
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Exposome, molecular pathways and one health: The invertebrate
Caenorhabditis elegans
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Int J Mol Sci
23(16): 9084, 2022. doi: 10.3390/ijms23169084
Dobner J
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Ramachandran H
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Rossi A
:
Genome editing in translational medicine: An inventory
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Front Biosci (Landmark Ed)
27(8): 241, 2022. doi: 10.31083/j.fbl2708241
Vogeley C
,
Nguyen T
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Woeste S
,
Krutmann J
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Haarmann-Stemmann T
,
Rossi A
:
Rapid and simple analysis of short and long sequencing reads using Duesselpore
TM
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Front Genet
13: 931996, 2022. doi: 10.3389/fgene.2022.931996
Gruzieva O, Jeong A, He S, Yu Z, de Bont J, Pinho MGM, Eze IC,
Kress S
, Wheelock CE, Peters A, Vlaanderen J, de Hoogh K, Scalbert A, Chadeau-Hyam M, Vermeulen RCH, Gehring U, Probst-Hensch N, Melén E:
Air pollution, metabolites and respiratory health across the life-course
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Eur Respir Rev
31(165): 220038, 2022. doi: 10.1183/16000617.0038-2022
Kress S
, Hara A,
Wigmann C
, Sato T, Suzuki K, Pham KO,
Zhao Q
,
Areal A
, Tajima A, Schwender H, Nakamura H,
Schikowski T
:
The role of polygenic susceptibility on air pollution-associated asthma between German and Japanese elderly women
.
Int J Environ Res Public Health
19(16): 9869, 2022. doi: 10.3390/ijerph19169869
Zhao T, Markevych I, Standl M, Lyu Z,
Schikowski T
, Berdel D, Koletzko S, von Berg A, Heinrich J:
Ambient ozone exposure and bone turnover markers in children: Results from the GINIplus and LISA birth cohorts
.
Environ Res
214(Pt 1): 113784, 2022. doi: 10.1016/j.envres.2022.113784
Kress S
, Kilanowski A,
Wigmann C
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Zhao Q
, Zhao T, Abramson MJ, Gappa M, Standl M,
Unfried K
,
Schikowski T
:
Airway inflammation in adolescents and elderly women: Chronic air pollution exposure and polygenic susceptibility
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Sci Total Environ
841: 156655, 2022. doi: 10.1016/j.scitotenv.2022.156655
Nguyen T
,
Ramachandran H
,
Martins S
,
Krutmann J
,
Rossi A
:
Identification of genome edited cells using CRISPRnano
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Nucleic Acids Res
50(W1): W199–203, 2022. doi: 10.1093/nar/gkac440
Borror MB, Girotti M, Kar A, Cain MK, Gao X, MacKay VL, Herron B, Bhaskaran S, Becerra S, Novy N,
Ventura N
, Johnson TE, Kennedy BK, Rea SL:
Inhibition of ATR reverses a mitochondrial respiratory insufficiency
.
Cells
11(11): 1731, 2022. doi: 10.3390/cells11111731
Elberskirch L,
Sofranko A
, Liebing J, Riefler N, Binder K, Bonatto Minella C, Razum M, Mädler L,
Unfried K
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Schins RPF
, Kraegeloh A, van Thriel C:
How structured meta data acquisition contributes to reproducibility of nanosafety studies: Evaluation by a Round-Robin Test
.
Nanomaterials
12(7): 1053, 2022. doi: 10.3390/nano12071053
Doak SH, Clift MJD, Costa A, Delmaar C, Gosens I, Halappanavar S, Kelly S, Pejinenburg WJGM, Rothen-Rutishauser B,
Schins RPF
, Stone V, Tran L, Vijver MG, Vogel U, Wohlleben W, Cassee FR:
The road to achieving the European Commission’s chemicals strategy for nanomaterial sustainability-A PATROLS perspective on new approach methodologies
.
Small
18(17): e2200231, 2022. doi: 10.1002/smll.202200231
Lau M
,
Wigmann C
,
Kress S
,
Schikowski T
, Schwender H:
Evaluation of tree-based statistical learning methods for constructing genetic risk scores
.
BMC Bioinformatics
23(1): 97, 2022. doi: 10.1186/s12859-022-04634-w
Rossi A
, Lickfett S,
Martins S
, Prigione A:
A call for consensus guidelines on monitoring the integrity of nuclear and mitochondrial genomes in human pluripotent stem cells
.
Stem Cell Rep
17(4): 707-710, 2022. doi: 10.1016/j.stemcr.2022.01.019
Sies H
, Belousov VV, Chandel NS, Davies MJ, Jones DP, Mann GE, Murphy MP, Yamamoto M, Winterbourn C:
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
.
Nat Rev Mol Cell Biol
23(7): 499-515, 2022. doi: 10.1038/s41580-022-00456-z
von Mikecz A
, Scharf A:
Pollution – bring the field into the lab
.
Nature
602(7897): 386, 2022. doi: 10.1038/d41586-022-00444-5
Elberskirch L, Binder K, Riefler N,
Sofranko A
, Liebing J, Bonatto Minella C, Mädler L, Razum M, van Thriel C,
Unfried K
,
Schins RPF
, Kraegeloh A:
Digital research data: from analysis of existing standards to a scientific foundation for a modular metadata schema in Nanosafety.
Part Fibre Toxicol
19: 1, 2022. doi: 10.1186/s12989-021-00442-x
Rossi A
, Kontarakis Z:
Beyond Mendelian inheritance: genetic buffering and phenotype variability
.
Phenomics
2: 79-87, 2022 (online 2021). doi: 10.1007/s43657-021-00030-1
Areal AT
,
Zhao Q
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Wigmann C
, Schneider A,
Schikowski T
:
The effect of air pollution when modified by temperature on respiratory health outcomes: A systematic review and meta-analysis
.
Sci Total Environ
811: 152336, 2022 (online 2021). doi: 10.1016/j.scitotenv.2021.152336
He Y, Jiang Y, Yang Y, Xu J, Zhang Y, Wang Q, Shen H, Zhang Y, Yan D, Peng Z, Liu C, Wang W,
Schikowski T
, Li H, Yan B, Ji JS, Chen A, van Donkelaar A, Martin R, Chen R, Kan H, Cai J, Ma X:
Composition of fine particulate matter and risk of preterm birth: A nationwide birth cohort study in 336 Chinese cities
.
J Hazard Mater
425: 127645, 2022 (online 2021). doi: 10.1016/j.jhazmat.2021.127645
Lanzinger S,
Altug H
,
Schikowski T
, Khodaverdi S, Rosenbauer J, Rathmann W, Praedicow K, Schönau E, Holl RW; DPV initiative:
Longitudinal relationship of particulate matter and metabolic control and severe hypoglycaemia in children and adolescents with type 1 diabetes
.
Environ Res
203: 111859, 2022 (online 2021). doi: 10.1016/j.envres.2021.111859
Sies H
, Ursini F:
Homeostatic control of redox status and health
.
IUBMB Life
74(1): 24-28, 2022 (online 2021). doi: 10.1002/iub.2519
Tigges J,
Bielec K
,
Brockerhoff G
, Hildebrandt B,
Hübenthal U
,
Kapr J
,
Koch K
,
Teichweyde N
, Wieczorek D,
Rossi A
,
Fritsche E
:
Academic application of Good Cell Culture Practice for induced pluripotent stem cells
.
ALTEX
38(4): 595-614, 2021. doi: 10.14573/altex.2101221
Ramachandran H
,
Martins S
, Kontarakis Z,
Krutmann J
,
Rossi A
:
Fast but not furious: a streamlined selection method for genome edited cells
.
Life Sci Alliance
4(6): e202101051, 2021. doi: 10.26508/lsa.202101051
Annesi-Maesano I, Forastiere F, Balmes J, Garcia E, Harkema J, Holgate S, Kelly F, Khreis H, Hoffmann B, Maesano CN, McConnell R, Peden D, Pinkerton K,
Schikowski T
, Thurston G, Van Winkle LS, Carlsten C:
The clear and persistent impact of air pollution on chronic respiratory diseases: a call for interventions.
Eur Respir J
57(3): 2002981, 2021. doi: 10.1183/13993003.02981-2020
Zhao T, Triebner K, Markevych I, Standl M,
Altug H
, de Hoogh K,
Schikowski T
, Berdel D, Koletzko S, Bauer CP, von Berg A, Nowak D, Heinrich J:
Outdoor air pollution and hormone-assessed pubertal development in children: Results from the GINIplus and LISA birth cohorts
.
Environ Int
152: 106476, 2021. doi: 10.1016/j.envint.2021.106476
Tacu I
, Kokalari I, Abollino O,
Albrecht C
, Malandrino M, Ferretti AM,
Schins RPF
, Fenoglio I:
Mechanistic insights into the role of iron, copper and carbonaceous component on the oxidative potential of ultrafine particulate matter
.
Chem Res Toxicol
34(3): 767-779, 2021. doi: 10.1021/acs.chemrestox.0c00399
Dalecká A,
Wigmann C
,
Kress S
,
Altug H
, Jiřík V, Heinrich J, Abramson MJ,
Schikowski T
:
The mediating role of lung function on air pollution-induced cardiopulmonary mortality in elderly women: The SALIA cohort study with 22-year mortality follow-up.
Int J Hyg Environ Health
233: 113705, 2021. doi: 10.1016/j.ijheh.2021.113705
Zhao Q
,
Kress S
, Markevych I, Berdel D, von Berg A, Gappa M, Koletzko S, Bauer CP, Schulz H, Standl M, Heinrich J,
Schikowski T
:
Long-term air pollution exposure under European Union limits and adolescents‘ lung function: Modifying effect of abnormal weight in the GINIplus and LISA birth cohorts
.
Chest
160(1): 249-258, 2021. doi: 10.1016/j.chest.2021.02.007
Llewellyn SV,
Kämpfer AAM
, Keller JG, Vilsmeier K,
Büttner V
, Seleci DA,
Schins RPF
, Doak SH, Wohlleben W:
Simulating nanomaterial transformation in cascaded biological compartments to enhance the physiological relevance of in vitro dosing regimes: Optional or required?
Small
17(15): e2004630, 2021. doi: 10.1002/smll.202004630
Sies H
:
Oxidative eustress: On constant alert for redox homeostasis.
Redox Biol
41: 101867, 2021. doi: 10.1016/j.redox.2021.101867
Kämpfer AAM
,
Busch B
,
Büttner V
,
Bredeck G
, Stahlmecke B, Hellack B,
Masson I
,
Albrecht C
,
Schins RP
:
Model complexity as determining factor for in vitro nanosafety studies – Effects of silver and titanium dioxide nanomaterials in intestinal models.
Small
17(15): e2004223, 2021. doi: 10.1002/smll.202004223
Busch M
,
Bredeck G
,
Kämpfer AAM
,
Schins RPF
:
Investigations of acute effects of polystyrene and polyvinyl chloride micro- and nanoplastics in an advanced in vitro triple culture model of the healthy and inflamed intestine.
Environ Res
193: 110536, 2021 (online 2020). doi: 10.1016/j.envres.2020.110536
Nothdurft S, Thumser-Henner C, Breitenbücher F, Okimoto RA, Dorsch M, Opitz CA, Sadik A,
Esser C
, Hölzel M, Asthana S, Forster J, Beisser D, Kalmbach S, Grüner BM, Bivona TG, Schramm A, Schuler M:
Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis.
Oncogenesis
9(11): 102, 2020. doi: 10.1038/s41389-020-00286-8
Esser C
, Boots AM, Caignard A, Ciraci C, Grčević D, Knapp S, Montoya M, Di Rosa F, Saksida T, Stravinskiene D, Deniz G:
The impact of COVID-19 lock-downs for European (female) immunologists – our views as members of the EFIS gender and diversity task force.
Euro J Immunol
50(12): 1855-1862, 2020. doi: 10.1002/eji.202070125
Samoli E, Rodopoulou S, Schneider A, Morawska L, Stafoggia M, Renzi M, Breitner S, Lanki T, Pickford R,
Schikowski T
, Okokon E, Zhang S,
Zhao Q
, Peters A:
Meta-analysis on short-term exposure to ambient ultrafine particles and respiratory morbidity.
Eur Respir Rev
29(158): 200116, 2020. doi: 10.1183/16000617.0116-2020
Zhao Q
,
Kress S
, Markevych I, Berdel D, von Berg A, Gappa M, Koletzko S, Bauer CP, Schulz H, Standl M, Heinrich J,
Schikowski T
:
Air pollution during infancy and lung function development into adolescence: The GINIplus/LISA birth cohorts study
.
Environ Int
146: 106195, 2021 (online 2020). doi: 10.1016/j.envint.2020.106195
Lambert KA, Markevych I, Yang B-Y, Bauer C-P, Berdel D, von Berg A, Bergmann K-C, Lodge C, Koletzko S, Prendergast LA,
Schikowski T
, Schulz H, Werchan M, Heinrich J, Standl M, Erbas B:
Association of early life and acute pollen exposure with lung function and exhaled nitric oxide (FeNO).
A prospective study up to adolescence in the GINIplus and LISA cohort.
Sci Total Environ
763: 143006, 2021 (online 2020). doi: 10.1016/j.scitotenv.2020.143006
Sies H
:
Findings in redox biology: from H
2
O
2
to oxidative stress.
J Biol Chem
295(39): 13458-13473, 2020. doi: 10.1074/jbc.X120.015651
Kolling J
,
Tigges J
, Hellack B,
Albrecht C
,
Schins RP
:
Evaluation of the NLRP3 inflammasome activating effects of a large panel of TiO
2
nanomaterials in macrophages
.
Nanomaterials
10(9): 1876, 2020. doi: 10.3390/nano10091876
Sies H
:
Oxidative stress: Concept and some practical aspects.
Antioxidants
9(9): 852, 2020. doi: 10.3390/antiox9090852
Sies H
, Parnham MJ:
Potential therapeutic use of ebselen for COVID-19 and other respiratory viral infections
.
Free Radic Biol Med
156: 107-112, 2020. doi: 10.1016/j.freeradbiomed.2020.06.032
Esser C
,
Hochrath K
,
Schikowski T
,
Haarmann-Stemmann T
:
COVID-19 research: toxicological input urgently needed!
Arch Toxicol
94(7): 2547-2548, 2020. doi: 10.1007/s00204-020-02803-5
Sies H
:
Schrödingers Koffer.
BIOspektrum
26: 345-346, 2020. doi: 10.1007/s12268-020-1364-8
Boots AW
, Veith C,
Albrecht C
, Bartholome R, Drittij MJ, Claessen SMH, Bast A, Rosenbruch M, Jonkers L, van Schooten FJ,
Schins RPF
:
The dietary antioxidant quercetin reduces hallmarks of bleomycin-induced lung fibrogenesis in mice.
BMC Pulm Med
20: 112, 2020. doi: 10.1186/s12890-020-1142-x
Thurston GD, Balmes JR, Garcia E, Gilliland FD, Rice MB,
Schikowski T
, Van Winkle LS, Annesi-Maesano I, Burchard EG, Carlsten C, Harkema JR, Khreis H, Kleeberger SR, Kodavanti UP, London SJ, McConnell R, Peden DB, Pinkerton KE, Reibman J, White CW:
Outdoor air pollution and new-onset airway disease.
An official American Thoracic Society workshop report.
Ann Am Thorac Soc
17(4): 387-398, 2020. doi: 10.1513/AnnalsATS.202001-046ST
Sies H
, Jones DP:
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents.
Nat Rev Mol Cell Biol
21(7): 363-383, 2020. doi: 10.1038/s41580-020-0230-3
Abramson MJ,
Wigmann C
,
Altug H
,
Schikowski T
:
Ambient air pollution is associated with airway inflammation in older women: a nested cross-sectional analysis.
BMJ Open Respir Res
7: e000549, 2020. doi: 10.1136/bmjresp-2019-000549
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Dobner J
, Diecke S,
Krutmann J
, Prigione A,
Rossi A
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Reassessment of marker genes in human induced pluripotent stem cells for enhanced quality control
.
Nat Commun
15(1):8547, 2024. doi: 10.1038/s41467-024-52922-1
Lim HW, Passeron T, Goh CL, Kang HY, Ly F, Morita A, Ocampo-Candiani J, Puig S, Schalka S, Wei L, Demessant AL, Le Floc’h C, Kerob D, Dreno B,
Krutmann J
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Evaluating the frequency of mole checks by a dermatologist and correlated variables in a global survey across 17 Countries: HELIOS Project.
Acta Derm Venereol
104:adv40929, 2024. doi: 10.2340/actadv.v104.40929
Sant’Anna-Silva ACB, Botton T,
Rossi A
,
Dobner J
, Bzioueche H,
Thach N
, Blot L, Pagnotta S, Kleszczynski K, Steinbrink K, Mazure NM, Rocchi S,
Krutmann J
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Clin Transl Med
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Benzotriazole UV stabilizers disrupt epidermal growth factor receptor signaling in human cells.
Environ Int
190: 108886, 2024. doi: 10.1016/j.envint.2024.108886
Dreno B, Passeron T, Puig S, Lim HW, Goh CL, Kang HY, Ly F, Morita A, Ocampo-Candiani J, Schalka S, Wei L, Demessant AL, Le Floc’h C, Kerob D,
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The aryl hydrocarbon receptor in environmentally induced cancers
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Biochem Pharmacol
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Exploring the impact of solar radiation on skin microbiome to develop improved photoprotection strategies.
Photochem Photobiol
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Morita A, Lim HW, Passeron T, Goh CL, Kang HY, Ly F, Ocampo-Candiani J, Puig S, Schalka S, Wei L, Demessant AL, Le Floc’h C, Kerob D, Dreno B,
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Attitudes and behaviors regarding sun exposure in Japan compared to Europe and North America
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J Dermatol
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Outdoor workers and sun exposure: Results of an international survey on sun exposure behaviours and knowledge among 17 countries, the HELIOS project
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J Eur Acad Dermatol Venereol,
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Dobner J
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Photochem Photobiol Sci
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Stem Cell Res
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Evaluating the factors influencing sun protection factors (SPF): Pooling data from multiple studies involving two reference ISO 24444:2019 sunscreen products (P2 and P8)
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Photodermatol Photoimmunol Photomed
40:e12942, 2024. doi:10.1111/phpp.12942
Passeron T, Lim HW, Goh CL, Kang HY, Ribeyre C, Demessant-Flavigny AL, Le Floc’h C, Kerob D,
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Thirty years of promoting sun safety in France: The messages are heard but not followed!
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Nat Commun
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J Eur Acad Dermatol Venereol
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J Eur Acad Dermatol Venereol
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J Cosmet Dermatol
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Br J Dermatol
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Ecotoxicol Environ Saf
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Br J Dermatol
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Phenomics
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Matrix Biol
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Front Biosci (Landmark Ed)
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Front Genet
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Front Microbiol
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Development and characterisation of an irradiation device for biomedical studies covering the solar spectrum with individual regulated spectral bands
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Photochem Photobiol Sci
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Front Oncol
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Hautarzt
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Sonnenschutz der Zukunft: Herausforderungen und Möglichkeiten [Sunscreens of the future: challenges and opportunities]
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Front Oncol
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J Cosmet Dermatol
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Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs
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Skin Pharmacol Physiol
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Academic application of Good Cell Culture Practice for induced pluripotent stem cells
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ALTEX
38(4): 595-614, 2021. doi: 10.14573/altex.2101221
Baswan SM, Klosner AE, Weir C, Salter-Venzon D, Gellenbeck KW, Leveret J,
Krutmann J
:
Role of ingestible carotenoids in skin protection: A review of clinical evidence.
Photodermatol Photoimmunol Photomed
37(6): 490-504, 2021. doi: 10.1111/phpp.12690
Luger T, Amagai M, Dreno B, Dagnelie MA, Liao W, Kabashima K,
Schikowski T
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Atopic dermatitis: Role of the skin barrier, environment, microbiome, and therapeutic agents
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J Dermatol Sci
102(3): 142-157, 2021. doi: 10.1016/j.jdermsci.2021.04.007
Ramachandran H
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Rossi A
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Fast but not furious: a streamlined selection method for genome edited cells
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Life Sci Alliance
4(6): e202101051, 2021. doi: 10.26508/lsa.202101051
Krutmann J
, Schalka S, Watson REB, Liu W, Morita A:
Daily photoprotection to prevent photoaging.
Photodermatol Photoimmunol Photomed
37(6): 482-489
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2021. doi: 10.1111/phpp.12688
Correia Carreira S, Taghavi M,
Pavez Loriè E
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FleXert: A soft, actuatable multiwell plate insert for cell culture under stretch.
ACS Biomater Sci Eng
7(6): 2225-2245, 2021. doi: 10.1021/acsbiomaterials.0c01448
Zhao H, Wu J, Wang N,
Grether-Beck S
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Krutmann J
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Oral Pycnogenol® intake benefits the skin in urban Chinese outdoor workers: A randomized, placebo-controlled, double blind, and crossover intervention study.
Skin Pharmacol Physiol
34: 135-145, 2021. doi: 10.1159/000514323
Passeron T, Lim HW, Goh CL, Kang HY, Ly F, Morita A, Ocampo Candiani J, Puig S, Schalka S, Wei L, Dréno B,
Krutmann J
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Photoprotection according to skin phototype and dermatoses: Practical recommendations from an expert panel.
J Eur Acad Dermatol Venereol
35(7): 1460-1469, 2021. doi: 10.1111/jdv.17242
Vogel CFA, Lazennec G, Kado SY, Dahlem C, He Y, Castaneda A, Ishihara Y, Vogeley C,
Rossi A
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Haarmann-Stemmann T
, Jugan J, Mori H, Borowsky AD, La Merrill MA, Sweeney C:
Targeting the aryl hydrocarbon receptor signaling pathway in breast cancer development.
Front Immunol
12: 625346, 2021. doi: 10.3389/fimmu.2021.625346
Haarmann-Stemmann T
, Sutter TR,
Krutmann J
,
Esser C
:
The mode of action of tapinarof may not only depend on the activation of cutaneous aryl hydrocarbon receptor signaling but also on its antimicrobial activity.
J Am Acad Dermatol
85(1): e33-e34, 2021. doi: 10.1016/j.jaad.2021.01.103
Coppari S, Colomba M, Fraternale D,
Brinkmann V
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Romeo M
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Ventura N
, Albertini MC:
Antioxidant and anti-inflammaging ability of prune (Prunus Spinosa L.) extract result in improved wound healing efficacy
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Antioxidants (Basel)
10(3): 374, 2021. doi: 10.3390/antiox10030374
Li Z*, Xia J*, Jiang L, Tan Y, An Y, Zhu X, Ruan J, Chen Z, Zhen H, Ma Y, Jie Z, Xiao L, Yang H, Wang J, Kristiansen K, Xu X, Jin L, Nie C,
Krutmann J
*, Liu X*, Wang J*:
Characterization of the human skin resistome and identification of two microbiota cutotypes.
Microbiome
9(1): 47, 2021. doi: 10.1186/s40168-020-00995-7 (*equal contribution)
Esser C
:
Trajectory shifts in interdisciplinary research of the aryl hydrocarbon receptor – a personal perspective on thymus and skin.
Int J Mol Sci
22(4): 1844, 2021. doi: 10.3390/ijms22041844
Krutmann J
,
Schikowski T
, Morita A, Berneburg M:
Environmentally-induced (extrinsic) skin aging: Exposomal factors and underlying mechanisms.
J Invest Dermatol
141(4S): 1096-1103, 2021. doi: 10.1016/j.jid.2020.12.011
Sies H
:
Oxidative eustress: On constant alert for redox homeostasis.
Redox Biol
41: 101867, 2021. doi: 10.1016/j.redox.2021.101867
Neale RE, Barnes PW, Robson TM, Neale PJ, Williamson CE, Zepp RG, Wilson SR, Madronich S, Andrady AL, Heikkilä AM, Bernhard GH, Bais AF, Aucamp PJ, Banaszak AT, Bornman JF, Bruckman LS, Byrne SN, Foereid B, Häder DP, Hollestein LM, Hou WC, Hylander S, Jansen MAK, Klekociuk AR, Liley JB, Longstreth J, Lucas RM, Martinez-Abaigar J, McNeill K, Olsen CM, Pandey KK, Rhodes LE, Robinson SA, Rose KC,
Schikowski T
, Solomon KR, Sulzberger B, Ukpebor JE, Wang QW, Wängberg SÅ, White CC, Yazar S, Young AR, Young PJ, Zhu L, Zhu M:
Environmental effects of stratospheric ozone depletion, UV radiation, and interactions with climate change: UNEP Environmental Effects Assessment Panel, update 2020
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Photochem Photobiol Sci
20(1): 1-67, 2021. doi: 10.1007/s43630-020-00001-x
Krutmann J
, Berneburg M:
Photodermatologie.
Hautarzt
72(1): 1, 2021. doi: 10.1007/s00105-020-04746-5
Krutmann J
, Berneburg M:
Lichtalterung (Photoaging) der Haut: Was gibt es Neues?
Hautarzt
72(1): 2-5, 2021 (online 2020). doi: 10.1007/s00105-020-04747-4
Gappa M, Filipiak-Pittroff B, Libuda L, von Berg A, Koletzko S, Bauer CP, Heinrich J,
Schikowski T
, Berdel D, Standl M:
Long-term effects of hydrolyzed formulae on atopic diseases in the GINI study.
Allergy
76(6): 1903-1907, 2021 (online 2020). doi: 10.1111/all.14709
Mekić S,
Wigmann C
, Gunn DA, Kayser M, Jacobs LC,
Schikowski T
, Nijsten T, Pardo LM:
Genetics of facial telangiectasia in the Rotterdam study; a genome-wide association study and candidate gene approach
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J Eur Acad Dermatol Venereol
35(3): 749-754, 2021 (online 2020). doi: 10.1111/jdv.17014
Esser C
, Boots AM, Caignard A, Ciraci C, Grčević D, Knapp S, Montoya M, Di Rosa F, Saksida T, Stravinskiene D, Deniz G:
The impact of COVID-19 lock-downs for European (female) immunologists – our views as members of the EFIS gender and diversity task force.
Euro J Immunol
50(12): 1855-1862, 2020. doi: 10.1002/eji.202070125
Ghashghaei O, Pedrola M, Seghetti F, Martin VV, Zavarce R, Babiak M, Novacek J, Hartung F,
Rolfes KM
,
Haarmann-Stemmann T
, Lavilla R:
Extended multicomponent reactions with indole aldehydes: Access to unprecedented polyheterocyclic scaffolds, ligands of the aryl hydrocarbon receptor.
Angew Chem Int Edit
60(5): 2603-2608, 2021 (online 2020). doi: 10.1002/anie.202011253
Alkotob SS, Cannedy C, Harter K, Movassagh H, Paudel B, Prunicki M, Sampath V,
Schikowski T
, Smith E,
Zhao Q
, Traidl-Hoffmann C, Nadeau KC:
Advances and novel developments in environmental influences on the development of atopic diseases.
Allergy
75(12): 3077-3086, 2020. doi: 10.1111/all.14624
Sies H
:
Findings in redox biology: from H
2
O
2
to oxidative stress.
J Biol Chem
295(39): 13458-13473, 2020. doi: 10.1074/jbc.X120.015651
Pavez-Lorie E
, Stricker N, Plitta-Michalak B, Peng-Chen I, Volkmer B, Greinert R, Jauch A,
Boukamp P
, Rapp A:
Characterisation of the novel spontaneously immortalized and invasively growing human skin keratinocyte line HaSKpw.
Sci Rep
10(1): 15196, 2020. doi: 10.1038/s41598-020-71315-0
Sies H
:
Oxidative stress: Concept and some practical aspects.
Antioxidants
9(9): 852, 2020. doi: 10.3390/antiox9090852
Passeron T,
Krutmann J
, Andersen ML, Katta R, Zouboulis CC:
Clinical and biological impact of the exposome on the skin
.
J Eur Acad Dermatol Venereol
34 (Suppl 4): 4-25, 2020. doi: 10.1111/jdv.16614
Esser C
,
Hochrath K
,
Schikowski T
,
Haarmann-Stemmann T
:
COVID-19 research: toxicological input urgently needed!
Arch Toxicol
94(7): 2547-2548, 2020. doi: 10.1007/s00204-020-02803-5
Sies H
:
Schrödingers Koffer.
BIOspektrum
26: 345-346, 2020. doi: 10.1007/s12268-020-1364-8
Bernhard GH, Neale RE, Barnes PW, Neale PJ, Zepp RG, Wilson SR, Andrady AL, Bais AF, McKenzie RL, Aucamp PJ, Young PJ, Liley JB, Lucas RM, Yazar S, Rhodes LE, Byrne SN, Hollestein LM, Olsen CM, Young AR, Robson TM, Bornman JF, Jansen MAK, Robinson SA, Ballaré CL, Williamson CE, Rose KC, Banaszak AT, Häder DP, Hylander S, Wängberg SÅ, Austin AT, Hou WC, Paul ND, Madronich S, Sulzberger B, Solomon KR, Li H,
Schikowski T
, Longstreth J, Pandey KK, Heikkilä AM, White CC:
Environmental effects of stratospheric ozone depletion, UV radiation and interactions with climate change: UNEP Environmental Effects Assessment Panel, update 2019.
Photochem Photobiol Sci
19(5): 542-584, 2020. doi: 10.1039/d0pp90011g
Sies H
, Jones DP:
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents.
Nat Rev Mol Cell Biol
21(7): 363-383, 2020. doi: 10.1038/s41580-020-0230-3
Merches K
,
Schiavi A
, Weighardt H,
Steinwachs S
,
Teichweyde N
, Förster I,
Hochrath K
, Schumak B,
Ventura N
, Petzsch P, Köhrer K,
Esser C
:
AHR signaling dampens inflammatory signature in neonatal skin γδ T cells.
Int J Mol Sci
21(6): 2249, 2020. doi: 10.3390/ijms21062249
Häselbarth L
, Ouwens DM,
Teichweyde N
,
Hochrath K
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Merches K
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Esser C
:
The small chain fatty acid butyrate antagonizes the TCR-stimulation-induced metabolic shift in murine epidermal gamma delta T cells
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EXCLI J
19: 334-350, 2020. doi: 10.17179/excli2020-1123
Madhusudhan N, Pausan MR, Halwachs B, Durdević M, Windisch M, Kehrmann J, Patra V, Wolf P,
Boukamp P
, Moissl-Eichinger C, Cerroni L, Becker JC, Gorkiewicz G:
Molecular profiling of keratinocyte skin tumors links Staphylococcus aureus overabundance and increased human
β
-Defensin-2 expression to growth promotion of squamous cell carcinoma.
Cancers
(Basel) 12(3): 541, 2020. doi: 10.3390/cancers12030541
Pavez Loriè E
,
Boukamp P
:
Methods in cell biology: Cell-derived matrices
.
Methods Cell Biol
156: 309-332, 2020. doi: 10.1016/bs.mcb.2019.11.012
Baswan SM,
Marini A
, Klosner AE,
Jaenicke T
, Leverett J, Murray M, Gellenbeck KW,
Krutmann J
:
Orally administered mixed carotenoids protect human skin against ultraviolet A-induced skin pigmentation: A double-blind, placebo-controlled, randomized clinical trial.
Photodermatol Photoimmunol Photomed
36(3): 219-225, 2020. doi: 10.1111/phpp.12541
Tan Y, Wang F, Fan G, Yan Z, Li B, Li N, Liu Y, Wang X, Liu W,
Krutmann J
, Zou Y, Wang S:
Identification of factors associated with minimal erythema dose variations in a large-scale population study of 22 146 subjects.
J Eur Acad Dermatol Venereol
34(7): 1595-1600, 2020. doi: 10.1111/jdv.16206
Schikowski T
, Hüls A:
Air pollution and skin aging
.
Curr Environ Health Rep
7(1): 58-64, 2020. doi: 10.1007/s40572-020-00262-9
Lademann J, Richter H, Patzelt A, Meinke MC, Gross I,
Grether-Beck S
,
Krutmann J
, Frazier L, Darvin ME:
Laser scanning microscopy for control of skin decontamination efficacy from airborne particulates using highly absorbent textile nanofiber material in combination with PEG-12 dimethicone.
Skin Res Technol
26(4): 558-563, 2020. doi: 10.1111/srt.12830
Krutmann J
, Passeron T, Gilaberte Y, Granger C, Leone G, Narda M, Schalka S, Trullas C, Masson P, Lim HW:
Photoprotection of the future: Challenges and opportunities.
J Eur Acad Dermatol Venereol
34(3): 447-454, 2020. doi: 10.1111/jdv.16030
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Dobner J
, Diecke S,
Krutmann J
, Prigione A,
Rossi A
:
Reassessment of marker genes in human induced pluripotent stem cells for enhanced quality control
.
Nat Commun
15(1):8547, 2024. doi: 10.1038/s41467-024-52922-1
Kapr J
,
Scharkin I
,
Ramachandran H
, Westhoff P,
Pollet M
,
Dangeleit S
,
Brockerhoff G
,
Rossi A
,
Koch K
,
Krutmann J
,
Fritsche E
:
HiPSC-derived 3D neural models reveal neurodevelopmental pathomechanisms of the Cockayne Syndrome B
.
Cell Mol Life Sci
81(1):368, 2024. doi: 10.1007/s00018-024-05406-w
Piragine E, De Felice M, Germelli L, Brinkmann V, Flori L, Martini C, Calderone V,
Ventura N
, Da Pozzo E, Testai L:
The Citrus flavanone naringenin prolongs the lifespan in C. elegans and slows signs of brain aging in mice
.
Exp Gerontol
194:112495, 2024. doi: 10.1016/j.exger.2024.112495
Dugershaw-Kurzer B, Bossart J, Buljan M, Hannig Y, Zehnder S, Gupta G, Kissling VM, Nowak-Sliwinska P, van Beijnum JR, Griffioen AW,
Masjosthusmann S
,
Zühr E
,
Fritsche E
, Hornung R, Rduch T, Buerki-Thurnherr T:
Nanoparticles dysregulate the human placental secretome with consequences on angiogenesis and vascularization
.
Adv Sci (Weinh)
20: e2401060, 2024. doi: 10.1002/advs.202401060
Fehsel K, Bouvier M-L, Capobianco L, Lunetti P, Klein B, Oldiges M,
Majora M
, Löffler S:
Neuroreceptor inhibition by Clozapine triggers mitohormesis and metabolic reprogramming in human blood cells
.
Cells
13(9): 762, 2024. doi: 10.3390/cells13090762
Tal T, Myhre O,
Fritsche E
, Rüegg J, Craenen K, Aiello-Holden K, Agrillo C, Babin PJ, Escher BI, Dirven H, Hellsten K, Dolva K, Hessel E, Heusinkveld HJ, Hadzhiev Y, Hurem S, Jagiello K, Judzinska B, Klüver N, Knoll-Gellida A, Kühne BA, Leist M, Lislien M, Lyche JL, Müller F, Colbourne JK, Neuhaus W, Pallocca G, Seeger B,
Scharkin I
, Scholz S, Spjuth O, Torres-Ruiz M,
Bartmann K
:
New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project
.
Front Toxicol
6: 1359507, 2024. doi: 10.3389/ftox.2024.1359507
Holz A, Obi N, Ahrens W, Berger K, Bohn B, Brenner H, Fischer B, Fricke J, Führer A, Gastell S, Greiser KH, Harth V, Heise JK, Holleczek B, Keil T, Klett-Tammen CJ, Leitzmann M, Lieb W, Meinke-Franze C, Michels KB, Mikolajczyk R, Nimptsch K, Peters A, Pischon T, Riedel O,
Schikowski T
, Schipf S, Schmidt B, Schulze MB, Stang A, Hellwig K, Riemann-Lorenz K, Heesen C, Becher H:
Childhood and adolescence factors and multiple sclerosis: results from the German National Cohort (NAKO)
.
BMC Neurol
24(1): 123, 2024. doi: 10.1186/s12883-024-03620-4
Szepanowski LP
, Wruck W,
Kapr J
,
Rossi A
,
Fritsche E
,
Krutmann J
, Adjaye J:
Cockayne syndrome patient iPSC-derived brain organoids and neurospheres show early transcriptional dysregulation of biological processes associated with brain development and metabolism
.
Cells
13(7): 591, 2024. doi: 10.3390/cells13070591
Dobner J
,
Nguyen T
, Pavez-Giani MG, Cyganek L, Distelmaier F,
Krutmann J
, Prigione A,
Rossi A
:
mtDNA Analysis using Mitopore.
Mol Ther Methods Clin Dev
32(2): 101231, 2024. doi: 10.1016/j.omtm.2024.101231
Jaylet T, Coustillet T, Smith NM, Viviani B, Lindeman B, Vergauwen L, Myhre O, Yarar N, Gostner JM, Monfort-Lanzas P, Jornod F, Holbech H, Coumoul X, Sarigiannis DA, Antczak P, Bal-Price A,
Fritsche E
,
Kuchovska E
, Stratidakis AK, Barouki R, Kim MJ, Taboureau O, Wojewodzic MW, Knapen D, Audouze K:
Comprehensive mapping of the AOP-Wiki database: identifying biological and disease gaps
.
Front Toxicol
6: 1285768, 2024. doi: 10.3389/ftox.2024.1285768
Dobner J
,
Nguyen T
, Dunkel A, Prigione A,
Krutmann J
,
Rossi A
:
Mitochondrial DNA integrity and metabolome profile are preserved in the human induced pluripotent stem cell reference line KOLF2.1J
.
Stem Cell Rep
19(3): 343-350, 2024. doi: 10.1016/j.stemcr.2024.01.009
Cibelli A, Mola MG, Saracino E, Barile B, Abbrescia P, Mogni G, Spray DC, Scemes E,
Rossi A
, Spennato D, Svelto M, Frigeri A, Benfenati V, Nicchia GP:
Aquaporin-4 and transient receptor potential vanilloid 4 balance in early postnatal neurodevelopment
.
Glia
72(5): 938-959, 2024. doi: 10.1002/glia.24512
Diemar MG, Vinken M, Teunis M, Krul CAM, Busquet F, Zajac JD, Kandarova H, Corvi R, Rosso MZ, Kharina A, Bryndum LS, Santillo M, Bloch D, Kucheryavenko O, Panagiotakos D, Rogiers V, Beekhuijzen M, Giusti A, Najjar A, Courage C, Koenig T, Kolle S, Boonen H, Dhalluin S, Boberg J, Müller BP, Kukic P, Ritskes-Hoitinga M, Grasselli E, Zietek T, Stoddart G, Heusinkveld HJ, Castell JV, Benfenati E, Yang H, Perera S, Paini A, Kramer NI, Hartung T, Janssen M, Fritsche E, Jennen DGJ, Piumatti M, Rathman J, Marusczyk J, Milec L, Roggen EL: Report of the first ONTOX stakeholder network meeting: Digging under the surface of ONTOX together with the stakeholders. Altern Lab Anim 52(2): 117-131, 2024. doi: 10.1177/02611929231225730
Liu BP, Huxley RR,
Schikowski T
, Hu KJ, Zhao Q, Jia CX:
Exposure to residential green and blue space and the natural environment is associated with a lower incidence of psychiatric disorders in middle-aged and older adults: findings from the UK Biobank
.
BMC Med
22: 15, 2024. https://doi.org/10.1186/s12916-023-03239-1
Limke A
, Poschmann G, Stühler K, Petzsch P, Wachtmeister T,
von Mikecz A
:
Silica nanoparticles disclose a detailed neurodegeneration profile throughout the life span of a model organism
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J Xenobiotics
14(1): 135-153, 2024. doi: 10.3390/jox14010008
Binder S
,
Ramachandran H
, Hildebrandt B,
Dobner J
,
Rossi A:
Prime-Editing of human ACTB in induced pluripotent stem cells to model human ACTB Loss-of-Function diseases and compensatory mechanisms
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Stem Cell Res
75:103304, 2024. doi: 10.1016/j.scr.2024.103304
Bloch S, Lévêque L, Hertz-Picciotto I, Puschner B,
Fritsche E
,
Klose J
, I Kramer N, Bouchard MF, Chandrasekera PC, Verner MA:
Using in vitro data to derive acceptable exposure levels: A case study on PBDE developmental neurotoxicity.
Environ Int 183: 108411, 2024 (online 2023). doi: 10.1016/j.envint.2023.108411
Schröter L
,
Jentsch L
,
Maglioni S
, Muñoz-Juan A,
Wahle T
,
Limke A
,
von Mikecz A
, Laromaine A,
Ventura N
:
A multisystemic approach revealed aminated polystyrene nanoparticles-induced neurotoxicity
.
Small
e2302907, 2024. doi: 10.1002/smll.202302907
von Mikecz A
:
Elegant nematodes improve our understanding of human neuronal diseases, the role of pollutants and strategies of resilience
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Environ Sci Technol
57(44)
:16755-16763
, 2023. doi: 10.1021/acs.est.3c04580
Tanabe S, Beaton D, Chauhan V, Choi I, Choi J, Clerbaux LA, Coppola L, Dumont AF, Esterhuizen M, Filipovska J, FitzGerald R,
Fritsche E
, Garcia-Reyero N, Goralczyk A, Huliganga E, Kim YJ,
Klose J
, La Rocca C, Landesmann B, Mally A, Murugadoss S, Omeragic E, Ouédraogo G, Pereira JM, Sadi B, Schaffert A, Song Y, Sovadinova I, Stöger T, Tollefsen KE, Wittwehr C, Yauk C:
Report of the 3rd and 4th mystery of reactive oxygen species conference
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ALTEX
40(4):689-693, 2023. doi: 10.14573/altex.2307041
Schiavi A
, Cirotti C,
Gerber LS
,
Di Lauro G
, Petzsch P, Köhrer KE,
Schins RPF
,
Wahle T
, Barilà D,
Ventura N:
Abl depletion via autophagy mediates the beneficial effects of quercetin against Alzheimer pathology across species.
Cell Death Discov
9 (1): 376, 2023. doi: 10.1038/s41420-023-01592-x
Romero NG, Gutierrez G, Teixidó E, Li L,
Klose J
, Leung PC, Cañigueral S,
Fritsche E
, Barenys M:
Developmental neurotoxicity evaluation of three Chinese herbal medicines in zebrafish larvae by means of two behavioral assays: Touch-evoked response and light/dark transition
.
Reprod Toxicol
121: 108469, 2023. doi: 10.1016/j.reprotox.2023.108469
Schumann G, Andreassen OA, Banaschewski T, Calhoun VD, Clinton N, Desrivieres S, Brandlistuen RE, Feng J, Hese S, Hitchen E, Hoffmann P, Jia T, Jirsa V, Marquand AF, Nees F, Nöthen MM, Novarino G, Polemiti E, Ralser M, Rapp M, Schepanski K,
Schikowski T
, Slater M, Sommer P, Stahl BC, Thompson PM, Twardziok S, van der Meer D, Walter H, Westlye L; environMENTAL Consortium:
Addressing global environmental challenges to mental health using population neuroscience: A review.
JAMA Psychiatry
80(10): 1066-1074, 2023. doi: 10.1001/jamapsychiatry.2023.2996
De Castelbajac T, Aiello K, Arenas CG, Svingen T, Ramhøj L, Zalko D, Barouki R, Vanhaecke T, Rogiers V, Audebert M, Oelgeschlaeger M, Braeuning A, Blanc E, Tal T, Rüegg J,
Fritsche E
, Marx-Stoelting P, Rivière G:
Innovative tools and methods for toxicity testing within PARC work package 5 on hazard assessment
.
Front Toxicol
5:1216369, 2023. doi: 10.3389/ftox.2023.1216369
Vonneilich N, Becher H, Bohn B, Brandes B, Castell S, Deckert A, Dragano N, Franzke C-W, Führer A, Gastell S, Greiser H, Keil T, Klett-Tammen C, Koch-Gallenkamp L, Krist L, Leitzmann M, Meinke-Franze C, Mikolajczyk R, Moreno Velasquez I, Obi N, Peters A, Pischon T, Reuter M,
Schikowski T
, Schmidt B, Schulze M, Sergeev D, Stang A, Völzke H, Wiessner C, Zeeb H, Lüdecke D, von dem Knesebeck O:
Associations of migration, socioeconomic position and social relations with depressive symptoms – Analyses of the German national cohort baseline data
.
Int J Public Health
68: 1606097, 2023. doi: 10.3389/ijph.2023.1606097
Kessel HE
,
Masjosthusmann S
,
Bartmann K
, Blum J,
Dönmez A
, Förster N,
Klose J
, Mosig A,
Pahl M
, Leist M, Scholze M,
Fritsche E
:
The impact of biostatistics on hazard characterization using in vitro developmental neurotoxicity assays
.
ALTEX
40(4): 619–634, 2023. doi: 10.14573/altex.2210171
Bartmann K
,
Bendt F
,
Dönmez A
, Haag D,
Keßel HE
,
Masjosthusmann S
, Noel C, Wu J, Zhou P,
Fritsche E
:
A human iPSC-based in vitro neural network formation assay to investigate neurodevelopmental toxicity of pesticides
.
ALTEX
40(3): 452–470, 2023. doi: 10.14573/altex.2206031
Hartmann J
,
Henschel N
,
Bartmann K
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Different calculation strategies are congruent in determining chemotherapy resistance of brain tumors in vitro.
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Pharmaceuticals
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Editorial: Air pollution and brain health.
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Interaction between magnesium and methylglyoxal in diabetic polyneuropathy and neuronal models.
Mol Metab
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Esser C
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The impact of COVID-19 lock-downs for European (female) immunologists – our views as members of the EFIS gender and diversity task force.
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ALTEX
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Editorial: Advances in metabolic mechanisms of aging and its related diseases.
Front Physiol
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Rabbit neurospheres as a novel in vitro tool for studying neurodevelopmental effects induced by intrauterine growth restriction.
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Oxidative stress: Concept and some practical aspects.
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Effects of airborne nanoparticles on the nervous system: amyloid protein aggregation, neurodegeneration and neurodegenerative diseases
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Nanomaterials
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Impact of residential green space on sleep quality and sufficiency in children and adolescents residing in Australia and Germany.
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Frontiers in Toxicol
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The ENDpoiNTs project: Novel testing strategies for endocrine disruptors linked to developmental neurotoxicity.
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Mech Ageing Dev
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Reactive oxygen species (ROS) as pleiotropic physiological signalling agents.
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Association between objectively assessed physical activity and sleep quality in adolescence. Results from the GINIplus and LISA studies.
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Air pollution is associated with depressive symptoms in elderly women with cognitive impairment.
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Dobner J
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Krutmann J
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Rossi A
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Reassessment of marker genes in human induced pluripotent stem cells for enhanced quality control
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Nat Commun
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Mayer M, Cengiz-Dartenne SC, Thiem M, Hatzfeld P, Semeniuk A, Wang N, Strugnell RA, Förster I,
Weighardt H
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Dysregulation of stress erythropoiesis and enhanced susceptibility to Salmonella Typhimurium infection in AhR-deficient mice
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J Infect Dis
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Esser C
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Differential cell type-specific function of the aryl hydrocarbon receptor and its repressor in diet-induced obesity and fibrosis.
Mol Metab
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Dobner J
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mtDNA Analysis using Mitopore.
Mol Ther Methods Clin Dev
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Mitochondrial DNA integrity and metabolome profile are preserved in the human induced pluripotent stem cell reference line KOLF2.1J
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Stem Cell Rep
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Binder S
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Prime-Editing of human ACTB in induced pluripotent stem cells to model human ACTB Loss-of-Function diseases and compensatory mechanisms
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Stem Cell Res
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Lkhagva-Yondon E, Seo MS, Oh Y, Jung J, Jeon E, Na K, Yoo HS, Kim WC,
Esser C
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The aryl hydrocarbon receptor controls mesenchymal stromal cell-mediated immunomodulation via ubiquitination of eukaryotic elongation factor-2 kinase
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Cell Death Dis
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European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.
Nat Commun
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Libuda L, Filipiak-Pittroff B, Standl M,
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Full breastfeeding and allergic diseases-long-term protection or rebound effects?
Nutrients
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Kado SY, Bein K, Castaneda AR, Pouraryan AA, Garrity N, Ishihara Y,
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Regulation of IDO2 by the aryl hydrocarbon receptor (AhR) in breast cancer
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Cells
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Thiering E, Markevych I,
Kress S
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Altug H
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Gene-environment interaction in the association of residential greenness and 25(OH) vitamin D
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Environ Pollut
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The Ah receptor from toxicity to therapeutics: Report from the 5th AHR meeting at Penn State University, USA, June 2022
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Int J Mol Sci
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Clahsen T, Hadrian K, Notara M, Schlereth SL, Howaldt A, Prokosch V, Volatier T, Hos D, Schroedl F, Kaser-Eichberger A, Heindl LM, Steven P, Bosch JJ, Steinkasserer A, Rokohl AC, Liu H, Mestanoglu M, Kashkar H, Schumacher B, Kiefer F, Schulte-Merker S, Matthaei M, Hou Y,
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Biochem Pharmacol
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Schikowski T
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Dietary digestible carbohydrates are associated with higher prevalence of asthma in humans and with aggravated lung allergic inflammation in mice
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Allergy
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Allergy
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Birth order, caesarean section, or daycare attendance in relation to child- and adult-onset type 1 diabetes: Results from the German National Cohort
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Int J Environ Res Public Health
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Exposome, molecular pathways and one health: The invertebrate
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Front Biosci (Landmark Ed)
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Rapid and simple analysis of short and long sequencing reads using Duesselpore
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Front Genet
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Assessing the NLRP3 inflammasome activating potential of a large panel of micro- and nanoplastics in THP-1 cells.
Biomolecules
12(8): 1095, 2022. doi: 10.3390/biom12081095
Busch M
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Ramachandran H
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Investigating the role of the NLRP3 inflammasome pathway in acute intestinal inflammation: use of THP-1 knockout cell lines in an advanced triple culture model
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Interlaboratory comparison of an intestinal triple culture to confirm transferability and reproducibility.
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Identification of genome edited cells using CRISPRnano
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Schins RPF
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The road to achieving the European Commission’s chemicals strategy for nanomaterial sustainability-A PATROLS perspective on new approach methodologies
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Small
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A call for consensus guidelines on monitoring the integrity of nuclear and mitochondrial genomes in human pluripotent stem cells
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Stem Cell Rep
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Sies H
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Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
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Fueldner C, Riemschneider S, Haupt J, Jungnickel H, Schulze F, Zoldan K,
Esser C
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Aryl Hydrocarbon Receptor activation by benzo[a]pyrene prevents development of septic shock and fatal outcome in a mouse model of systemic Salmonella enterica infection
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Cells
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Ingested engineered nanomaterials affect the expression of mucin genes—an in vitro – in vivo comparison
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Nanomaterials
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Faßbender S
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Haarmann-Stemmann T
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Keratinocytes counteract UVB-induced immunosuppression in mice via HIF1a signaling
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J Invest Dermatol
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Effects of dietary exposure to the engineered nanomaterials CeO
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Nanotoxicology
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